EC: 3.1.1.4

phospholipase A2 (phosphatidylcholine 2-acylhydrolase)

enzyme lambda metabolic reaction experiment
uniprot:P47713 [phospholipase A2(Enzyme) wildtype EGF-stimulated]

1_Stearoyl_2_arachidonoyl_sn_glycero_3_phosphocholine + H2O -> Arachidonate + Stearoyllysophosphatidylcholine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.2 M Tris, 1 mM CaCl2
PH: 9
Temperature: 37
uniprot:Q7T3S7 [phospholipase A2(Enzyme) wildtype]

Phosphatidylcholine + H2O -> 1_Acyl_sn_glycero_3_phosphocholine + Carboxylate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 0.3 ml diethyl ether, 40 mM Ca2+
PH: 7.5
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA2CBc]

H2O + 1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA2CBb]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA2CBa2]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA3CBa2]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 10_Pyren_1_yldecanoic_acid + 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA3CBb]

H2O + 1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid -> 10_Pyren_1_yldecanoic_acid + 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
uniprot:P0CG56 [phospholipase A2(Enzyme) wildtype CBb]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
uniprot:P62022 [phospholipase A2(Enzyme) wildtype CBc]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
uniprot:P24027 [phospholipase A2(Enzyme) wildtype CBa2]

H2O + 1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid -> 10_Pyren_1_yldecanoic_acid + 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.5
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA3CBc]

H2O + 1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA2CBd]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CA3CBd]

H2O + 1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36
- [phospholipase A2(Enzyme) wildtype CBd]

1_Palmitoyl_2_(10_pyrenyldecanoyl)_sn_glycero_3_monomethyl_phosphatidic_acid + H2O -> 1_Palmitoylglycero_3_monomethyl_phosphatidic_acid + 10_Pyren_1_yldecanoic_acid		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, 6 mM CaCl2, 0.1% serum albumin
PH: 7.4
Temperature: 36

Pathways

pathway id name
BioCyc:HUMAN_LIPAS-PWY triacylglycerol degradation
BioCyc:MOUSE_PWY-6355 phosphate acquisition II
BioCyc:ARA_PWY-6803 phosphatidylcholine acyl editing
BioCyc:ARA_LIPASYN-PWY phospholipases
BioCyc:ECOO157_LIPASYN-PWY phospholipases
BioCyc:MOUSE_LIPAS-PWY triacylglycerol degradation
BioCyc:HUMAN_LIPASYN-PWY phospholipases
BioCyc:META_LIPASYN-PWY phospholipases
BioCyc:MOUSE_LIPASYN-PWY phospholipases
PlantCyc:ARA_LIPASYN-PWY phospholipases
PlantCyc:ARA_PWY-6803 phosphatidylcholine acyl editing
PlantCyc:PLANT_LIPASYN-PWY phospholipases
Reactome:R-RNO-9711123 Cellular response to chemical stress
Reactome:R-HSA-9709957 Sensory Perception
Reactome:R-SSC-9711123 Cellular response to chemical stress
Reactome:R-BTA-9711123 Cellular response to chemical stress
Reactome:R-MMU-9711123 Cellular response to chemical stress
Reactome:R-MMU-9709957 Sensory Perception
Reactome:R-RNO-9709957 Sensory Perception
Reactome:R-HSA-9711123 Cellular response to chemical stress
Reactome:R-HSA-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-HSA-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-HSA-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-HSA-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-BTA-109582 Hemostasis
Reactome:R-BTA-432142 Platelet sensitization by LDL
Reactome:R-BTA-392518 Signal amplification
Reactome:R-BTA-168256 Immune System
Reactome:R-BTA-6803157 Antimicrobial peptides
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-556833 Metabolism of lipids
Reactome:R-BTA-1482801 Acyl chain remodelling of PS
Reactome:R-BTA-1482925 Acyl chain remodelling of PG
Reactome:R-BTA-8953897 Cellular responses to stimuli
Reactome:R-BTA-2262752 Cellular responses to stress
Reactome:R-BTA-418594 G alpha (i) signalling events
Reactome:R-BTA-112043 PLC beta mediated events
Reactome:R-CFA-1430728 Metabolism
Reactome:R-CFA-556833 Metabolism of lipids
Reactome:R-CFA-1482801 Acyl chain remodelling of PS
Reactome:R-CFA-1482925 Acyl chain remodelling of PG
Reactome:R-DRE-372790 Signaling by GPCR
Reactome:R-DRE-112040 G-protein mediated events
Reactome:R-DRE-8978868 Fatty acid metabolism
Reactome:R-DRE-1483166 Synthesis of PA
Reactome:R-DRE-1482798 Acyl chain remodeling of CL
Reactome:R-GGA-8978868 Fatty acid metabolism
Reactome:R-GGA-372790 Signaling by GPCR
Reactome:R-GGA-111885 Opioid Signalling
Reactome:R-GGA-111996 Ca-dependent events
Reactome:R-HSA-163560 Triglyceride catabolism
Reactome:R-HSA-1483191 Synthesis of PC
Reactome:R-HSA-112040 G-protein mediated events
Reactome:R-HSA-381070 IRE1alpha activates chaperones
Reactome:R-HSA-74160 Gene expression (Transcription)
Reactome:R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
Reactome:R-MMU-168256 Immune System
Reactome:R-MMU-168249 Innate Immune System
Reactome:R-MMU-6803157 Antimicrobial peptides
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-1483191 Synthesis of PC
Reactome:R-MMU-76002 Platelet activation, signaling and aggregation
Reactome:R-MMU-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-MMU-3299685 Detoxification of Reactive Oxygen Species
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-MMU-388396 GPCR downstream signalling
Reactome:R-MMU-111885 Opioid Signalling
Reactome:R-MMU-111996 Ca-dependent events
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-1483166 Synthesis of PA
Reactome:R-RNO-1483115 Hydrolysis of LPC
Reactome:R-RNO-1482922 Acyl chain remodelling of PI
Reactome:R-RNO-1482798 Acyl chain remodeling of CL
Reactome:R-RNO-162582 Signaling Pathways
Reactome:R-RNO-372790 Signaling by GPCR
Reactome:R-RNO-111995 phospho-PLA2 pathway
Reactome:R-RNO-109582 Hemostasis
Reactome:R-RNO-432142 Platelet sensitization by LDL
Reactome:R-RNO-392518 Signal amplification
Reactome:R-RNO-2029485 Role of phospholipids in phagocytosis
Reactome:R-SSC-8953897 Cellular responses to stimuli
Reactome:R-SSC-2262752 Cellular responses to stress
Reactome:R-XTR-76002 Platelet activation, signaling and aggregation
Reactome:R-XTR-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-XTR-8978868 Fatty acid metabolism
Reactome:R-XTR-1482925 Acyl chain remodelling of PG
Reactome:R-XTR-418594 G alpha (i) signalling events
Reactome:R-XTR-112043 PLC beta mediated events
Reactome:R-BTA-168249 Innate Immune System
Reactome:R-BTA-8978868 Fatty acid metabolism
Reactome:R-BTA-1483166 Synthesis of PA
Reactome:R-BTA-1483191 Synthesis of PC
Reactome:R-BTA-162582 Signaling Pathways
Reactome:R-BTA-372790 Signaling by GPCR
Reactome:R-BTA-112040 G-protein mediated events
Reactome:R-CFA-1483166 Synthesis of PA
Reactome:R-DRE-162582 Signaling Pathways
Reactome:R-DRE-111995 phospho-PLA2 pathway
Reactome:R-DRE-2142753 Arachidonate metabolism
Reactome:R-DRE-1483206 Glycerophospholipid biosynthesis
Reactome:R-DRE-1482839 Acyl chain remodelling of PE
Reactome:R-DRE-1482788 Acyl chain remodelling of PC
Reactome:R-DRE-76002 Platelet activation, signaling and aggregation
Reactome:R-DRE-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-GGA-2142753 Arachidonate metabolism
Reactome:R-GGA-418594 G alpha (i) signalling events
Reactome:R-GGA-112043 PLC beta mediated events
Reactome:R-GGA-76002 Platelet activation, signaling and aggregation
Reactome:R-GGA-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-HSA-76002 Platelet activation, signaling and aggregation
Reactome:R-HSA-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-1483166 Synthesis of PA
Reactome:R-HSA-1483152 Hydrolysis of LPE
Reactome:R-HSA-1483115 Hydrolysis of LPC
Reactome:R-HSA-1482922 Acyl chain remodelling of PI
Reactome:R-HSA-1482798 Acyl chain remodeling of CL
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-975634 Retinoid metabolism and transport
Reactome:R-HSA-372790 Signaling by GPCR
Reactome:R-HSA-111995 phospho-PLA2 pathway
Reactome:R-HSA-2262752 Cellular responses to stress
Reactome:R-HSA-212165 Epigenetic regulation of gene expression
Reactome:R-HSA-2029485 Role of phospholipids in phagocytosis
Reactome:R-MMU-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-1483166 Synthesis of PA
Reactome:R-MMU-1483152 Hydrolysis of LPE
Reactome:R-MMU-1483115 Hydrolysis of LPC
Reactome:R-MMU-1482922 Acyl chain remodelling of PI
Reactome:R-MMU-1482798 Acyl chain remodeling of CL
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-MMU-975634 Retinoid metabolism and transport
Reactome:R-MMU-418346 Platelet homeostasis
Reactome:R-MMU-418594 G alpha (i) signalling events
Reactome:R-MMU-112043 PLC beta mediated events
Reactome:R-MMU-2187338 Visual phototransduction
Reactome:R-RNO-2142753 Arachidonate metabolism
Reactome:R-RNO-1483206 Glycerophospholipid biosynthesis
Reactome:R-RNO-1482839 Acyl chain remodelling of PE
Reactome:R-RNO-1482788 Acyl chain remodelling of PC
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-975634 Retinoid metabolism and transport
Reactome:R-RNO-8953897 Cellular responses to stimuli
Reactome:R-RNO-2262752 Cellular responses to stress
Reactome:R-RNO-388396 GPCR downstream signalling
Reactome:R-RNO-111885 Opioid Signalling
Reactome:R-RNO-111996 Ca-dependent events
Reactome:R-RNO-168256 Immune System
Reactome:R-RNO-168249 Innate Immune System
Reactome:R-XTR-418346 Platelet homeostasis
Reactome:R-XTR-2142753 Arachidonate metabolism
Reactome:R-XTR-1483166 Synthesis of PA
Reactome:R-XTR-112040 G-protein mediated events
Reactome:R-BTA-418346 Platelet homeostasis
Reactome:R-BTA-1483257 Phospholipid metabolism
Reactome:R-BTA-1482788 Acyl chain remodelling of PC
Reactome:R-BTA-388396 GPCR downstream signalling
Reactome:R-BTA-111885 Opioid Signalling
Reactome:R-BTA-111996 Ca-dependent events
Reactome:R-CFA-1483257 Phospholipid metabolism
Reactome:R-CFA-1482788 Acyl chain remodelling of PC
Reactome:R-DRE-418594 G alpha (i) signalling events
Reactome:R-DRE-112043 PLC beta mediated events
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DRE-556833 Metabolism of lipids
Reactome:R-DRE-109582 Hemostasis
Reactome:R-DRE-432142 Platelet sensitization by LDL
Reactome:R-DRE-392518 Signal amplification
Reactome:R-GGA-1430728 Metabolism
Reactome:R-GGA-556833 Metabolism of lipids
Reactome:R-GGA-1483257 Phospholipid metabolism
Reactome:R-GGA-388396 GPCR downstream signalling
Reactome:R-GGA-111995 phospho-PLA2 pathway
Reactome:R-GGA-109582 Hemostasis
Reactome:R-GGA-432142 Platelet sensitization by LDL
Reactome:R-GGA-392518 Signal amplification
Reactome:R-HSA-109582 Hemostasis
Reactome:R-HSA-432142 Platelet sensitization by LDL
Reactome:R-HSA-392518 Signal amplification
Reactome:R-HSA-1483257 Phospholipid metabolism
Reactome:R-HSA-1482801 Acyl chain remodelling of PS
Reactome:R-HSA-1482925 Acyl chain remodelling of PG
Reactome:R-HSA-6806667 Metabolism of fat-soluble vitamins
Reactome:R-HSA-418594 G alpha (i) signalling events
Reactome:R-HSA-112043 PLC beta mediated events
Reactome:R-HSA-2187338 Visual phototransduction
Reactome:R-HSA-3299685 Detoxification of Reactive Oxygen Species
Reactome:R-HSA-381119 Unfolded Protein Response (UPR)
Reactome:R-HSA-381038 XBP1(S) activates chaperone genes
Reactome:R-HSA-168256 Immune System
Reactome:R-HSA-168249 Innate Immune System
Reactome:R-MMU-1483257 Phospholipid metabolism
Reactome:R-MMU-1482801 Acyl chain remodelling of PS
Reactome:R-MMU-1482925 Acyl chain remodelling of PG
Reactome:R-MMU-6806667 Metabolism of fat-soluble vitamins
Reactome:R-MMU-372790 Signaling by GPCR
Reactome:R-MMU-111995 phospho-PLA2 pathway
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-6806667 Metabolism of fat-soluble vitamins
Reactome:R-RNO-3299685 Detoxification of Reactive Oxygen Species
Reactome:R-RNO-112040 G-protein mediated events
Reactome:R-RNO-2187338 Visual phototransduction
Reactome:R-RNO-418346 Platelet homeostasis
Reactome:R-RNO-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
Reactome:R-XTR-1430728 Metabolism
Reactome:R-XTR-556833 Metabolism of lipids
Reactome:R-XTR-1483257 Phospholipid metabolism
Reactome:R-XTR-388396 GPCR downstream signalling
Reactome:R-XTR-111885 Opioid Signalling
Reactome:R-XTR-111996 Ca-dependent events
Reactome:R-BTA-76002 Platelet activation, signaling and aggregation
Reactome:R-BTA-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-BTA-2142753 Arachidonate metabolism
Reactome:R-BTA-1483206 Glycerophospholipid biosynthesis
Reactome:R-BTA-1482839 Acyl chain remodelling of PE
Reactome:R-BTA-1483115 Hydrolysis of LPC
Reactome:R-BTA-1482922 Acyl chain remodelling of PI
Reactome:R-BTA-1482798 Acyl chain remodeling of CL
Reactome:R-BTA-3299685 Detoxification of Reactive Oxygen Species
Reactome:R-BTA-111995 phospho-PLA2 pathway
Reactome:R-CFA-1483206 Glycerophospholipid biosynthesis
Reactome:R-CFA-1482839 Acyl chain remodelling of PE
Reactome:R-CFA-1482922 Acyl chain remodelling of PI
Reactome:R-DRE-388396 GPCR downstream signalling
Reactome:R-DRE-111885 Opioid Signalling
Reactome:R-DRE-111996 Ca-dependent events
Reactome:R-DRE-1483257 Phospholipid metabolism
Reactome:R-DRE-1482801 Acyl chain remodelling of PS
Reactome:R-DRE-1482925 Acyl chain remodelling of PG
Reactome:R-DRE-418346 Platelet homeostasis
Reactome:R-GGA-1483206 Glycerophospholipid biosynthesis
Reactome:R-GGA-1482798 Acyl chain remodeling of CL
Reactome:R-GGA-162582 Signaling Pathways
Reactome:R-GGA-112040 G-protein mediated events
Reactome:R-GGA-418346 Platelet homeostasis
Reactome:R-HSA-418346 Platelet homeostasis
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-2142753 Arachidonate metabolism
Reactome:R-HSA-8979227 Triglyceride metabolism
Reactome:R-HSA-1483206 Glycerophospholipid biosynthesis
Reactome:R-HSA-1482839 Acyl chain remodelling of PE
Reactome:R-HSA-1482788 Acyl chain remodelling of PC
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-HSA-388396 GPCR downstream signalling
Reactome:R-HSA-111885 Opioid Signalling
Reactome:R-HSA-111996 Ca-dependent events
Reactome:R-HSA-8953897 Cellular responses to stimuli
Reactome:R-HSA-6803157 Antimicrobial peptides
Reactome:R-MMU-2029485 Role of phospholipids in phagocytosis
Reactome:R-MMU-2142753 Arachidonate metabolism
Reactome:R-MMU-1483206 Glycerophospholipid biosynthesis
Reactome:R-MMU-1482839 Acyl chain remodelling of PE
Reactome:R-MMU-1482788 Acyl chain remodelling of PC
Reactome:R-MMU-109582 Hemostasis
Reactome:R-MMU-432142 Platelet sensitization by LDL
Reactome:R-MMU-392518 Signal amplification
Reactome:R-MMU-8953897 Cellular responses to stimuli
Reactome:R-MMU-2262752 Cellular responses to stress
Reactome:R-MMU-112040 G-protein mediated events
Reactome:R-RNO-1483257 Phospholipid metabolism
Reactome:R-RNO-1482801 Acyl chain remodelling of PS
Reactome:R-RNO-1482925 Acyl chain remodelling of PG
Reactome:R-RNO-418594 G alpha (i) signalling events
Reactome:R-RNO-112043 PLC beta mediated events
Reactome:R-RNO-76002 Platelet activation, signaling and aggregation
Reactome:R-RNO-418592 ADP signalling through P2Y purinoceptor 1
Reactome:R-RNO-6803157 Antimicrobial peptides
Reactome:R-SSC-3299685 Detoxification of Reactive Oxygen Species
Reactome:R-XTR-109582 Hemostasis
Reactome:R-XTR-432142 Platelet sensitization by LDL
Reactome:R-XTR-392518 Signal amplification
Reactome:R-XTR-1483206 Glycerophospholipid biosynthesis
Reactome:R-XTR-1482798 Acyl chain remodeling of CL
Reactome:R-XTR-162582 Signaling Pathways
Reactome:R-XTR-372790 Signaling by GPCR
Reactome:R-XTR-111995 phospho-PLA2 pathway
WikiPathways:WP5122 Prostaglandin and leukotriene metabolism in senescence
WikiPathways:WP5188 Retinol metabolism
WikiPathways:WP5321 Prostaglandin and leukotriene metabolism in senescence
WikiPathways:WP4746 Thyroid hormones production and peripheral downstream signaling effects
WikiPathways:WP2533 Glycerophospholipid biosynthetic pathway
PathBank:SMP0120730 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0000083 Acetylsalicylic Acid Action Pathway
PathBank:SMP0000087 Rofecoxib Action Pathway
PathBank:SMP0000094 Sulindac Action Pathway
PathBank:SMP0000104 Indomethacin Action Pathway
PathBank:SMP0000120 Naproxen Action Pathway
PathBank:SMP0000106 Meloxicam Action Pathway
PathBank:SMP0000693 Antrafenine Action Pathway
PathBank:SMP0000697 Flurbiprofen Action Pathway
PathBank:SMP0000701 Phenylbutazone Action Pathway
PathBank:SMP0000705 Tiaprofenic Acid Action Pathway
PathBank:SMP0000709 Salicylic Acid Action Pathway
PathBank:SMP0087322 Phospholipid Biosynthesis
PathBank:SMP0063652 Phospholipid Biosynthesis
PathBank:SMP0000075 Arachidonic Acid Metabolism
PathBank:SMP0000086 Ibuprofen Action Pathway
PathBank:SMP0000093 Diclofenac Action Pathway
PathBank:SMP0000098 Ketorolac Action Pathway
PathBank:SMP0000102 Bromfenac Action Pathway
PathBank:SMP0000114 Nabumetone Action Pathway
PathBank:SMP0000692 Antipyrine Action Pathway
PathBank:SMP0000696 Fenoprofen Action Pathway
PathBank:SMP0000700 Lornoxicam Action Pathway
PathBank:SMP0000704 Tolmetin Action Pathway
PathBank:SMP0000708 Salicylate-Sodium Action Pathway
PathBank:SMP0087353 Retinol Metabolism
PathBank:SMP0063595 Arachidonic Acid Metabolism
PathBank:SMP0120720 Vitamin A Deficiency
PathBank:SMP0121229 alpha-Linolenic Acid Metabolism
PathBank:SMP0000018 Alpha Linolenic Acid and Linoleic Acid Metabolism
PathBank:SMP0000025 Phospholipid Biosynthesis
PathBank:SMP0000077 Piroxicam Action Pathway
PathBank:SMP0000084 Etodolac Action Pathway
PathBank:SMP0000074 Retinol Metabolism
PathBank:SMP0000336 Vitamin A Deficiency
PathBank:SMP0000109 Mefenamic Acid Action Pathway
PathBank:SMP0000289 Diflunisal Action Pathway
PathBank:SMP0000116 Valdecoxib Action Pathway
PathBank:SMP0000358 Fc Epsilon Receptor I Signaling in Mast Cells
PathBank:SMP0000694 Carprofen Action Pathway
PathBank:SMP0000698 Magnesium Salicylate Action Pathway
PathBank:SMP0000702 Nepafenac Action Pathway
PathBank:SMP0000706 Tenoxicam Action Pathway
PathBank:SMP0000710 Acetaminophen Action Pathway
PathBank:SMP0087260 Retinol Metabolism
PathBank:SMP0120510 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0120901 GnRH Signaling Pathway
PathBank:SMP0120949 GnRH Signaling Pathway
PathBank:SMP0000353 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0000085 Ketoprofen Action Pathway
PathBank:SMP0000096 Celecoxib Action Pathway
PathBank:SMP0000101 Suprofen Action Pathway
PathBank:SMP0000113 Oxaprozin Action Pathway
PathBank:SMP0000695 Etoricoxib Action Pathway
PathBank:SMP0000699 Lumiracoxib Action Pathway
PathBank:SMP0000703 Trisalicylate-Choline Action Pathway
PathBank:SMP0000707 Salsalate Action Pathway
PathBank:SMP0087279 Alpha Linolenic Acid and Linoleic Acid Metabolism
PathBank:SMP0087315 Arachidonic Acid Metabolism
PathBank:SMP0063593 Alpha Linolenic Acid and Linoleic Acid Metabolism
PathBank:SMP0063811 GnRH Signaling Pathway