Retinol metabolism

Blaner WS, Prystowsky JH, Smith JE, Goodman DS. Rat liver retinyl palmitate hydrolase activity. Relationship to cholesteryl oleate and triolein hydrolase activities. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1984 Jul;794(3):419–27. doi: 10.1016/0005-2760(84)90008-0.

Metabolites

11-cis-Retinol

Formula: C20H30O (286.229653)

CAS ID: 22737-96-8

11-cis-Retinyl palmitate

Formula: C36H60O2 (524.459306)

CAS ID: 51249-33-3

9-cis-Retinal

Formula: C20H28O (284.2140038)

CAS ID: 514-85-2

9-cis-Retinol

Formula: C20H30O (286.229653)

CAS ID: 22737-97-9

all-trans-18-Hydroxyretinoic acid

Formula: C20H28O3 (316.2038338)

CAS ID: 63531-93-1

all-trans-4-Oxoretinoic acid

Formula: C20H26O3 (314.1881846)

CAS ID: 38030-57-8

beta-Carotene

Formula: C40H56 (536.4381776)

CAS ID: 7235-40-7

Retinal

Formula: C20H28O (284.2140038)

CAS ID: 116-31-4

Retinol

Formula: C20H30O (286.229653)

CAS ID: 68-26-8

retinoate

Formula: C20H27O2 (299.2010942)

CAS ID:



Enzyme

EC Number name full name note
1.14.14.-
1.1.1.1 alcohol dehydrogenase alcohol:NAD+ oxidoreductase
1.1.1.105 all-trans-retinol dehydrogenase (NAD+) all-trans retinol:NAD+ oxidoreductase
1.1.1.184 carbonyl reductase (NADPH) secondary-alcohol:NADP+ oxidoreductase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase 3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase
1.1.1.300 NADP-retinol dehydrogenase retinol:NADP+ oxidoreductase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase 3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase
1.13.11.63 beta-carotene 15,15'-dioxygenase beta-carotene:oxygen 15,15'-dioxygenase (bond-cleaving)
1.14.14.1 unspecific monooxygenase substrate,NADPH-hemoprotein reductase:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1.2.1.19 aminobutyraldehyde dehydrogenase 4-aminobutanal:NAD+ 1-oxidoreductase
1.2.1.28 benzaldehyde dehydrogenase (NAD+) benzaldehyde:NAD+ oxidoreductase
1.2.1.3 aldehyde dehydrogenase (NAD+) aldehyde:NAD+ oxidoreductase
1.2.1.36 retinal dehydrogenase retinal:NAD+ oxidoreductase
1.2.3.1 aldehyde oxidase aldehyde:oxygen oxidoreductase
2.3.1.135 phosphatidylcholine-retinol O-acyltransferase phosphatidylcholine:retinol---[cellular-retinol-binding-protein] O-acyltransferase
2.3.1.20 diacylglycerol O-acyltransferase acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase
2.3.1.75 long-chain-alcohol O-fatty-acyltransferase acyl-CoA:long-chain-alcohol O-acyltransferase
2.3.1.76 retinol O-fatty-acyltransferase acyl-CoA:retinol O-acyltransferase
3.1.1.3 triacylglycerol lipase triacylglycerol acylhydrolase
3.1.1.4 phospholipase A2 phosphatidylcholine 2-acylhydrolase
3.1.1.64 retinoid isomerohydrolase all-trans-retinyl ester acylhydrolase, 11-cis retinol forming
4.2.1.152 hydroperoxy icosatetraenoate dehydratase hydroperoxyicosatetraenoate hydro-lyase (oxoicosatetraenoate-forming)
5.3.3.22 lutein isomerase lutein DELTA4-DELTA5-isomerase


Proteins

Protein ID name full name