Platelet homeostasis

Bolego C, Buccellati C, Radaelli T, Cetin I, Puglisi L, Folco G, Sala A. eNOS, COX-2, and prostacyclin production are impaired in endothelial cells from diabetics. Biochemical and Biophysical Research Communications. 2006 Jan;339(1):188–90. doi: 10.1016/j.bbrc.2005.11.017.; Becker BF, Heindl B, Kupatt C, Zahler S. Endothelial function and hemostasis. Clinical Research in Cardiology. 2000 Mar;89(3):160–7. doi: 10.1007/pl00007320.

Metabolites

Acetate

Formula: C2H4O2 (60.0211284)

CAS ID: 64-19-7

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Nitric oxide

Formula: NO (29.997989)

CAS ID: 10102-43-9

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

L-argininium(1+)

Formula: C6H15N4O2 (175.119495)

CAS ID: 17806-42-7

PC O-18:0/2:0

Formula: C28H58NO7P (551.3950688)

CAS ID: 74389-69-8

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic GMP(1-)

Formula: C10H11N5O7P (344.0396086)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

1-octadecylglycero-3-phosphocholine

Formula: C26H56NO6P (509.38450460000007)

CAS ID: 72490-82-5



Enzyme

EC Number name full name note
2.7.10.2 non-specific protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
3.1.1.4 phospholipase A2 phosphatidylcholine 2-acylhydrolase
3.1.1.5 lysophospholipase 2-lysophosphatidylcholine acylhydrolase
3.1.3.48 protein-tyrosine-phosphatase protein-tyrosine-phosphate phosphohydrolase


Proteins

Protein ID name full name