Triglyceride catabolism

Brasaemle DL, Dolios G, Shapiro L, Wang R. Proteomic Analysis of Proteins Associated with Lipid Droplets of Basal and Lipolytically Stimulated 3T3-L1 Adipocytes. Journal of Biological Chemistry. 2004 Nov;279(45):46835–42. doi: 10.1074/jbc.m409340200.; Kraemer FB, Shen WJ. Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis. J Lipid Res. 2002 Oct;43(10):1585–94. doi: 10.1194/jlr.r200009-jlr200. PMID: 12364542.; Holm C, Osterlund T, Laurell H, Contreras JA. Molecular mechanisms regulating hormone-sensitive lipase and lipolysis. Annu Rev Nutr. 2000;20():365–93. doi: 10.1146/annurev.nutr.20.1.365. PMID: 10940339.

Metabolites

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

Glycerol

Formula: C3H8O3 (92.0473418)

CAS ID: 56-81-5

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Retinol

Formula: C20H30O (286.229653)

CAS ID: 68-26-8

Retinyl palmitate

Formula: C36H60O2 (524.459306)

CAS ID: 79-81-2

hexadecanoate

Formula: C16H31O2 (255.2323926)

CAS ID: 143-20-4

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

sn-glycerol 3-phosphate(2-)

Formula: C3H7O6P (169.9980252)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
1.1.5.3 glycerol-3-phosphate dehydrogenase sn-glycerol 3-phosphate:quinone oxidoreductase
2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase
3.1.1.23 acylglycerol lipase glycerol-ester acylhydrolase
3.1.1.3 triacylglycerol lipase triacylglycerol acylhydrolase
3.1.1.4 phospholipase A2 phosphatidylcholine 2-acylhydrolase
3.1.1.79 hormone-sensitive lipase diacylglycerol acylhydrolase


Proteins

Protein ID name full name