Cellular responses to stimuli

Kültz D. Molecular and evolutionary basis of the cellular stress response. Annu Rev Physiol. 2005;67():225–57. doi: 10.1146/annurev.physiol.67.040403.103635. PMID: 15709958.

Metabolites

Arsenic

Formula: As (74.921596)

CAS ID: 7440-38-2

Cadmium

Formula: Cd (113.903361)

CAS ID: 7440-43-9

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

CO

Formula: CO (27.994915)

CAS ID: 630-08-0

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

Cu+

Formula: Cu (62.929599)

CAS ID: 17493-86-6

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

Glutathione

Formula: C10H17N3O6S (307.08380220000004)

CAS ID: 70-18-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

HO-

Formula: OH (17.0027396)

CAS ID: 14280-30-9

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Hydroxyl radical

Formula: OH (17.0027396)

CAS ID: 3352-57-6

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Nicotinamide

Formula: C6H6N2O (122.0480106)

CAS ID: 98-92-0

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Progesterone

Formula: C21H30O2 (314.224568)

CAS ID: 57-83-0

Superoxide

Formula: O2 (31.98983)

CAS ID: 11062-77-4

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

L-argininium(1+)

Formula: C6H15N4O2 (175.119495)

CAS ID: 17806-42-7

biliverdin(2-)

Formula: C33H32N4O6 (580.2321732)

CAS ID: 114-25-0

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

nitrite

Formula: NO2 (45.992904)

CAS ID: 14797-65-0

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic AMP(1-)

Formula: C10H11N5O6P (328.0446936)

CAS ID: 62906-31-4

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.6.3.-
1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase glutathione:lipid-hydroperoxide oxidoreductase
1.11.1.2 NADPH peroxidase NADPH:hydrogen-peroxide oxidoreductase
1.11.1.24 thioredoxin-dependent peroxiredoxin thioredoxin:hydroperoxide oxidoreductase
1.11.1.27 glutathione-dependent peroxiredoxin glutathione:hydroperoxide oxidoreductase
1.11.1.6 catalase hydrogen-peroxide:hydrogen-peroxide oxidoreductase
1.11.1.9 glutathione peroxidase glutathione:hydrogen-peroxide oxidoreductase
1.14.14.18 heme oxygenase (biliverdin-producing) protoheme,NADPH-hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
1.8.1.9 thioredoxin-disulfide reductase thioredoxin:NADP+ oxidoreductase
1.8.3.2 thiol oxidase thiol:oxygen oxidoreductase
2.3.1.23 1-acylglycerophosphocholine O-acyltransferase acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase
2.3.2.23 E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
2.3.2.24 (E3-independent) E2 ubiquitin-conjugating enzyme S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:L-lysine ubiquitinyl transferase ([E3 ubiquitin transferase]-independent)
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.10.2 non-specific protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.10 IkappaB kinase ATP:[IkappaB protein] phosphotransferase
2.7.11.11 cAMP-dependent protein kinase ATP:protein Ser/Thr-phosphotransferase (3',5'-cAMP-dependent)
2.7.11.17 Ca2+/calmodulin-dependent protein kinase ATP:protein phosphotransferase (Ca2+/calmodulin-dependent)
2.7.11.22 cyclin-dependent kinase ATP:cyclin phosphotransferase
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)
3.1.1.4 phospholipase A2 phosphatidylcholine 2-acylhydrolase
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
3.4.22.53 calpain-2
3.4.24.85 S2P endopeptidase
3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase
3.6.4.10 non-chaperonin molecular chaperone ATPase ATP phosphohydrolase (polypeptide-polymerizing)
3.6.5.3 protein-synthesizing GTPase GTP phosphohydrolase (mRNA-translation-assisting)
7.6.2.2 ABC-type xenobiotic transporter ATP phosphohydrolase (ABC-type, xenobiotic-exporting)
7.6.2.3 ABC-type glutathione-S-conjugate transporter ATP + H2O + glutathione-S-conjugate[side 1] = ADP + phosphate + glutathione-S-conjugate[side 2]


Proteins

Protein ID name full name