Acyl chain remodelling of PI

Ghomashchi F, Naika GS, Bollinger JG, Aloulou A, Lehr M, Leslie CC, Gelb MH. Interfacial Kinetic and Binding Properties of Mammalian Group IVB Phospholipase A2 (cPLA2ß) and Comparison with the Other cPLA2 Isoforms. Journal of Biological Chemistry. 2010 Nov;285(46):36100–11. doi: 10.1074/jbc.m110.165647.; Gijón MA, Riekhof WR, Zarini S, Murphy RC, Voelker DR. Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils. Journal of Biological Chemistry. 2008 Oct;283(44):30235–45. doi: 10.1074/jbc.m806194200.; Lee HC, Inoue T, Imae R, Kono N, Shirae S, Matsuda S, Gengyo-Ando K, Mitani S, Arai H. Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol. Mol Biol Cell. 2008 Mar;19(3):1174–84. PMID: 18094042; PMCID: PMC2262980.; Singer AG, Ghomashchi F, Le Calvez C, Bollinger J, Bezzine S, Rouault M, Sadilek M, Nguyen E, Lazdunski M, Lambeau G, Gelb MH. Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2. Journal of Biological Chemistry. 2002 Dec;277(50):48535–49. doi: 10.1074/jbc.m205855200.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5



Enzyme

EC Number name full name note
2.3.1.-
3.1.1.4 phospholipase A2 phosphatidylcholine 2-acylhydrolase


Proteins

Protein ID name full name