Biological oxidations
Metabolites
(24S)-Cholest-5-ene-3beta,7alpha,24-triol
Formula: C27H46O3 (418.34467659999996)
CAS ID: 245523-67-5
1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide
Formula: C11H16N2O5 (256.1059166)
CAS ID: 19132-12-8
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Formula: C29H46O (410.3548466)
CAS ID: 64284-64-6
(24S)-1alpha,24,25-trihydroxyvitamin D3 / (24S)-1alpha,24,25-trihydroxycholecalciferol
Formula: C27H44O4 (432.3239424)
CAS ID: 56142-95-1
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.-.-.- | |||
| 1.1.1.1 | alcohol dehydrogenase | alcohol:NAD+ oxidoreductase | |
| 1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) | all-trans retinol:NAD+ oxidoreductase | |
| 1.1.1.184 | carbonyl reductase (NADPH) | secondary-alcohol:NADP+ oxidoreductase | |
| 1.1.1.19 | glucuronate reductase | L-gulonate:NADP+ 6-oxidoreductase | |
| 1.1.1.2 | alcohol dehydrogenase (NADP+) | alcohol:NADP+ oxidoreductase | |
| 1.1.1.20 | glucuronolactone reductase | L-gulono-1,4-lactone:NADP+ 1-oxidoreductase | |
| 1.1.1.22 | UDP-glucose 6-dehydrogenase | UDP-alpha-D-glucose:NAD+ 6-oxidoreductase | |
| 1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase | S-(hydroxymethyl)glutathione:NAD+ oxidoreductase | |
| 1.1.1.372 | D/L-glyceraldehyde reductase | glycerol:NADP+ oxidoreductase (D/L-glyceraldehyde-forming) | |
| 1.1.1.54 | allyl-alcohol dehydrogenase | allyl-alcohol:NADP+ oxidoreductase | |
| 1.1.1.66 | omega-hydroxydecanoate dehydrogenase | 10-hydroxydecanoate:NAD+ 10-oxidoreductase | |
| 1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) | 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase | |
| 1.14.13.148 | trimethylamine monooxygenase | N,N,N-trimethylamine,NADPH:oxygen oxidoreductase (N-oxide-forming) | |
| 1.14.13.32 | albendazole monooxygenase | albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming) | |
| 1.14.13.8 | flavin-containing monooxygenase | N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming) | |
| 1.14.14.1 | unspecific monooxygenase | substrate,NADPH-hemoprotein reductase:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing) | |
| 1.14.14.139 | 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase | 5beta-cholestane-3alpha,7alpha-diol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating) | |
| 1.14.14.14 | aromatase | testosterone monooxygenase (17beta-estradiol-forming) | |
| 1.14.14.154 | sterol 14alpha-demethylase | sterol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) | |
| 1.14.14.16 | steroid 21-monooxygenase | steroid,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) | |
| 1.14.14.177 | ultra-long-chain fatty acid omega-hydroxylase | ultra-long-chain fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating) | |
| 1.14.14.24 | vitamin D 25-hydroxylase | calciol,NADPH-hemoprotein reductase:oxygen oxidoreductase (25-hydroxylating) | |
| 1.14.14.25 | cholesterol 24-hydroxylase | cholesterol,NADPH-hemoprotein reductase:oxygen oxidoreductase (24-hydroxylating) | |
| 1.14.14.26 | 24-hydroxycholesterol 7alpha-hydroxylase | (24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) | |
| 1.14.14.55 | quinine 3-monooxygenase | quinine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase | |
| 1.14.14.56 | 1,8-cineole 2-exo-monooxygenase | 1,8-cineole,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating) | |
| 1.14.14.73 | albendazole monooxygenase (sulfoxide-forming) | albendazole,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming) | |
| 1.14.14.79 | docosahexaenoic acid omega-hydroxylase | docosahexaenoate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (22-hydroxydocosahexaenoate forming) | |
| 1.14.14.80 | long-chain fatty acid omega-monooxygenase | long-chain fatty acid,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating) | |
| 1.14.15.15 | cholestanetriol 26-monooxygenase | 5beta-cholestane-3alpha,7alpha,12alpha-triol,adrenodoxin:oxygen oxidoreductase (26-hydroxylating) | |
| 1.14.15.16 | vitamin D3 24-hydroxylase | calcitriol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating) | |
| 1.14.15.18 | calcidiol 1-monooxygenase | calcidiol,adrenodoxin:oxygen oxidoreductase (1-hydroxylating) | |
| 1.14.15.4 | steroid 11beta-monooxygenase | steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating) | |
| 1.14.15.5 | corticosterone 18-monooxygenase | corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating) | |
| 1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) | cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving) | |
| 1.14.99.1 | prostaglandin-endoperoxide synthase | (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase | |
| 1.16.1.8 | [methionine synthase] reductase | [methionine synthase]-methylcob(III)alamin,S-adenosyl-L-homocysteine:NADP+ oxidoreductase | |
| 1.18.1.6 | adrenodoxin-NADP+ reductase | adrenodoxin:NADP+ oxidoreductase | |
| 1.2.1.19 | aminobutyraldehyde dehydrogenase | 4-aminobutanal:NAD+ 1-oxidoreductase | |
| 1.2.1.28 | benzaldehyde dehydrogenase (NAD+) | benzaldehyde:NAD+ oxidoreductase | |
| 1.2.1.3 | aldehyde dehydrogenase (NAD+) | aldehyde:NAD+ oxidoreductase | |
| 1.2.1.36 | retinal dehydrogenase | retinal:NAD+ oxidoreductase | |
| 1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] | aldehyde:NAD(P)+ oxidoreductase | |
| 1.20.4.2 | methylarsonate reductase | glutathione:methylarsonate oxidoreductase | |
| 1.4.3.21 | primary-amine oxidase | primary-amine:oxygen oxidoreductase (deaminating) | |
| 1.4.3.22 | diamine oxidase | histamine:oxygen oxidoreductase (deaminating) | |
| 1.4.3.4 | monoamine oxidase | amine:oxygen oxidoreductase (deaminating) | |
| 1.5.3.13 | N1-acetylpolyamine oxidase | N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming) | |
| 1.6.2.2 | cytochrome-b5 reductase | NADH:ferricytochrome-b5 oxidoreductase | |
| 1.6.2.4 | NADPH-hemoprotein reductase | NADPH:hemoprotein oxidoreductase | |
| 1.6.5.10 | NADPH dehydrogenase (quinone) | NADPH:(quinone-acceptor) oxidoreductase | |
| 1.8.5.1 | glutathione dehydrogenase (ascorbate) | glutathione:dehydroascorbate oxidoreductase | |
| 2.1.1.1 | nicotinamide N-methyltransferase | S-adenosyl-L-methionine:nicotinamide N-methyltransferase | |
| 2.1.1.13 | methionine synthase | 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase | |
| 2.1.1.137 | arsenite methyltransferase | S-adenosyl-L-methionine:arsenous acid As-methyltransferase | |
| 2.1.1.6 | catechol O-methyltransferase | S-adenosyl-L-methionine:catechol O-methyltransferase | |
| 2.1.1.67 | thiopurine S-methyltransferase | S-adenosyl-L-methionine:thiopurine S-methyltransferase | |
| 2.3.1.118 | N-hydroxyarylamine O-acetyltransferase | acetyl-CoA:N-hydroxyarylamine O-acetyltransferase | |
| 2.3.1.48 | histone acetyltransferase | acetyl-CoA:[protein]-L-lysine acetyltransferase | |
| 2.3.1.5 | arylamine N-acetyltransferase | acetyl-CoA:arylamine N-acetyltransferase | |
| 2.3.2.2 | gamma-glutamyltransferase | (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase | |
| 2.4.1.17 | glucuronosyltransferase | UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) | |
| 2.5.1.18 | glutathione transferase | RX:glutathione R-transferase | |
| 2.5.1.6 | methionine adenosyltransferase | ATP:L-methionine S-adenosyltransferase | |
| 2.7.7.9 | UTP-glucose-1-phosphate uridylyltransferase | UTP:alpha-D-glucose-1-phosphate uridylyltransferase | |
| 2.8.2.1 | aryl sulfotransferase | 3'-phosphoadenylyl-sulfate:phenol sulfotransferase | |
| 2.8.2.14 | bile-salt sulfotransferase | 3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase | |
| 2.8.2.2 | alcohol sulfotransferase | 3'-phosphoadenylyl-sulfate:alcohol sulfotransferase | |
| 2.8.2.4 | estrone sulfotransferase | 3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase | |
| 3.1.1.1 | carboxylesterase | carboxylic-ester hydrolase | |
| 3.1.1.3 | triacylglycerol lipase | triacylglycerol acylhydrolase | |
| 3.1.1.56 | methylumbelliferyl-acetate deacetylase | 4-methylumbelliferyl-acetate acylhydrolase | |
| 3.1.1.93 | mycophenolic acid acyl-glucuronide esterase | mycophenolic acid O-acyl-glucuronide-ester hydrolase | |
| 3.1.2.12 | S-formylglutathione hydrolase | S-formylglutathione hydrolase | |
| 3.1.2.22 | palmitoyl[protein] hydrolase | palmitoyl[protein] hydrolase | |
| 3.1.3.57 | inositol-1,4-bisphosphate 1-phosphatase | 1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase | |
| 3.1.3.7 | 3'(2'),5'-bisphosphate nucleotidase | adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase | |
| 3.13.2.1 | adenosylhomocysteinase | S-adenosyl-L-homocysteine hydrolase | |
| 3.3.2.9 | microsomal epoxide hydrolase | cis-stilbene-oxide hydrolase | |
| 3.4.13.18 | cytosol nonspecific dipeptidase | ||
| 3.4.13.19 | membrane dipeptidase | ||
| 3.4.19.13 | glutathione gamma-glutamate hydrolase | ||
| 3.4.19.14 | leukotriene-C4 hydrolase | ||
| 3.5.1.114 | N-acyl-aromatic-L-amino acid amidohydrolase | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | |
| 3.5.1.14 | N-acyl-aliphatic-L-amino acid amidohydrolase | N-acyl-aliphatic-L-amino acid amidohydrolase (carboxylate-forming) | |
| 3.5.2.6 | beta-lactamase | beta-lactam hydrolase | |
| 3.5.2.9 | 5-oxoprolinase (ATP-hydrolysing) | 5-oxo-L-proline amidohydrolase (ATP-hydrolysing) | |
| 4.1.1.35 | UDP-glucuronate decarboxylase | UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming) | |
| 4.2.1.152 | hydroperoxy icosatetraenoate dehydratase | hydroperoxyicosatetraenoate hydro-lyase (oxoicosatetraenoate-forming) | |
| 4.3.2.9 | gamma-glutamylcyclotransferase | alpha-(gamma-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxo-L-proline producing) | |
| 4.4.1.20 | leukotriene-C4 synthase | leukotriene-C4 glutathione-lyase (leukotriene-A4-forming) | |
| 5.2.1.2 | maleylacetoacetate isomerase | 4-maleylacetoacetate cis-trans-isomerase | |
| 5.3.99.2 | Prostaglandin-D synthase | (5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase | |
| 5.3.99.3 | prostaglandin-E synthase | (5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase | |
| 5.3.99.5 | thromboxane-A synthase | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase | |
| 6.2.1.1 | acetate-CoA ligase | acetate:CoA ligase (AMP-forming) | |
| 6.2.1.17 | propionate-CoA ligase | propanoate:CoA ligase (AMP-forming) | |
| 6.3.2.2 | glutamate-cysteine ligase | L-glutamate:L-cysteine gamma-ligase (ADP-forming) | |
| 6.3.2.3 | glutathione synthase | gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming) |
Proteins
| Protein ID | name | full name |
|---|