Phenyl acetate (BioCAD00000016155)

feces

Metabolite Card

Formula: C8H8O2 (136.0524)
SMILES: CC(=O)OC1=CC=CC=C1

Synonyms [en]

Phenyl acetate; acetylphenol; Phenol acetate; acetic acid,phenyl ester; Acetates; PhOAc

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Phenyl acetate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000016155). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Phenol acetate appears as a clear colorless liquid with a sweetish solvent odor. Difficult to ignite. Used as a laboratory reagent and in the production of some organic chemicals. Phenyl acetate is an acetate ester obtained by the formal condensation of phenol with acetic acid. It is a member of phenyl acetates and a member of benzenes. It is functionally related to a phenol. Phenyl acetate is a natural product found in Arabidopsis thaliana and Euglena gracilis with data available. Phenyl Acetate is an aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibition, and apoptosis in tumor cells. Implicated mechanisms of action include decreased protein prenylation, activation of the peroxisome proliferation-activated receptors, inhibition of DNA methylation, and depletion of glutamine. (NCI04) Phenyl acetate is a metabolite found in or produced by Saccharomyces cerevisiae.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 122-79-2
  • PubChem: 31229
  • ChEBI: ChEBI:8082
  • HMDB: HMDB0040733
  • KEGG: C00548
  • BioCyc: CPD-22363
  • NCBI MeSH: phenyl acetate
  • Wikipedia: Phenyl_acetate
  • RefMet: RM0136710
  • MoNA: HMDB0040733_c_ms_102184
  • MoNA: HMDB0040733_c_ms_102185
  • MoNA: HMDB0040733_c_ms_102186
  • MoNA: HMDB0040733_c_ms_102187
  • MoNA: HMDB0040733_c_ms_102188
  • MoNA: HMDB0040733_c_ms_102189
  • MoNA: JP001311
  • MoNA: JP001532
  • MoNA: JP004944
  • MoNA: JP005897
  • MoNA: JP005960
  • MoNA: JP006896
  • Metlin: METLIN_65519
  • Coconut NaturalProduct: CNP0333279.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01241 3.1.1.2 phenyl acetate acetylhydrolase
KEGG:R07342 3.1.1.2 aryl-ester hydrolase
BioCyc:RXN-20743 3.1.1.2 CPD-22363 + WATER --> PHENOL + ACET + PROTON
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-GGA-177162 Conjugation of phenylacetate with glutamine
Reactome:R-XTR-177162 Conjugation of phenylacetate with glutamine
Reactome:R-GGA-156587 Amino Acid conjugation
Reactome:R-XTR-156587 Amino Acid conjugation
Reactome:R-GGA-159424 Conjugation of carboxylic acids
Reactome:R-DRE-177162 Conjugation of phenylacetate with glutamine
Reactome:R-XTR-159424 Conjugation of carboxylic acids
Reactome:R-BTA-1430728 Metabolism
Reactome:R-CFA-1430728 Metabolism
Reactome:R-CFA-156580 Phase II - Conjugation of compounds
Reactome:R-CFA-159424 Conjugation of carboxylic acids
Reactome:R-GGA-156580 Phase II - Conjugation of compounds
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-159424 Conjugation of carboxylic acids
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-159424 Conjugation of carboxylic acids
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-BTA-159424 Conjugation of carboxylic acids
Reactome:R-CFA-156587 Amino Acid conjugation
View All Pathways