3-Acetamidopropanal (BioCAD00000003346)

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Metabolite Card

Formula: C5H9NO2 (115.0633)
SMILES: CC(=O)NCCC=O

Synonyms [en]

3-acetamidopropanal; N-(3-oxopropyl)acetamide; Acetamidopropanal; 33J3W58CHU; 3AAP; 3-acetamidopropionaldehyde

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Acetamidopropanal. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000003346). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Acetamidopropanal is associated with urea cycle and metabolism of arginine, proline, glutamate, aspartate and asparagine. Induction of SSAT typically gives rise to growth inhibition or apoptosis, depending upon the cell type and the extent of enzyme overexpression. In such experiments, growth inhibition has been closely linked to depletion of intracellular polyamine pools ( 12) and disturbances in polyamine metabolism ( 13), whereas apoptosis has been associated with downstream events emanating from polyamine oxidase-mediated oxidation of acetylated polyamines and the associated release of oxidatively reactive by-products such as hydrogen peroxide and the aldehyde, 3-acetamidopropanal.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 73323-68-9
  • PubChem: 5460495
  • ChEBI: ChEBI:30322
  • HMDB: HMDB0012880
  • KEGG: C18170
  • BioCyc: CPD-10687
  • RefMet: RM0136396
  • Metlin: METLIN_72070
  • Coconut NaturalProduct: CNP0100556.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R03899 1.5.3.13 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming)
KEGG:R09074 1.5.3.13 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming)
Rhea:RHEA:25801 1.5.3.13 N1-acetylspermine + O2 + H2O => 3-acetamidopropanal + spermidine + H2O2
Rhea:RHEA:25802 1.5.3.13 3-acetamidopropanal + spermidine + H2O2 => N1-acetylspermine + O2 + H2O
Rhea:RHEA:25803 1.5.3.13 N1-acetylspermine + O2 + H2O <=> 3-acetamidopropanal + spermidine + H2O2
Rhea:RHEA:25813 1.5.3.13 N1-acetylspermidine + O2 + H2O => 3-acetamidopropanal + putrescine + H2O2
Rhea:RHEA:25814 1.5.3.13 3-acetamidopropanal + putrescine + H2O2 => N1-acetylspermidine + O2 + H2O
Rhea:RHEA:25815 1.5.3.13 N1-acetylspermidine + O2 + H2O <=> 3-acetamidopropanal + putrescine + H2O2
Rhea:RHEA:25869 1.5.3.13 N1,N12-diacetylspermine + O2 + H2O => 3-acetamidopropanal + N1-acetylspermidine + H2O2
Rhea:RHEA:25870 1.5.3.13 3-acetamidopropanal + N1-acetylspermidine + H2O2 => N1,N12-diacetylspermine + O2 + H2O
Rhea:RHEA:25871 1.5.3.13 N1,N12-diacetylspermine + O2 + H2O <=> 3-acetamidopropanal + N1-acetylspermidine + H2O2
BioCyc:RXN-12091 1.5.3.13 CPD-568 + OXYGEN-MOLECULE + WATER --> PUTRESCINE + CPD-10687 + HYDROGEN-PEROXIDE
BioCyc:RXN-9940 1.5.3.13 N1-ACETYLSPERMINE + OXYGEN-MOLECULE + WATER --> SPERMIDINE + CPD-10687 + HYDROGEN-PEROXIDE
BioCyc:RXN-10460 1.5.3.13 CPD-11268 + OXYGEN-MOLECULE + WATER --> CPD-568 + CPD-10687 + HYDROGEN-PEROXIDE
BioCyc:RXN-12090 1.5.3.17 N1-ACETYLSPERMINE + OXYGEN-MOLECULE + WATER --> SPERMIDINE + CPD-10687 + HYDROGEN-PEROXIDE
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Organism Source

Taxonomy Source

  1. Citrullus lanatus [ncbi taxid: 3654]

Pathway Synthetic

pathway id name
BioCyc:THAPS_PWY-6117 spermine and spermidine degradation I
BioCyc:HUMAN_PWY-6117 spermine and spermidine degradation I
BioCyc:META_PWY-6117 spermine and spermidine degradation I
BioCyc:PCHR_PWY-6117 spermine and spermidine degradation I
PlantCyc:POTATO_PWY-6117 spermine and spermidine degradation I
PlantCyc:SFALLAX_PWY-6117 spermine and spermidine degradation I
PlantCyc:OILPALM_PWY-6117 spermine and spermidine degradation I
PlantCyc:FVESCA_VESCA_PWY-6117 spermine and spermidine degradation I
PlantCyc:BARLEY_PWY-6117 spermine and spermidine degradation I
PlantCyc:CACUMINATA_PWY-6117 spermine and spermidine degradation I
PlantCyc:CASSAVA_PWY-6117 spermine and spermidine degradation I
PlantCyc:CHLAMY_PWY-6117 spermine and spermidine degradation I
PlantCyc:BOLERACEA_CAPITATA_PWY-6117 spermine and spermidine degradation I
PlantCyc:CCAMPESTRIS_PWY-6117 spermine and spermidine degradation I
PlantCyc:CCAPSULARIS_PWY-6117 spermine and spermidine degradation I
PlantCyc:CGRANDIFLORA_PWY-6117 spermine and spermidine degradation I
PlantCyc:VALLEYOAK_PWY-6117 spermine and spermidine degradation I
PlantCyc:ZMARINA_PWY-6117 spermine and spermidine degradation I
PlantCyc:POPLAR_PWY-6117 spermine and spermidine degradation I
PlantCyc:TOMATO_PWY-6117 spermine and spermidine degradation I
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