EC: 2.3.1.5

arylamine N-acetyltransferase (acetyl-CoA:arylamine N-acetyltransferase)

enzyme lambda metabolic reaction experiment
- [arylamine N-acetyltransferase(Enzyme) wildtype]

Acetyl_CoA + 2_Aminofluorene -> 2_Acetamidofluorene + Coenzyme_A		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 0.2 mM EDTA, 2 mM DTT, 15 mM acetylcarnitine, 2 U/ml carnitine acetyl-transferase
PH: 7.5
Temperature: 37
- [arylamine N-acetyltransferase(Enzyme) wildtype]

Acetyl_CoA + 2_Aminofluorene -> Coenzyme_A + 2_Acetamidofluorene		 (( (Vmax * S) ) / (Km + S)) buffer: RPMI-1640, 10% fetal bovine serum
PH: 7
Temperature: 37

Pathways

pathway id name
Reactome:R-BTA-9748784 Drug ADME
Reactome:R-BTA-9753281 APAP ADME
Reactome:R-BTA-1430728 Metabolism
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-HSA-156580 Phase II - Conjugation of compounds
Reactome:R-HSA-156582 Acetylation
Reactome:R-MMU-156580 Phase II - Conjugation of compounds
Reactome:R-MMU-156582 Acetylation
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-RNO-1430728 Metabolism
Reactome:R-BTA-156580 Phase II - Conjugation of compounds
Reactome:R-BTA-156582 Acetylation
Reactome:R-HSA-1430728 Metabolism
Reactome:R-RNO-156580 Phase II - Conjugation of compounds
Reactome:R-RNO-156582 Acetylation
PathBank:SMP0000028 Caffeine Metabolism
PathBank:SMP0087186 Caffeine Metabolism