Olmesartan medoxomil (BioCAD00000183848)

blood

Metabolite Card

Formula: C29H30N6O6 (558.2227)
SMILES: CCCC1=NC(=C(N1CC1=CC=C(C=C1)C1=C(C=CC=C1)C1=NN=NN1)C(=O)OCC1=C(C)OC(=O)O1)C(C)(C)O

Synonyms [en]

olmesartan medoxomil; Olmetec; Olmesartan medoxomil (Benicar); Benicar; KBio2_007626; Spectrum3_001676

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Olmesartan medoxomil. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000183848). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Olmesartan medoxomil is a member of biphenyls. Olmesartan Medoxomil is a synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion. An ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to manage HYPERTENSION. See also: Olmesartan (has active moiety); Amlodipine Besylate; Olmesartan Medoxomil (component of); Hydrochlorothiazide; olmesartan medoxomil (component of) ... View More ...

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1112046-13-5 (3HCl)
  • CAS Registry Number: 144689-63-4
  • PubChem: 130881
  • ChEBI: ChEBI:31932
  • HMDB: HMDB0255956
  • NCBI MeSH: Olmesartan Medoxomil
  • DrugBank: DBSALT001815
  • MoNA: CCMSLIB00000078195
  • MoNA: UPA00016
  • Metlin: METLIN_43884
  • Coconut NaturalProduct: CNP0469722.0

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-211945 Phase I - Functionalization of compounds
Reactome:R-CFA-1430728 Metabolism
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-RNO-211945 Phase I - Functionalization of compounds
Reactome:R-SSC-211945 Phase I - Functionalization of compounds
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-DRE-211945 Phase I - Functionalization of compounds
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-SSC-1430728 Metabolism
Reactome:R-SSC-211859 Biological oxidations
Reactome:R-XTR-211945 Phase I - Functionalization of compounds
Reactome:R-CFA-211859 Biological oxidations
Reactome:R-DRE-1430728 Metabolism
Reactome:R-GGA-1430728 Metabolism
Reactome:R-GGA-211859 Biological oxidations
Reactome:R-HSA-211945 Phase I - Functionalization of compounds
Reactome:R-MMU-211945 Phase I - Functionalization of compounds
View All Pathways