EC: 1.14.14.139

5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase (5beta-cholestane-3alpha,7alpha-diol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating))

enzyme lambda metabolic reaction experiment

Pathways

pathway id name
BioCyc:MOUSE_PWY-6061 bile acid biosynthesis, neutral pathway
Reactome:R-HSA-194068 Bile acid and bile salt metabolism
Reactome:R-HSA-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-211994 Sterols are 12-hydroxylated by CYP8B1
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-8957322 Metabolism of steroids
Reactome:R-MMU-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-211994 Sterols are 12-hydroxylated by CYP8B1
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Reactome:R-HSA-211976 Endogenous sterols
Reactome:R-MMU-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome:R-MMU-211976 Endogenous sterols
Reactome:R-HSA-192105 Synthesis of bile acids and bile salts
Reactome:R-HSA-211945 Phase I - Functionalization of compounds
Reactome:R-MMU-194068 Bile acid and bile salt metabolism
Reactome:R-MMU-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Reactome:R-MMU-211945 Phase I - Functionalization of compounds
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-8957322 Metabolism of steroids
Reactome:R-HSA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Reactome:R-HSA-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-MMU-192105 Synthesis of bile acids and bile salts
Reactome:R-MMU-211897 Cytochrome P450 - arranged by substrate type
PathBank:SMP0120468 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0000318 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120463 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120467 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120495 Zellweger Syndrome
PathBank:SMP0000035 Bile Acid Biosynthesis
PathBank:SMP0000314 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0000315 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120652 27-Hydroxylase Deficiency
PathBank:SMP0120477 Familial Hypercholanemia (FHCA)
PathBank:SMP0000317 Familial Hypercholanemia (FHCA)
PathBank:SMP0000316 Zellweger Syndrome
PathBank:SMP0000720 27-Hydroxylase Deficiency
PathBank:SMP0063601 Bile Acid Biosynthesis