EC: 1.14.14.1

unspecific monooxygenase (substrate,NADPH-hemoprotein reductase:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing))

enzyme lambda metabolic reaction experiment
uniprot:P98187 [unspecific monooxygenase(Enzyme) wildtype CYP4F8]

NADPH + O2 + H+ + 9,11_Epoxymethano_prostaglandin_H2 -> 19_Hydroxy_(9,11_epoxymethano)_prostaglandin_H2 + NADP+ + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 0.1 M KHPO4, 2 mM EDTA
PH: 7.4
Temperature: 37
uniprot:P11511 [2,2-Dimethylandrost-4-ene-3,17-dione]

3 NADPH + Androst_4_ene_3,17_dione + 3 O2 + 3 H+ -> Estrone + Formate + 3 NADP+ + 4 H2O		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2alpha-Methyl-19-hydroxyandrost-4-ene-3,17-dione]

3 O2 + 3 H+ + Androst_4_ene_3,17_dione + 3 NADPH -> Formate + Estrone + 3 NADP+ + 4 H2O		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2alpha-Methyl-19-oxoandrost-4-ene-3,17-dione]

3 NADPH + Androst_4_ene_3,17_dione + 3 H+ + 3 O2 -> Estrone + 4 H2O + 3 NADP+ + Formate		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2,2-Dimethyl-19-hydroxyandrost-4-ene-3,17-dione]

3 H+ + 3 NADPH + 3 O2 + Androst_4_ene_3,17_dione -> 4 H2O + 3 NADP+ + Estrone + Formate		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2,2-Dimethyl-19-oxoandrost-4-ene-3,17-dione]

3 O2 + 3 H+ + Androst_4_ene_3,17_dione + 3 NADPH -> 3 NADP+ + 4 H2O + Estrone + Formate		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2alpha-Methylandrost-4-ene-3,17-dione]

Androst_4_ene_3,17_dione + 3 O2 + 3 H+ + 3 NADPH -> Estrone + 4 H2O + 3 NADP+ + Formate		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2beta-Methylandrost-4-ene-3,17-dione]

3 H+ + 3 NADPH + 3 O2 + Androst_4_ene_3,17_dione -> Estrone + 3 NADP+ + Formate + 4 H2O		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [2-Methylene-androst-4-ene-3,17-dione]

Androst_4_ene_3,17_dione + 3 O2 + 3 H+ + 3 NADPH -> Formate + Estrone + 3 NADP+ + 4 H2O		 (( (Vmax * S) ) / (( (Km * (1 + (I / Ki))) ) + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype]

Androst_4_ene_3,17_dione + 3 O2 + 3 NADPH + 3 H+ -> Estrone + 3 NADP+ + 4 H2O + Formate		 (( (Vmax * S) ) / (Km + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + H+ + 2alpha_Methyl_19_oxoandrost_4_ene_3,17_dione + O2 -> 2_Methylestrone + NADP+ + H2O + Formate		 (( (Vmax * S) ) / (Km + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype]

2alpha_Methylandrost_4_ene_3,17_dione + O2 + NADPH + H+ -> 2alpha_Methyl_19_hydroxyandrost_4_ene_3,17_dione + H2O + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype]

2alpha_Methyl_19_hydroxyandrost_4_ene_3,17_dione + NADPH + H+ -> 2alpha_Methyl_19_oxoandrost_4_ene_3,17_dione + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 67 mM Phosphate
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GSVN]

H+ + O2 + Benzo[a]pyrene_7,8_diol + NADPH -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GSLS]

H+ + O2 + NADPH + Benzo[a]pyrene_7,8_diol -> H2O + NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GSLN]

H+ + Benzo[a]pyrene_7,8_diol + O2 + NADPH -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RSVN]

NADPH + Benzo[a]pyrene_7,8_diol + H+ + O2 -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RSLN]

Benzo[a]pyrene_7,8_diol + H+ + NADPH + O2 -> NADP+ + H2O + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RSLS]

H+ + O2 + NADPH + Benzo[a]pyrene_7,8_diol -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GSVS]

O2 + Benzo[a]pyrene_7,8_diol + NADPH + H+ -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + NADP+ + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RALS]

H+ + NADPH + O2 + Benzo[a]pyrene_7,8_diol -> NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RSVS]

H+ + Benzo[a]pyrene_7,8_diol + O2 + NADPH -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GSVN]

Benzo[a]pyrene_7,8_diol + O2 + H+ + NADPH -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RAVS]

NADPH + O2 + Benzo[a]pyrene_7,8_diol + H+ -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RAVN]

O2 + H+ + NADPH + Benzo[a]pyrene_7,8_diol -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RALN]

Benzo[a]pyrene_7,8_diol + NADPH + H+ + O2 -> NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RALN]

H+ + O2 + NADPH + Benzo[a]pyrene_7,8_diol -> NADP+ + H2O + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RAVS]

Benzo[a]pyrene_7,8_diol + O2 + NADPH + H+ -> NADP+ + H2O + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RALS]

H+ + Benzo[a]pyrene_7,8_diol + O2 + NADPH -> H2O + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RAVN]

H+ + Benzo[a]pyrene_7,8_diol + NADPH + O2 -> H2O + NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GALN]

H+ + O2 + Benzo[a]pyrene_7,8_diol + NADPH -> H2O + NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant RSVN]

NADPH + Benzo[a]pyrene_7,8_diol + H+ + O2 -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GALS]

O2 + NADPH + H+ + Benzo[a]pyrene_7,8_diol -> H2O + NADP+ + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GAVN]

NADPH + Benzo[a]pyrene_7,8_diol + H+ + O2 -> H2O + Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype allelic variant GAVS]

NADPH + H+ + Benzo[a]pyrene_7,8_diol + O2 -> Benzo[a]pyrene_7,8_dihydrodiol_9,10_oxide + NADP+ + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM NaPO4, 5 mM MgCl2
PH: 7.5
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype isoenzym CYP19A1]

3 H+ + 3 NADPH + 3 O2 + Androst_4_ene_3,17_dione -> 3 NADP+ + Estrone + Formate + 4 H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 67 mM Phosphate
PH: 7.4
Temperature: 37
- [Mg2+]

H+ + O2 + NADPH + Fenthion -> Fenthion_sulfoxide + H2O + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

H+ + NADPH + O2 + Fenthion -> Fenthion_sulfoxide + NADP+ + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

Fenthion + NADPH + O2 + H+ -> H2O + NADP+ + Fenthion_sulfoxide		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

Fenthion + H+ + NADPH + O2 -> H2O + Fenthion_sulfoxide + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

NADPH + O2 + H+ + Fenthion -> NADP+ + H2O + Fenthion_sulfoxide		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Bisdesoxyolaquindox + O2 -> Bisdesoxyolaquindox_2'_carboxyl_acid + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 0.05 M Tris-HCl, 2 mM NADP, 10 mM Glucose 6-phosphate, 1.6 U/ml glucose 6-phosphate dehydrogenase, 5 mM MgCl2
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + 7_Ethoxyresorufin + NADPH -> Ethanol + Resorufin + NADP+		 (( (( (Vmax_1 * S) ) / (Km_1 + S)) ) + (( (Vmax_2 * S) ) / (Km_2 + S))) buffer: 50 mM phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + 7_Ethoxyresorufin + O2 + H+ -> Resorufin + NADP+ + Ethanol		 (( (( (Vmax_1 * S) ) / (Km_1 + S)) ) + (( (Vmax_2 * S) ) / (Km_2 + S))) buffer: 50 mM phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

7_Methoxyresorufin + NADPH + H+ + O2 -> Resorufin + NADP+ + Methanol		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM phosphate
PH: 7.4
Temperature: 37
uniprot:Q9PU44 [unspecific monooxygenase(Enzyme) wildtype]

O2 + T_2_Toxin + NADPH -> 3'_Hydroxylated_T2_Toxin + H2O + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 0.1 M Potassium phosphate, 30 mM MgCl2
PH: 7.4
Temperature: 37
uniprot:Q9PU44 [unspecific monooxygenase(Enzyme) wildtype]

O2 + Erythromycin -> H2O + Formaldehyde + N_Demethyl_erythromycin		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Hepes, 30 mM MgCl2
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + Testosterone + H+ -> 6beta_Hydroxytestosterone + H2O + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + H+ + 7_Ethoxyresorufin + NADPH -> Resorufin + Ethanol + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + NADPH + Bufuralol -> H2O + NADP+ + 1_Hydroxy_bufuralol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

7_Methoxyresorufin + O2 + H+ + NADPH -> NADP+ + Resorufin + Methanol		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Tolbutamide + O2 + NADPH + H+ -> Hydroxytolbutamide + H2O + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Tolbutamide + NADPH + O2 + H+ -> H2O + Hydroxytolbutamide + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Testosterone + H+ + O2 -> H2O + NADP+ + 6beta_Hydroxytestosterone		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + NADPH + 7_Ethoxyresorufin -> Resorufin + Ethanol + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Bufuralol + H+ + O2 -> H2O + 1_Hydroxy_bufuralol + NADP+		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM phosphate, 5 mM MgCl2, 5 mM glucose 6-phosphate, 1.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:Q1PCR1 [unspecific monooxygenase(Enzyme) wildtype]

Aflatoxin_B1 + H+ + NADPH + O2 -> NADP+ + Aflatoxin_Q1 + H2O		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose, 3.2 mg/ml butylated hydroxyanisole-induced mouse cytosol, 5 mM GSH
PH: 7.6
Temperature: 37
uniprot:Q1PCR1 [unspecific monooxygenase(Enzyme) wildtype]

Aflatoxin_B1 + H+ + O2 + NADPH -> NADP+ + exo_Aflatoxin_B1_8,9_epoxide + H2O		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose, 3.2 mg/ml butylated hydroxyanisole-induced mouse cytosol, 5 mM GSH
PH: 7.6
Temperature: 37
uniprot:Q1PCR1 [unspecific monooxygenase(Enzyme) wildtype]

Nifedipine + NADPH + O2 + H+ -> H2O + NADP+ + Oxidized_nifedipine		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM potassium phosphate, 2 mM NADP, 5 mM glucose 6-phosphate, 0.5 U/ml glucose 6-phosphate dehydrogenase
PH: 7.6
Temperature: 37
- [Mg2+]

Fenthion + H+ + NADPH + O2 -> Fenthion_oxon + H2O + NADP+ + Sulfur		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

NADPH + Fenthion + O2 + H+ -> Fenthion_oxon + NADP+ + Sulfur + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

O2 + NADPH + Fenthion + H+ -> Fenthion_oxon + Sulfur + NADP+ + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
- [Mg2+]

NADPH + H+ + O2 + Fenthion -> NADP+ + Fenthion_oxon + Sulfur + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 1 mM EDTA, 2 mM glucose-6-phosphate, 2-4 U/ml G6PDH
PH: 7.4
Temperature: 37
uniprot:P79760 [unspecific monooxygenase(Enzyme) wildtype]

O2 + H+ + 7_Ethoxyresorufin + NADPH -> Ethanol + Resorufin + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P79761 [unspecific monooxygenase(Enzyme) wildtype]

7_Ethoxyresorufin + O2 + H+ + NADPH -> Resorufin + NADP+ + Ethanol		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P79760 [unspecific monooxygenase(Enzyme) wildtype]

7_Benzyloxyresorufin + NADPH + O2 + H+ -> Resorufin + Benzaldehyde + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P79761 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + 7_Benzyloxyresorufin + H+ -> Benzaldehyde + Resorufin + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P79761 [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + NADPH + 7_Methoxyresorufin -> Resorufin + Methanol + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P79760 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + 7_Methoxyresorufin + O2 + H+ -> NADP+ + Methanol + Resorufin		 (( (Vmax * A) ) / (Km_A + A)) buffer: 50 mM Tris-HCl, 25 mM MgCl2, 50 nM NADPH-cytochrome P450 reductase, 0.5% DMSO
PH: 7.5
Temperature: 37
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

H+ + NADPH + O2 + Aflatoxin_B1 -> NADP+ + Aflatoxin_B1_8,9_epoxide + H2O		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

Aflatoxin_B1 + O2 + NADPH + H+ -> Aflatoxin_Q1 + NADP+ + H2O		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

Aflatoxin_B1 + O2 + NADPH + H+ -> NADP+ + Aflatoxin_Q1 + H2O		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

O2 + Aflatoxin_B1 + H+ + NADPH -> NADP+ + H2O + Aflatoxin_B1_8,9_epoxide		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

Aflatoxin_B1 + O2 + H+ + NADPH -> Aflatoxin_B1_8,9_epoxide + NADP+ + H2O		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

O2 + Aflatoxin_B1 + H+ + NADPH -> Aflatoxin_B1_8,9_epoxide + H2O + NADP+		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

H+ + NADPH + Aflatoxin_B1 + O2 -> H2O + Aflatoxin_B1_8,9_epoxide + NADP+		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
- [unspecific monooxygenase(Enzyme) wildtype CYP2B-like]

O2 + Nicotine + NADPH + H+ -> 2 H+ + NADP+ + H2O + Cotinine		 (( (Vmax * A) ) / (Km + B)) buffer: 50 mM Tris-HCl
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

H+ + Aflatoxin_B1 + NADPH + O2 -> exo_Aflatoxin_B1_8,9_epoxide + NADP+ + H2O		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
uniprot:Q1PCR1 [unspecific monooxygenase(Enzyme) wildtype P450 3A37]

O2 + NADPH + H+ + Aflatoxin_B1 -> Aflatoxin_Q1 + NADP+ + H2O		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Aflatoxin_B1 + NADPH + H+ + O2 -> NADP+ + H2O + Aflatoxin_Q1		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
uniprot:Q1PCR1 [unspecific monooxygenase(Enzyme) wildtype P450 3A37]

H+ + Aflatoxin_B1 + O2 + NADPH -> NADP+ + exo_Aflatoxin_B1_8,9_epoxide + H2O		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
uniprot:G1MUB3 [unspecific monooxygenase(Enzyme) wildtype P450 1A5]

H+ + Aflatoxin_B1 + NADPH + O2 -> exo_Aflatoxin_B1_8,9_epoxide + H2O + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
uniprot:G1MUB3 [unspecific monooxygenase(Enzyme) wildtype P450 1A5]

NADPH + O2 + H+ + Aflatoxin_B1 -> NADP+ + H2O + Aflatoxin_M1		 (( (Vmax * A) ) / (Km_A + A)) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + Aflatoxin_B1 + H+ + NADPH -> NADP+ + Aflatoxin_M1 + H2O		 (( (Vmax * A) ) / (Km_A + A)) buffer: 80 mM potassium phosphate, 3.2 mg/ml butylated hydroxyl anisole-induced mouse cytosol, 5 mM glutathione, 5 mM MgCl2, 25 mM KCl, 0.25 mM sucrose
PH: 7.6
Temperature: 37
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

O2 + H+ + NADPH + Aflatoxin_B1 -> Aflatoxin_Q1 + H2O + NADP+		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

H+ + NADPH + Aflatoxin_B1 + O2 -> NADP+ + H2O + Aflatoxin_Q1		 (( (Vmax * (A ^ n)) ) / (K_A + (A ^ n))) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

NADPH + H+ + O2 + Aflatoxin_B1 -> NADP+ + H2O + Aflatoxin_B1_8,9_epoxide		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

H+ + O2 + Aflatoxin_B1 + NADPH -> NADP+ + H2O + Aflatoxin_B1_8,9_epoxide		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

H+ + NADPH + O2 + Aflatoxin_B1 -> H2O + NADP+ + Aflatoxin_B1_8,9_epoxide		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

H+ + O2 + NADPH + Aflatoxin_B1 -> H2O + NADP+ + Aflatoxin_M1		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

O2 + Aflatoxin_B1 + NADPH + H+ -> Aflatoxin_M1 + H2O + NADP+		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

O2 + H+ + Aflatoxin_B1 + NADPH -> Aflatoxin_M1 + NADP+ + H2O		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

Aflatoxin_B1 + H+ + O2 + NADPH -> H2O + NADP+ + Aflatoxin_M1		 (( (Vmax * A) ) / (Km_A + A)) buffer: PS-TNM, 3-4 mg/ml rat/butylated hydroxyanisole.treated mouse cytosolic protein, 1.0 mM NADP+, 0.5 U/ml glucose-6-phosphate dehydrogenase, 5 mM glucose-6-phosphate, 5 mM GSH
PH: 7.6
Temperature: 36
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + 7_Benzyloxyquinoline + NADPH + H+ -> H2O + NADP+ + Benzaldehyde + 7_Hydroxyquinoline		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + H+ + O2 + 7_Benzyloxyquinoline -> Benzaldehyde + H2O + NADP+ + 7_Hydroxyquinoline		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + 7_Benzyloxy_4_trifluoromethylcoumarin + NADPH -> NADP+ + 4_(Trifluoromethyl)umbelliferone + Benzaldehyde		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + 7_Benzyloxy_4_trifluoromethylcoumarin + NADPH + H+ -> 4_(Trifluoromethyl)umbelliferone + NADP+ + Benzaldehyde		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

NADPH + 7_Benzyloxyresorufin + H+ + O2 -> Resorufin + NADP+ + Benzaldehyde		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + NADPH + H+ + 7_Benzyloxyresorufin -> NADP+ + Benzaldehyde + Resorufin		 (( (Vmax * Km) ) / (S + Km)) buffer: 0.5 M potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype]

O2 + Fimasartan + NADPH -> H2O + NADP+ + 4_Hydroxybutyl_fimasartan		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Fimasartan + O2 -> H2O + NADP+ + Hydroxybutyl_fimasartan		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype]

Fimasartan + NADPH + O2 -> H2O + NADP+ + Fimasartan_S_oxide		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Fimasartan + O2 -> NADP+ + 1_Hydroxybutyl_fimasartan + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P20815 [unspecific monooxygenase(Enzyme) wildtype]

O2 + NADPH + Fimasartan -> H2O + NADP+ + Fimasartan_S_oxide		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype]

O2 + NADPH + Fimasartan -> NADP+ + Fimasartan_S_oxide + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype]

Fimasartan + NADPH + O2 -> H2O + NADP+ + BR_A_557		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Fimasartan + O2 -> H2O + BR_A_535 + NADP+		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P20815 [unspecific monooxygenase(Enzyme) wildtype]

O2 + Fimasartan + NADPH -> NADP+ + BR_A_557 + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, NADPH-regenerating system
PH: 7.4
Temperature: 37
uniprot:P10632 [unspecific monooxygenase(Enzyme) wildtype 2C8]

O2 + 4_Methyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide + NADPH -> NADP+ + H2O + 4_Hydroxymethyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris, 1 mM EDTA, 8 % glycerol (v/v), 1 mM NADP+, 10 mM Glucose 6-phosphate, 2 U/ml Glucose 6-phosphate dehydrogenase, human P450 reductase
PH: 7.4
Temperature: 28
uniprot:P33260 [unspecific monooxygenase(Enzyme) wildtype 2C18]

4_Methyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide + NADPH + O2 -> NADP+ + H2O + 4_Hydroxymethyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris, 1 mM EDTA, 8 % glycerol (v/v), 1 mM NADP+, 10 mM Glucose 6-phosphate, 2 U/ml Glucose 6-phosphate dehydrogenase, human P450 reductase
PH: 7.4
Temperature: 28
uniprot:P00179 [unspecific monooxygenase(Enzyme) wildtype 2C5dH]

O2 + NADPH + 4_Methyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide -> 4_Hydroxymethyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris, 1 mM EDTA, 8 % glycerol (v/v), 1 mM NADP+, 10 mM Glucose 6-phosphate, 2 U/ml Glucose 6-phosphate dehydrogenase, human P450 reductase
PH: 7.4
Temperature: 28
uniprot:P00179 [unspecific monooxygenase(Enzyme) wildtype 2C5/3LVdH]

4_Methyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide + NADPH + O2 -> NADP+ + H2O + 4_Hydroxymethyl_N_methyl_N_(2_phenyl_2H_pyrazol_3_yl)_benzene_sulfonamide		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris, 1 mM EDTA, 8 % glycerol (v/v), 1 mM NADP+, 10 mM Glucose 6-phosphate, 2 U/ml Glucose 6-phosphate dehydrogenase, human P450 reductase
PH: 7.4
Temperature: 28
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype CYP19]

Methadone -> Methanol + 2_Ethylidene_1,5_dimethyl_3,3_diphenylpyrrolidine		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate, 0,4 mM NADP, 4 mM glucose-6-phosphate, 1U/ml glucose-6-phosphate dehydrogenase, 2 mM MgCl2
PH: 7.4
Temperature: 37
uniprot:P11511 [unspecific monooxygenase(Enzyme) wildtype CYP19]

Methadone -> Methanol + 2_Ethylidene_1,5_dimethyl_3,3_diphenylpyrrolidine		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate, 0,4 mM NADP, 4 mM glucose-6-phosphate, 1U/ml glucose-6-phosphate dehydrogenase, 2 mM MgCl2
PH: 7.4
Temperature: 37
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6V]

NADPH + H+ + O2 + Coumarin -> NADP+ + H2O + Umbelliferone		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6A]

H+ + NADPH + Coumarin + O2 -> H2O + NADP+ + Umbelliferone		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) wildtype C6F]

NADPH + O2 + Coumarin + H+ -> H2O + NADP+ + Umbelliferone		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6L]

H+ + NADPH + O2 + Coumarin -> NADP+ + Umbelliferone + H2O		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6K]

NADPH + Coumarin + O2 + H+ -> H2O + Umbelliferone + NADP+		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6N]

NADPH + Coumarin + H+ + O2 -> NADP+ + H2O + Umbelliferone		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6G]

Coumarin + O2 + NADPH + H+ -> NADP+ + Umbelliferone + H2O		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:P20852 [unspecific monooxygenase(Enzyme) mutant C6S]

H+ + NADPH + O2 + Coumarin -> H2O + NADP+ + Umbelliferone		 (( (V * B) ) / (Km + B)) buffer: 50 mM potassium phosphate, 5 mM MgCl2, 60 nM NADPH-cytochrome P450 reductase, 12.0 µM dilauroylphosphatidylcholine
PH: 7.4
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

Palmitate + O2 + H+ + NADPH -> H2O + NADP+ + Hydroxylated_hexadecanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

Myristic_acid + O2 + NADPH + H+ -> Hydroxylated_tetradecanoate + NADP+ + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

NADPH + O2 + H+ + Dodecanoate -> H2O + NADP+ + Hydroxylated_dodecanoate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

NADPH + O2 + H+ + 13_Methyl_tetradecanoic_acid -> Hydroxylated_13_methyl_tetradecanoic_acid + H2O + NADP+		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

O2 + NADPH + H+ + 12_Methyl_tetradecanoic_acid -> Hydroxylated_12_methyl_tetradecanoic_acid + H2O + NADP+		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

NADPH + H+ + O2 + Linoleate -> Hydroxylated_linoleate + NADP+ + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

Palmitoleic_acid + O2 + H+ + NADPH -> Hydroxylated_palmitoleic_acid + NADP+ + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

H+ + O2 + NADPH + Stearate -> Hydroxylated_stearic_acid + NADP+ + H2O		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:Q65GU6 [unspecific monooxygenase(Enzyme) wildtype CYP102A7]

NADPH + Cytochrome_c + H+ -> Reduced_cytochrome_c + NADP+		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate
PH: 7.5
Temperature: 36
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d2]

NADP+ + Bufuralol -> 1_Hydroxy_bufuralol + NADPH + H+		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P12938 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d3]

NADP+ + Bufuralol -> 1_Hydroxy_bufuralol + H+ + NADPH		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d2]

Bufuralol + NADP+ -> NADPH + 1_Hydroxy_bufuralol + H+		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P12938 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d3]

Bufuralol + NADP+ -> NADPH + H+ + 1_Hydroxy_bufuralol		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d2]

NADP+ + Bufuralol -> H+ + 1_Hydroxy_bufuralol + NADPH		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d2]

NADP+ + Bufuralol -> H+ + 1_Hydroxy_bufuralol + NADPH		 (( (Vmax * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P12938 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d3]

Bufuralol + NADP+ -> NADPH + 1_Hydroxy_bufuralol + H+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P13108 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d4]

NADP+ + Bufuralol -> NADPH + H+ + 1_Hydroxy_bufuralol		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P10633 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d1]

NADP+ + Bufuralol -> 1_Hydroxy_bufuralol + NADPH + H+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme Cyp2d2]

Bufuralol + NADP+ -> NADPH + 1_Hydroxy_bufuralol + H+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 3.3 mM Glucose 6-phosphate, 0.4 U/ml Glucose 6-phosphate dehydrogenase, 1.3 mM MgCl2, 0.1 M Potassium phosphate
PH: 7.4
Temperature: 37
uniprot:P00185 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein + O2 -> Methanol + 5_Hydroxy_N,N_diisopropyltryptamine + H2O + Oxidized_flavoprotein		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + 5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein -> Oxidized_flavoprotein + 5_Hydroxy_N,N_diisopropyltryptamine + H2O + Methanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine -> 5_Hydroxy_N,N_diisopropyltryptamine + Methanol + Oxidized_flavoprotein + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine + O2 -> Oxidized_flavoprotein + Methanol + 5_Hydroxy_N,N_diisopropyltryptamine + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine + O2 -> Oxidized_flavoprotein + Methanol + 5_Hydroxy_N,N_diisopropyltryptamine + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine + O2 -> Methanol + 5_Hydroxy_N,N_diisopropyltryptamine + H2O + Oxidized_flavoprotein		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P11509 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2A6]

O2 + (_)_Camphor + H+ + NADPH -> (_)_exo_5_Hydroxycamphor + H2O + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM potassium phosphate, 0.5 mM NADP+, 5 mM glucose 6-phosphate, 1.0 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11509 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2A6]

O2 + NADPH + H+ + (_)_Camphor -> (_)_exo_5_Hydroxycamphor + H2O + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM potassium phosphate, 0.5 mM NADP+, 5 mM glucose 6-phosphate, 1.0 U/ml glucose 6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P04798 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

O2 + 5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein -> Oxidized_flavoprotein + Methanol + H2O + 5_Hydroxy_N,N_diisopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P10633 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2D1]

5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein + O2 -> 5_Methoxy_N_isopropyltryptamine + Oxidized_flavoprotein + H2O + 2_Propanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P04799 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A2]

O2 + Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine -> H2O + Oxidized_flavoprotein + 2_Propanol + 5_Methoxy_N_isopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P05178 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C6]

5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein + O2 -> H2O + 5_Methoxy_N_isopropyltryptamine + 2_Propanol + Oxidized_flavoprotein		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P08683 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C11]

5_Methoxy_N,N_diisopropyltryptamine + O2 + Reduced_flavoprotein -> 5_Methoxy_N_isopropyltryptamine + Oxidized_flavoprotein + H2O + 2_Propanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P00185 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine + O2 -> 2_Propanol + Oxidized_flavoprotein + H2O + 5_Methoxy_N_isopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P10634 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2D2]

5_Methoxy_N,N_diisopropyltryptamine + O2 + Reduced_flavoprotein -> Oxidized_flavoprotein + H2O + 5_Hydroxy_N,N_diisopropyltryptamine + Methanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P10633 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2D1]

5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein + O2 -> Methanol + Oxidized_flavoprotein + H2O + 5_Hydroxy_N,N_diisopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P05178 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C6]

Reduced_flavoprotein + O2 + 5_Methoxy_N,N_diisopropyltryptamine -> Oxidized_flavoprotein + H2O + 5_Hydroxy_N,N_diisopropyltryptamine + Methanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P04798 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

O2 + Reduced_flavoprotein + Melatonin -> Oxidized_flavoprotein + 6_Hydroxymelatonin + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM PBS, 1 mM NADPH
PH: 7.4
Temperature: 37
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A2]

Reduced_flavoprotein + Melatonin + O2 -> H2O + 6_Hydroxymelatonin + Oxidized_flavoprotein		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM PBS, 1 mM NADPH
PH: 7.4
Temperature: 37
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1B1]

Melatonin + O2 + Reduced_flavoprotein -> 6_Hydroxymelatonin + Oxidized_flavoprotein + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM PBS, 1 mM NADPH
PH: 7.4
Temperature: 37
uniprot:P11509 [unspecific monooxygenase(Enzyme) mutant isoenzyme CYP2A6 Ile471Thr]

H+ + O2 + NADPH + Coumarin -> H2O + Umbelliferone + NADP+		 (( (kcat_Km * E) ) * S) buffer: 50 mM potassium phosphate, 60 µg/ml dilauroylphosphatidylcholine, 0.28 U/ml NADPH-P450 reductase
PH: 7.25
Temperature: 37
uniprot:P20813 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2B6]

H+ + 7_Ethoxy_4_trifluoromethylcoumarin + O2 + NADPH -> NADP+ + Ethanol + 4_(Trifluoromethyl)umbelliferone		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 15 mM MgCl2, 0.1 mM EDTA, 0.3 U/ml NADPH-P450 reductase
PH: 7.6
Temperature: 37
uniprot:P20813 [unspecific monooxygenase(Enzyme) mutant isoenzyme CYP2B6 Pro167Ala]

O2 + NADPH + 7_Ethoxy_4_trifluoromethylcoumarin + H+ -> Ethanol + NADP+ + 4_(Trifluoromethyl)umbelliferone		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 15 mM MgCl2, 0.1 mM EDTA, 0.3 U/ml NADPH-P450 reductase
PH: 7.6
Temperature: 37
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A2]

7_Ethoxyresorufin + O2 + NADPH + H+ -> NADP+ + Ethanol + Resorufin		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 40 µg/ml dilauroylphosphatidylcholine, 0.21 U/ml NADPH-P450 reductase, 10 µM dicumarol
PH: 7.4
Temperature: 37
uniprot:P05177 [unspecific monooxygenase(Enzyme) mutant isoenzyme CYP1A2 Gln478His]

H+ + NADPH + 7_Ethoxyresorufin + O2 -> Ethanol + NADP+ + Resorufin		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, 40 µg/ml dilauroylphosphatidylcholine, 0.21 U/ml NADPH-P450 reductase, 10 µM dicumarol
PH: 7.4
Temperature: 37
uniprot:P20813 [unspecific monooxygenase(Enzyme) mutant isoenzyme CYP2B6 Arg487Cys]

H+ + NADPH + O2 + 7_Ethoxy_4_trifluoromethylcoumarin -> Ethanol + NADP+ + 4_(Trifluoromethyl)umbelliferone		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 15 mM MgCl2, 0.1 mM EDTA, 0.3 U/ml NADPH-P450 reductase
PH: 7.6
Temperature: 37
uniprot:P20813 [unspecific monooxygenase(Enzyme) mutant isoenzyme CYP2B6 Gln172His]

NADPH + H+ + O2 + 7_Ethoxy_4_trifluoromethylcoumarin -> NADP+ + Ethanol + 4_(Trifluoromethyl)umbelliferone		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM HEPES, 15 mM MgCl2, 0.1 mM EDTA, 0.3 U/ml NADPH-P450 reductase
PH: 7.6
Temperature: 37
uniprot:P04798 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

Reduced_flavoprotein + O2 + 5_Methoxy_N,N_diisopropyltryptamine -> 6_Hydroxy_5_methoxy_N,N_diisopropyltryptamine + Oxidized_flavoprotein + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P04798 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

O2 + Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine -> H2O + 5_Methoxy_N_isopropyltryptamine + 2_Propanol + Oxidized_flavoprotein		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P00185 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP1A1]

Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine + O2 -> Oxidized_flavoprotein + H2O + 6_Hydroxy_5_methoxy_N,N_diisopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P05183 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP3A2]

5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein + O2 -> 5_Methoxy_N_isopropyltryptamine + Oxidized_flavoprotein + H2O + 2_Propanol		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Reduced_flavoprotein + O2 + 5_Methoxy_N,N_diisopropyltryptamine -> H2O + Oxidized_flavoprotein + 6_Hydroxy_5_methoxy_N,N_diisopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + 5_Methoxy_N,N_diisopropyltryptamine + Reduced_flavoprotein -> 5_Methoxy_N_isopropyltryptamine + Oxidized_flavoprotein + 2_Propanol + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + Reduced_flavoprotein + 5_Methoxy_N,N_diisopropyltryptamine -> H2O + 2_Propanol + Oxidized_flavoprotein + 5_Methoxy_N_isopropyltryptamine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

Reduced_flavoprotein + O2 + 5_Methoxy_N,N_diisopropyltryptamine -> 5_Methoxy_N_isopropyltryptamine + 2_Propanol + Oxidized_flavoprotein + H2O		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

5_Methoxy_N,N_diisopropyltryptamine + O2 + Reduced_flavoprotein -> 5_Hydroxy_N,N_diisopropyltryptamine + Methanol + H2O + Oxidized_flavoprotein		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM potassium phosphate, 1 mM NADPH, 10 mM MgCl2, 0.2 mM EDTA, 10 mM Glucose 6-phosphate
PH: 7.4
Temperature: 37
uniprot:P05177 [unspecific monooxygenase(Enzyme) wildtype CYP1A2]

1_(3_Trifluoromethylphenyl)piperazine + O2 + Reduced_flavoprotein -> Hydroxy_TFMPP + H2O + Oxidized_flavoprotein		 (( (Vmax * S) ) / (Km + S)) buffer: 90 mM Phosphate, 5 mM Mg2+, 5 mM Isocitrate, 1.2 m NADP+, 2 U/ml Isocitrate dehydrogenase, 200 U/ml Superoxide dismutase
PH: 7.4
Temperature: 37
uniprot:P08684 [unspecific monooxygenase(Enzyme) wildtype CYP3A4]

O2 + Reduced_flavoprotein + 1_(3_Trifluoromethylphenyl)piperazine -> Hydroxy_TFMPP + Oxidized_flavoprotein + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 90 mM Phosphate, 5 mM Mg2+, 5 mM Isocitrate, 1.2 m NADP+, 2 U/ml Isocitrate dehydrogenase, 200 U/ml Superoxide dismutase
PH: 7.4
Temperature: 37
uniprot:P10635 [unspecific monooxygenase(Enzyme) wildtype CYP2D6]

Reduced_flavoprotein + O2 + 1_(3_Trifluoromethylphenyl)piperazine -> Hydroxy_TFMPP + Oxidized_flavoprotein + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 90 mM Phosphate, 5 mM Mg2+, 5 mM Isocitrate, 1.2 m NADP+, 2 U/ml Isocitrate dehydrogenase, 200 U/ml Superoxide dismutase
PH: 7.4
Temperature: 37
- [unspecific monooxygenase(Enzyme) wildtype]

O2 + 1_(3_Trifluoromethylphenyl)piperazine + Reduced_flavoprotein -> Oxidized_flavoprotein + Hydroxy_TFMPP + H2O		 (( (( (Vmax_1 * S) ) / (Km_1 + S)) ) + (( (Vmax_2 * S) ) / (Km_2 + S))) buffer: 90 mM Phosphate, 5 mM Mg2+, 5 mM Isocitrate, 1.2 m NADP+, 2 U/ml Isocitrate dehydrogenase, 200 U/ml Superoxide dismutase
PH: 7.4
Temperature: 37
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Dodecanoate + H+ + O2 -> Hydroxylated_dodecanoate + NADP+ + H2O		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

O2 + NADPH + H+ + Linoleate -> NADP+ + H2O + Hydroxylated_linoleate		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

O2 + H+ + Palmitate + NADPH -> Hydroxylated_palmitic_acid + H2O + NADP+		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

13_Methyl_tetradecanoic_acid + H+ + O2 + NADPH -> NADP+ + Hydroxylated_13_methyl_tetradecanoic_acid + H2O		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

O2 + 12_Methyl_tetradecanoic_acid + H+ + NADPH -> NADP+ + Hydroxylated_12_methyl_tetradecanoic_acid + H2O		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

O2 + H+ + 14_Methyl_pentadecanoic_acid + NADPH -> H2O + Hydroxylated_14_methyl_pentadecanoic_acid + NADP+		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + Myristic_acid + NADPH -> Hydroxylated_tetradecanoate + H2O + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

Stearate + O2 + H+ + NADPH -> H2O + Hydroxylated_stearic_acid + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + Phytanate + H+ -> NADP+ + H2O + Hydroxylated_phytanate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

O2 + NADPH + 15_Methyl_palmitic_acid + H+ -> H2O + Hydroxylated_15_methyl_palmitic_acid + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + Arachidonate + H+ -> H2O + Hydroxylated_arachidonic_acid + NADP+		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + H+ + Myristic_acid -> NADP+ + Hydroxylated_tetradecanoate + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

H+ + Palmitate + NADPH + O2 -> NADP+ + H2O + Hydroxylated_palmitic_acid		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + H+ + Dodecanoate -> NADP+ + Hydroxylated_dodecanoate + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + O2 + Stearate + H+ -> NADP+ + Hydroxylated_stearic_acid + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

NADH + Cytochrome_c + H+ -> NAD+ + Reduced_cytochrome_c		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

H+ + 2 Hexacyanoferrate(III) + NADPH -> 2 Hexacyanoferrate(II) + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + Cytochrome_c + H+ -> Reduced_cytochrome_c + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08394 [unspecific monooxygenase(Enzyme) wildtype]

H+ + Cytochrome_c + NADPH -> Reduced_cytochrome_c + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

Linoleate + NADPH + O2 + H+ -> H2O + Hydroxylated_linoleate + NADP+		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

H+ + O2 + NADPH + 13_Methyl_tetradecanoic_acid -> H2O + Hydroxylated_13_methyl_tetradecanoic_acid + NADP+		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

12_Methyl_tetradecanoic_acid + H+ + O2 + NADPH -> H2O + NADP+ + Hydroxylated_12_methyl_tetradecanoic_acid		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

14_Methyl_pentadecanoic_acid + NADPH + H+ + O2 -> Hydroxylated_14_methyl_pentadecanoic_acid + NADP+ + H2O		 (( (( (E * kcat) ) * (S ^ h)) ) / (( (S_half ^ h) ) + (S ^ h))) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

H+ + NADPH + O2 + Arachidonate -> H2O + NADP+ + Hydroxylated_arachidonic_acid		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + H+ + Phytanate + O2 -> NADP+ + Hydroxylated_phytanate + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

NADPH + H+ + O2 + 15_Methyl_palmitic_acid -> Hydroxylated_15_methyl_palmitic_acid + H2O + NADP+		 (( (E * kcat) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

2 Hexacyanoferrate(III) + H+ + NADPH -> NADP+ + 2 Hexacyanoferrate(II)		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

H+ + Cytochrome_c + NADPH -> Reduced_cytochrome_c + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

H+ + NADH + Cytochrome_c -> Reduced_cytochrome_c + NAD+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:O08336 [unspecific monooxygenase(Enzyme) wildtype]

Cytochrome_c + NADPH + H+ -> Reduced_cytochrome_c + NADP+		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 20 mM 3-(N-morpholino)propanesulfonic acid, 100 mM KCl
PH: 7.4
Temperature: 30
uniprot:P05183 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP3A2]

O2 + H+ + Deltamethrin + NADPH -> NADP+ + Hydroxydeltamethrin + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P08683 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C11]

H+ + NADPH + O2 + Deltamethrin -> Hydroxydeltamethrin + NADP+ + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P05178 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C6]

Deltamethrin + NADPH + O2 + H+ -> Hydroxydeltamethrin + NADP+ + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P10632 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C8]

Deltamethrin + NADPH + O2 + H+ -> Hydroxydeltamethrin + H2O + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P33261 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C19]

O2 + H+ + Deltamethrin + NADPH -> NADP+ + H2O + Hydroxydeltamethrin		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C9]

NADPH + O2 + Esfenvalerate + H+ -> H2O + NADP+ + Hydroxyesfenvalerate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P10632 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C8]

NADPH + Esfenvalerate + O2 + H+ -> H2O + Hydroxyesfenvalerate + NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P33261 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C19]

NADPH + Esfenvalerate + H+ + O2 -> Hydroxyesfenvalerate + NADP+ + H2O		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P05183 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP3A2]

H+ + Esfenvalerate + NADPH + O2 -> NADP+ + H2O + Hydroxyesfenvalerate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P08683 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C11]

NADPH + Esfenvalerate + H+ + O2 -> H2O + NADP+ + Hydroxyesfenvalerate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P05178 [unspecific monooxygenase(Enzyme) wildtype isoenzyme CYP2C6]

O2 + H+ + Esfenvalerate + NADPH -> NADP+ + H2O + Hydroxyesfenvalerate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P11712 [Heme]

O2 + H+ + Tolbutamide + NADPH -> H2O + Hydroxytolbutamide + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

O2 + H+ + Tolbutamide + NADPH -> H2O + NADP+ + Hydroxytolbutamide		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

H+ + Tolbutamide + O2 + NADPH -> H2O + NADP+ + Hydroxytolbutamide		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

NADPH + O2 + Diclofenac + H+ -> H2O + NADP+ + 4'_Hydroxydiclofenac		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

Diclofenac + H+ + O2 + NADPH -> H2O + NADP+ + 4'_Hydroxydiclofenac		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

NADPH + H+ + Diclofenac + O2 -> NADP+ + 4'_Hydroxydiclofenac + H2O		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

NADPH + H+ + O2 + Losartan -> H2O + NADP+ + Losartan_carboxylic_acid		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

O2 + Losartan + H+ + NADPH -> H2O + NADP+ + Losartan_carboxylic_acid		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [Heme]

H+ + Losartan + NADPH + O2 -> H2O + Losartan_carboxylic_acid + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, NADPH regenerating system
PH: 7.5
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*2]

[reduced_NADPH_hemoprotein_reductase] + Glimepiride + O2 -> H2O + [oxidized_NADPH_hemoprotein_reductase] + Hydroxyglimepiride		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*3]

[reduced_NADPH_hemoprotein_reductase] + O2 + Glimepiride -> H2O + Hydroxyglimepiride + [oxidized_NADPH_hemoprotein_reductase]		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*1]

[reduced_NADPH_hemoprotein_reductase] + Glimepiride + O2 -> H2O + Hydroxyglimepiride + [oxidized_NADPH_hemoprotein_reductase]		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*1]

O2 + Gliclazide + [reduced_NADPH_hemoprotein_reductase] -> H2O + Methylhydroxygliclazide + [oxidized_NADPH_hemoprotein_reductase]		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P00178 [Cytochrome b5]

NADPH + O2 + 7_Ethoxycoumarin + H+ -> NADP+ + Acetaldehyde + Umbelliferone + H2O		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 25 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P00178 [Cytochrome b5]

O2 + H+ + NADPH + 7_Ethoxycoumarin -> Umbelliferone + H2O + Acetaldehyde + NADP+		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 25 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P00178 [Cytochrome b5]

O2 + NADPH + H+ + 7_Ethoxycoumarin -> Acetaldehyde + H2O + NADP+ + Umbelliferone		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 25 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P00178 [Cytochrome b5]

O2 + 7_Ethoxycoumarin + NADPH + H+ -> NADP+ + Acetaldehyde + H2O + Umbelliferone		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 25 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P00178 [NADPH-cytochrome P450 reductase]

H+ + O2 + NADPH + 7_Ethoxycoumarin -> H2O + NADP+ + Umbelliferone + Acetaldehyde		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 25 mM Tris-HCl
PH: 7.5
Temperature: 30
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*2]

O2 + [reduced_NADPH_hemoprotein_reductase] + Gliclazide -> Methylhydroxygliclazide + H2O + [oxidized_NADPH_hemoprotein_reductase]		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11712 [unspecific monooxygenase(Enzyme) wildtype CYP2C9*3]

[reduced_NADPH_hemoprotein_reductase] + O2 + Gliclazide -> H2O + [oxidized_NADPH_hemoprotein_reductase] + Methylhydroxygliclazide		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM sodium phosphate, 1.3 mM NADP+, 3.3 mM Glucose-6-phosphate, 3.3 mM MgCl2, 0.4 U/ml Glucose-6-phosphate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:P11509 [unspecific monooxygenase(Enzyme) mutant CYP2A6dH (lacking N-terminal transmembrane signal anchor domain)]

NADPH + O2 + Coumarin + H+ -> Umbelliferone + NADP+ + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Tris, 50 mM isocitrate, 50 mM MgCl2, 5 U/ml isocitrate dehydrogenase
PH: 7.4
Temperature: 37
uniprot:Q81BF4 [unspecific monooxygenase(Enzyme) wildtype]

Linoleate + H+ + O2 + NADPH -> NADP+ + Hydroxylated_linoleate + H2O		 (( (( (E * kcat) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM potassium phosphate, 100 mM KCl
PH: 7.4
Temperature: 22
uniprot:Q81BF4 [unspecific monooxygenase(Enzyme) wildtype]

Palmitate + NADPH + O2 + H+ -> Hydroxylated_hexadecanoate + NADP+ + H2O		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 100 mM KCl
PH: 7.4
Temperature: 22
uniprot:Q16678 [unspecific monooxygenase(Enzyme) wildtype]

H+ + Estradiol_17beta + O2 + NADPH -> 4_Hydroxyestradiol_17beta + H2O + NADP+		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-HCl, 0.5 mM ascorbic acid, 5 mM MgCl2, 50 µM EDTA, 1 U/ml Glucose-6-phosphate dehydrogenase, 5 mM Glucose-6-phosphate
PH: 7.4
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-5453 methylglyoxal degradation III
BioCyc:HUMAN_PWY66-161 oxidative ethanol degradation III
BioCyc:HUMAN_PWY66-401 superpathway of tryptophan utilization
BioCyc:HUMAN_PWY-6402 superpathway of melatonin degradation
BioCyc:META_PWY66-161 ethanol degradation III
BioCyc:META_PWY-6377 α-tocopherol degradation
BioCyc:MOUSE_PWY66-241 bupropion degradation
BioCyc:MOUSE_PWY66-221 nicotine degradation III
BioCyc:MOUSE_PWY66-201 nicotine degradation II
BioCyc:HUMAN_PWY-5451 acetone degradation I (to methylglyoxal)
BioCyc:HUMAN_PWY-6377 α-tocopherol degradation
BioCyc:HUMAN_PWY-6398 melatonin degradation I
BioCyc:META_PWY-6733 sporopollenin precursors biosynthesis
BioCyc:META_PWY-7926 carbon disulfide oxidation III (metazoa)
BioCyc:META_PWY-7466 acetone degradation III (to propane-1,2-diol)
BioCyc:META_PWY-321 cutin biosynthesis
BioCyc:META_PWY-6398 melatonin degradation I
BioCyc:META_PWY-5270 morphine biosynthesis
BioCyc:META_PWY-5451 acetone degradation I (to methylglyoxal)
BioCyc:META_PWY-6402 superpathway of melatonin degradation
Reactome:R-MMU-9753281 APAP ADME
Reactome:R-RNO-9748784 Drug ADME
Reactome:R-HSA-9754706 Atorvastatin ADME
Reactome:R-CFA-9748784 Drug ADME
Reactome:R-RNO-9753281 APAP ADME
Reactome:R-HSA-9757110 Prednisone ADME
Reactome:R-HSA-9753281 APAP ADME
Reactome:R-MMU-9748784 Drug ADME
Reactome:R-CFA-9753281 APAP ADME
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-CFA-1430728 Metabolism
Reactome:R-CFA-556833 Metabolism of lipids
Reactome:R-HSA-400206 Regulation of lipid metabolism by PPARalpha
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-156581 Methylation
Reactome:R-HSA-5423646 Aflatoxin activation and detoxification
Reactome:R-HSA-5362517 Signaling by Retinoic Acid
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-9027307 Biosynthesis of maresin-like SPMs
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-156581 Methylation
Reactome:R-MMU-5423646 Aflatoxin activation and detoxification
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-RNO-9018677 Biosynthesis of DHA-derived SPMs
Reactome:R-RNO-9018682 Biosynthesis of maresins
Reactome:R-RNO-211945 Phase I - Functionalization of compounds
Reactome:R-RNO-211981 Xenobiotics
Reactome:R-CFA-9027307 Biosynthesis of maresin-like SPMs
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-9027307 Biosynthesis of maresin-like SPMs
Reactome:R-HSA-211976 Endogenous sterols
Reactome:R-HSA-211958 Miscellaneous substrates
Reactome:R-HSA-156580 Phase II - Conjugation of compounds
Reactome:R-HSA-9006931 Signaling by Nuclear Receptors
Reactome:R-MMU-9018677 Biosynthesis of DHA-derived SPMs
Reactome:R-MMU-9018682 Biosynthesis of maresins
Reactome:R-MMU-211976 Endogenous sterols
Reactome:R-MMU-156580 Phase II - Conjugation of compounds
Reactome:R-MMU-5365859 RA biosynthesis pathway
Reactome:R-RNO-9018678 Biosynthesis of specialized proresolving mediators (SPMs)
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-RNO-156581 Methylation
Reactome:R-RNO-5423646 Aflatoxin activation and detoxification
Reactome:R-CFA-9018678 Biosynthesis of specialized proresolving mediators (SPMs)
Reactome:R-HSA-1989781 PPARA activates gene expression
Reactome:R-HSA-9018678 Biosynthesis of specialized proresolving mediators (SPMs)
Reactome:R-HSA-211945 Phase I - Functionalization of compounds
Reactome:R-HSA-211981 Xenobiotics
Reactome:R-HSA-5365859 RA biosynthesis pathway
Reactome:R-MMU-211945 Phase I - Functionalization of compounds
Reactome:R-MMU-211981 Xenobiotics
Reactome:R-MMU-9006931 Signaling by Nuclear Receptors
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-9027307 Biosynthesis of maresin-like SPMs
Reactome:R-RNO-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-RNO-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Reactome:R-CFA-9018677 Biosynthesis of DHA-derived SPMs
Reactome:R-CFA-9018682 Biosynthesis of maresins
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-9018677 Biosynthesis of DHA-derived SPMs
Reactome:R-HSA-9018682 Biosynthesis of maresins
Reactome:R-HSA-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-HSA-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Reactome:R-HSA-211916 Vitamins
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-MMU-9018678 Biosynthesis of specialized proresolving mediators (SPMs)
Reactome:R-MMU-211897 Cytochrome P450 - arranged by substrate type
Reactome:R-MMU-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Reactome:R-MMU-211916 Vitamins
Reactome:R-MMU-5362517 Signaling by Retinoic Acid
Reactome:R-RNO-211976 Endogenous sterols
Reactome:R-RNO-156580 Phase II - Conjugation of compounds
WikiPathways:WP5188 Retinol metabolism
WikiPathways:WP5280 Glucocorticoid biosynthesis
WikiPathways:WP4545 Oxysterols derived from cholesterol
WikiPathways:WP2491 Diclofenac metabolic pathway
WikiPathways:WP2536 Colchicine metabolic pathway
WikiPathways:WP4174 Metabolism of tetrahydrocannabinol (THC)
PathBank:SMP0120730 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0120641 Corticosterone Methyl Oxidase I Deficiency (CMO I)
PathBank:SMP0120649 Apparent Mineralocorticoid Excess Syndrome
PathBank:SMP0000028 Caffeine Metabolism
PathBank:SMP0000083 Acetylsalicylic Acid Action Pathway
PathBank:SMP0000087 Rofecoxib Action Pathway
PathBank:SMP0000094 Sulindac Action Pathway
PathBank:SMP0000439 Vinorelbine Action Pathway
PathBank:SMP0000447 Cyclophosphamide Action Pathway
PathBank:SMP0000104 Indomethacin Action Pathway
PathBank:SMP0000120 Naproxen Action Pathway
PathBank:SMP0000106 Meloxicam Action Pathway
PathBank:SMP0000327 Phenytoin (Antiarrhythmic) Action Pathway
PathBank:SMP0000398 Lidocaine (Local Anaesthetic) Action Pathway
PathBank:SMP0000422 Imipramine Action Pathway
PathBank:SMP0000426 Fluoxetine Action Pathway
PathBank:SMP0000601 Etoposide Metabolism Pathway
PathBank:SMP0000605 Ifosfamide Metabolism Pathway
PathBank:SMP0000621 Codeine Metabolism Pathway
PathBank:SMP0000625 Imipramine Metabolism Pathway
PathBank:SMP0000633 Felbamate Metabolism Pathway
PathBank:SMP0000637 Tramadol Metabolism Pathway
PathBank:SMP0000641 Doxepin Metabolism Pathway
PathBank:SMP0000653 Rosiglitazone Metabolism Pathway
PathBank:SMP0000693 Antrafenine Action Pathway
PathBank:SMP0000697 Flurbiprofen Action Pathway
PathBank:SMP0000701 Phenylbutazone Action Pathway
PathBank:SMP0000705 Tiaprofenic Acid Action Pathway
PathBank:SMP0000709 Salicylic Acid Action Pathway
PathBank:SMP0087330 Tryptophan Metabolism
PathBank:SMP0063604 Caffeine Metabolism
PathBank:SMP0120451 Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency
PathBank:SMP0120640 21-Hydroxylase Deficiency (CYP21)
PathBank:SMP0000075 Arachidonic Acid Metabolism
PathBank:SMP0000086 Ibuprofen Action Pathway
PathBank:SMP0000093 Diclofenac Action Pathway
PathBank:SMP0000098 Ketorolac Action Pathway
PathBank:SMP0000102 Bromfenac Action Pathway
PathBank:SMP0000114 Nabumetone Action Pathway
PathBank:SMP0000405 Codeine Action Pathway
PathBank:SMP0000429 Disulfiram Action Pathway
PathBank:SMP0000600 Irinotecan Metabolism Pathway
PathBank:SMP0000604 Cyclophosphamide Metabolism Pathway
PathBank:SMP0000620 Lidocaine (Local Anaesthetic) Metabolism Pathway
PathBank:SMP0000624 Methadone Metabolism Pathway
PathBank:SMP0000636 Venlafaxine Metabolism Pathway
PathBank:SMP0000640 Acetaminophen Metabolism Pathway
PathBank:SMP0000644 Celecoxib Metabolism Pathway
PathBank:SMP0000648 Sorafenib Metabolism Pathway
PathBank:SMP0000652 Mycophenolic Acid Metabolism Pathway
PathBank:SMP0000692 Antipyrine Action Pathway
PathBank:SMP0000696 Fenoprofen Action Pathway
PathBank:SMP0000700 Lornoxicam Action Pathway
PathBank:SMP0000704 Tolmetin Action Pathway
PathBank:SMP0000708 Salicylate-Sodium Action Pathway
PathBank:SMP0087220 Arachidonic Acid Metabolism
PathBank:SMP0087293 Ethanol Degradation
PathBank:SMP0087353 Retinol Metabolism
PathBank:SMP0087365 Estrone Metabolism
PathBank:SMP0063595 Arachidonic Acid Metabolism
PathBank:SMP0063672 Steroidogenesis
PathBank:SMP0120720 Vitamin A Deficiency
PathBank:SMP0120630 17-alpha-Hydroxylase Deficiency (CYP17)
PathBank:SMP0120642 Corticosterone Methyl Oxidase II Deficiency (CMO II)
PathBank:SMP0120650 3-beta-Hydroxysteroid Dehydrogenase Deficiency
PathBank:SMP0000063 Tryptophan Metabolism
PathBank:SMP0000077 Piroxicam Action Pathway
PathBank:SMP0000084 Etodolac Action Pathway
PathBank:SMP0000074 Retinol Metabolism
PathBank:SMP0000336 Vitamin A Deficiency
PathBank:SMP0000436 Vinblastine Action Pathway
PathBank:SMP0000442 Etoposide Action Pathway
PathBank:SMP0000448 Ifosfamide Action Pathway
PathBank:SMP0000109 Mefenamic Acid Action Pathway
PathBank:SMP0000289 Diflunisal Action Pathway
PathBank:SMP0000116 Valdecoxib Action Pathway
PathBank:SMP0000263 Cilostazol Action Pathway
PathBank:SMP0000328 Lidocaine (Antiarrhythmic) Action Pathway
PathBank:SMP0000590 Ibuprofen Metabolism Pathway
PathBank:SMP0000602 Teniposide Metabolism Pathway
PathBank:SMP0000606 Tamoxifen Metabolism Pathway
PathBank:SMP0000610 Clopidogrel Metabolism Pathway
PathBank:SMP0000634 Carbamazepine Metabolism Pathway
PathBank:SMP0000638 Levomethadyl Acetate Metabolism Pathway
PathBank:SMP0000642 Nevirapine Metabolism Pathway
PathBank:SMP0000646 Fluoxetine Metabolism Pathway
PathBank:SMP0000694 Carprofen Action Pathway
PathBank:SMP0000698 Magnesium Salicylate Action Pathway
PathBank:SMP0000702 Nepafenac Action Pathway
PathBank:SMP0000706 Tenoxicam Action Pathway
PathBank:SMP0000710 Acetaminophen Action Pathway
PathBank:SMP0087236 Bile Acid Biosynthesis
PathBank:SMP0087260 Retinol Metabolism
PathBank:SMP0087272 Estrone Metabolism
PathBank:SMP0087288 Caffeine Metabolism
PathBank:SMP0063688 Androstenedione Metabolism
PathBank:SMP0030880 Estrone Metabolism
PathBank:SMP0120450 Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
PathBank:SMP0120470 Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH
PathBank:SMP0120510 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0120639 11-beta-Hydroxylase Deficiency (CYP11B1)
PathBank:SMP0000449 Ethanol Degradation
PathBank:SMP0000353 Leukotriene C4 Synthesis Deficiency
PathBank:SMP0000085 Ketoprofen Action Pathway
PathBank:SMP0000096 Celecoxib Action Pathway
PathBank:SMP0000433 Irinotecan Action Pathway
PathBank:SMP0000443 Teniposide Action Pathway
PathBank:SMP0000471 Tamoxifen Action Pathway
PathBank:SMP0000101 Suprofen Action Pathway
PathBank:SMP0000113 Oxaprozin Action Pathway
PathBank:SMP0000260 Clopidogrel Action Pathway
PathBank:SMP0000408 Methadone Action Pathway
PathBank:SMP0000424 Citalopram Action Pathway
PathBank:SMP0000440 Prednisone Action Pathway
PathBank:SMP0000627 Citalopram Metabolism Pathway
PathBank:SMP0000631 Prednisone Metabolism Pathway
PathBank:SMP0000635 Valproic Acid Metabolism Pathway
PathBank:SMP0000639 Clomipramine Metabolism Pathway
PathBank:SMP0000651 Artemether Metabolism Pathway
PathBank:SMP0000695 Etoricoxib Action Pathway
PathBank:SMP0000699 Lumiracoxib Action Pathway
PathBank:SMP0000703 Trisalicylate-Choline Action Pathway
PathBank:SMP0000707 Salsalate Action Pathway
PathBank:SMP0087315 Arachidonic Acid Metabolism