Lidocaine (Local Anaesthetic) Metabolism Pathway

Metabolites

2-Amino-3-methylbenzoate

Formula: C8H9NO2 (151.0633254)

CAS ID: 4389-45-1

2,6-Dimethylaniline

Formula: C8H11N (121.0891446)

CAS ID: 87-62-7

3-Hydroxylidocaine

Formula: C14H22N2O2 (250.1681192)

CAS ID: 34604-55-2

3-Hydroxymonoethylglycinexylidide

Formula: C12H18N2O2 (222.1368208)

CAS ID: 34604-56-3

4-Hydroxy-2,6-dimethylaniline

Formula: C8H11NO (137.0840596)

CAS ID: 3096-70-6

Formaldehyde

Formula: CH2O (30.0105642)

CAS ID: 50-00-0

Glycinexylidide

Formula: C10H14N2O (178.1106074)

CAS ID: 18865-38-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Lidocaine

Formula: C14H22N2O (234.1732042)

CAS ID: 137-58-6

Monoethylglycinexylidide

Formula: C12H18N2O (206.1419058)

CAS ID: 7728-40-7

NAD+

Formula: C21H28N7O14P2 (664.1169428000001)

CAS ID: 53-84-9

NADH

Formula: C21H29N7O14P2 (665.1247674)

CAS ID: 58-68-4

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7



Enzyme

EC Number name full name note
1.14.14.1 unspecific monooxygenase substrate,NADPH-hemoprotein reductase:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
1.14.14.55 quinine 3-monooxygenase quinine,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase
1.14.14.56 1,8-cineole 2-exo-monooxygenase 1,8-cineole,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating)
1.14.14.73 albendazole monooxygenase (sulfoxide-forming) albendazole,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (sulfoxide-forming)
4.2.1.152 hydroperoxy icosatetraenoate dehydratase hydroperoxyicosatetraenoate hydro-lyase (oxoicosatetraenoate-forming)


Proteins

Protein ID name full name