EC: 2.4.2.1

purine-nucleoside phosphorylase (purine-nucleoside:phosphate ribosyltransferase)

enzyme lambda metabolic reaction experiment
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + D_Ribose_1_phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 0.03 U/ml xanthine oxidase
PH: 7.4
Temperature: 36
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> D_Ribose_1_phosphate + Hypoxanthine		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 0.03 U/ml xanthine oxidase
PH: 7.4
Temperature: 36
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Hypoxanthine + D_Ribose_1_phosphate -> Phosphate + Inosine		 (( (Vmax * S) ) / (Km + S)) buffer: 25 mM MOPS
PH: 7.4
Temperature: 36
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 25 mM MOPS
PH: 7.4
Temperature: 36
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Deoxyinosine + Phosphate -> 2_Deoxy_D_ribose_1_phosphate + Hypoxanthine		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 0.03 U/ml xanthine oxidase
PH: 7.4
Temperature: 36
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 20 mM Tris-succinate, 16 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (Vmax * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 20 mM Tris-succinate, 16 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [Phosphate]

Inosine + Adenine -> Adenosine + Hypoxanthine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium arsenate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Adenine + 2_Deoxy_D_ribose_1_phosphate -> Phosphate + Deoxyadenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Adenine + 2_Deoxy_D_ribose_1_phosphate -> Deoxyadenosine + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Deoxyinosine + Phosphate -> Hypoxanthine + 2_Deoxy_D_ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Arsenate + Deoxyguanosine -> Guanine + 2_Deoxy_D_ribose_1_arsenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium arsenate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Arsenate + Deoxyadenosine -> 2_Deoxy_D_ribose_1_arsenate + Adenine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium arsenate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Deoxyinosine + Arsenate -> Hypoxanthine + 2_Deoxy_D_ribose_1_arsenate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM Potassium arsenate
PH: 7.1
Temperature: 37
uniprot:Q8ZJV7 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Arsenate + Inosine -> alpha_D_Ribose_1_arsenate + Hypoxanthine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium arsenate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

2_Deoxy_D_ribose_1_phosphate + Adenine -> Phosphate + Deoxyadenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Adenine + 2_Deoxy_D_ribose_1_phosphate -> Deoxyadenosine + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Deoxyinosine -> 2_Deoxy_D_ribose_1_phosphate + Hypoxanthine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [Phosphate]

Adenine + Inosine -> Hypoxanthine + Adenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

D_Ribose_1_phosphate + Adenine -> Phosphate + Adenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

D_Ribose_1_phosphate + Adenine -> Phosphate + Adenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM Tris-succinate
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Arsenate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_arsenate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.18 M Potassium phosphate, 16-24 mU/ml Xanthine oxidase
PH: 7.1
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Adenine + alpha_D_Ribose_1_phosphate -> Phosphate + Adenosine		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM HEPES
PH: 7.3
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Adenine + alpha_D_Ribose_1_phosphate -> Phosphate + Adenosine		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM HEPES
PH: 7.3
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Adenosine -> Adenine + alpha_D_Ribose_1_phosphate		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM HEPES
PH: 7.3
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Adenosine -> Adenine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM HEPES
PH: 7.3
Temperature: 37
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM HEPES
PH: 7.3
Temperature: 37
uniprot:Q8U4Q8 [purine-nucleoside phosphorylase(Enzyme) wildtype MTAP1]

Guanosine + Phosphate -> Guanine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 7.4
Temperature: 80
uniprot:Q8U4Q8 [purine-nucleoside phosphorylase(Enzyme) wildtype MTAP1]

Adenosine + Phosphate -> alpha_D_Ribose_1_phosphate + Adenine		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM potassium phosphate
PH: 7.4
Temperature: 80
- [Hypoxanthine]

Phosphate + Guanosine -> Guanine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + A)) buffer: 0.2 M Phosphate
PH: 6.25
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Guanosine -> Guanine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (( (Km * (1 + (P / Ki))) ) + A)) buffer: 0.2 M Phosphate
PH: 6.25
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Guanine + alpha_D_Ribose_1_phosphate -> Guanosine + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.2 M Citrate
PH: 6.3
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

alpha_D_Ribose_1_phosphate + Guanine -> Guanosine + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.2 M Citrate
PH: 6.3
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 0.2 M Phosphate
PH: 6.3
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Deoxyguanosine -> 2_Deoxy_D_ribose_1_phosphate + Guanine		 (( (Vmax * A) ) / (Km + A)) buffer: 0.2 M Phosphate
PH: 6.3
Temperature: 40
- [p-Chloromercuribenzoate]

Phosphate + Guanosine -> alpha_D_Ribose_1_phosphate + Guanine		 (( (Vmax * A) ) / (( (Km * (1 + (I / Ki))) ) + (A * (1 + (I / Ki))))) buffer: 0.2 M Phosphate
PH: 6.25
Temperature: 40
- [purine-nucleoside phosphorylase(Enzyme) wildtype]

Guanosine + Phosphate -> Guanine + alpha_D_Ribose_1_phosphate		 (( (Vmax * A) ) / (( (Km * (1 + (P / Ki))) ) + (A * (1 + (P / Ki))))) buffer: 0.2 M Phosphate
PH: 6.25
Temperature: 40
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (Vmax * A) ) * B) ) / (( (( (( (KiA * KmA) ) + (KmA * B)) ) + (KmB * A)) ) + (A * B))) buffer: 50 mM Tris-acetate, 0.02 µM Xanthine oxidase
PH: 7.5
Temperature: 22
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Arsenate -> alpha_D_Ribose_1_arsenate + Hypoxanthine		 (( (( (Vmax * A) ) * B) ) / (( (( (( (KiA * KmA) ) + (KmA * B)) ) + (KmB * A)) ) + (A * B))) buffer: 50 mM Tris-acetate, 0.02 µM Xanthine oxidase
PH: 7.5
Temperature: 22
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Arsenate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_arsenate		 (( (( (Vmax * A) ) * B) ) / (( (( (( (KiA * KmA) ) + (KmA * B)) ) + (KmB * A)) ) + (A * B))) buffer: 50 mM Tris-acetate, 0.02 µM Xanthine oxidase
PH: 7.5
Temperature: 22
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (Vmax * A) ) * B) ) / (( (( (( (KiA * KmA) ) + (KmA * B)) ) + (KmB * A)) ) + (A * B))) buffer: 50 mM Tris-acetate, 0.02 µM Xanthine oxidase
PH: 7.5
Temperature: 22
uniprot:P00491 [Deoxyinosine]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (( (( (( (( (V1 * A) ) / K1) ) + (( (( (V2 * (A ^ 2)) ) / K1) ) * K2)) ) + (( (( (( (V3_V_3 * A) ) * B) ) / K1) ) * K_3)) ) + (( (V_1 * B) ) / K_1)) ) + (( (( (V_2 * (B ^ 2)) ) / K_1) ) * K_2)) ) / (( (( (1 + (( (A / K1) ) * (1 + (A / K2)))) ) + (( (( (A * B) ) / K1) ) * K_3)) ) + (( (B / K_1) ) * (1 + (B / K_2))))) buffer: 50 mM Potassium phosphate, 0.02 µM Xanthine oxidase
PH: 7.5
Temperature: 22
uniprot:G1SN21 [5,5'-Dithiobis(2-nitrobenzoic acid)]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 50 mM Sodium phosphate, 0.02 units/ml Xanthine oxidase
PH: 7.5
Temperature: 40
uniprot:G1SN21 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Sodium phosphate, 0.02 units/ml Xanthine oxidase
PH: 7.5
Temperature: 40
uniprot:G1SN21 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (kcat * E) ) * (S ^ n)) ) / (( (S_half ^ n) ) + (S ^ n))) buffer: 50 mM Sodium phosphate, 0.02 units/ml Xanthine oxidase
PH: 7.5
Temperature: 40
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant E201A]

Hypoxanthine + alpha_D_Ribose_1_phosphate -> Phosphate + Inosine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant N243A]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant K244A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F200A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant E201A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant T242A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant T242A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant S33A]

Hypoxanthine + alpha_D_Ribose_1_phosphate -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H86A]

Hypoxanthine + alpha_D_Ribose_1_phosphate -> Phosphate + Inosine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant R84A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant E89A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H86A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant R84A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant S33A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant R84A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant S33A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant E201A]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F200A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant N243A]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant K244A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant M219A]

Hypoxanthine + alpha_D_Ribose_1_phosphate -> Phosphate + Inosine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant Y88F]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Phosphate + Inosine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F159A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H257A]

Hypoxanthine + alpha_D_Ribose_1_phosphate -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant Y88F]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F159A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant M219A]

Inosine + Phosphate -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant E89A]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H86A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F200A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant N243A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant K244A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Phosphate + Inosine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant T242A]

alpha_D_Ribose_1_phosphate + Hypoxanthine -> Inosine + Phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H257A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * B) ) / (Kb + B)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant H257A]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant Y88F]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant M219A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:P00491 [purine-nucleoside phosphorylase(Enzyme) mutant F159A]

Inosine + Phosphate -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * A) ) / (Ka + A)) buffer: 100 mM HEPES, 0.075% Triton X-100, 1 mM 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyltetrazolium chloride, 100 mU/ml xanthine oxidase
PH: 7
Temperature: 25
uniprot:Q8I3X4 [purine-nucleoside phosphorylase(Enzyme) mutant M183L]

Phosphate + Inosine -> alpha_D_Ribose_1_phosphate + Hypoxanthine		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 50 mU/ml xanthine oxidase
PH: 7.4
Temperature: 25
uniprot:Q8I3X4 [purine-nucleoside phosphorylase(Enzyme) mutant V181D]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 50 mU/ml xanthine oxidase
PH: 7.4
Temperature: 25
uniprot:Q8I3X4 [purine-nucleoside phosphorylase(Enzyme) wildtype]

Phosphate + Inosine -> Hypoxanthine + alpha_D_Ribose_1_phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM potassium phosphate, 50 mU/ml xanthine oxidase
PH: 7.4
Temperature: 25

Pathways

pathway id name
BioCyc:HUMAN_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:HUMAN_PWY-7179-1 purine deoxyribonucleosides degradation
BioCyc:META_PWY-7181 pyrimidine deoxyribonucleosides degradation
BioCyc:META_PWY-6753 S-methyl-5'-thioadenosine degradation III
BioCyc:META_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:META_PWY-7179 purine deoxyribonucleosides degradation I
BioCyc:META_PWY-5695 inosine 5'-phosphate degradation
BioCyc:META_PWY-6620 guanine and guanosine salvage
BioCyc:META_PWY66-409 superpathway of purine nucleotide salvage
BioCyc:META_PWY-6609 adenine and adenosine salvage III
BioCyc:ECO_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:ECO_PWY-7179 purine deoxyribonucleosides degradation I
BioCyc:ECO_PWY-7181 pyrimidine deoxyribonucleosides degradation
BioCyc:ECO_PWY0-181 salvage pathways of pyrimidine deoxyribonucleotides
BioCyc:VCHO_PWY-7179 purine deoxyribonucleosides degradation I
BioCyc:VCHO_PWY-6620 guanine and guanosine salvage
BioCyc:MTBH37RV_PWY-5695 inosine 5'-phosphate degradation
BioCyc:MTBCDC1551_PWY-6620 guanine and guanosine salvage
BioCyc:MTBCDC1551_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:HPY_PWY-6620 guanine and guanosine salvage
BioCyc:ECOO157_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:ECOO157_PWY0-1296 purine ribonucleosides degradation
BioCyc:ECOO157_PWY-7179 purine deoxyribonucleosides degradation
BioCyc:ECOO157_PWY-6579 superpathway of guanine and guanosine salvage
BioCyc:ECOO157_PWY-6609 adenine and adenosine salvage III
BioCyc:ECOO157_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:ANTHRA_PWY-6608 guanosine nucleotides degradation III
BioCyc:ANTHRA_PWY-6620 guanine and guanosine salvage
BioCyc:ANTHRA_PWY-7179 purine deoxyribonucleosides degradation I
BioCyc:ANTHRA_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:MOUSE_URSIN-PWY ureide biosynthesis
BioCyc:MOUSE_P121-PWY adenine and adenosine salvage I
BioCyc:MOUSE_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:MOUSE_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate
BioCyc:BSUB_PWY-6608 guanosine nucleotides degradation III
BioCyc:BSUB_URSIN-PWY ureide biosynthesis
BioCyc:BSUB_PWY0-1296 purine ribonucleosides degradation
BioCyc:ECOL316407_PWY-6611 adenine and adenosine salvage V
BioCyc:ECOL316407_PWY-6608 guanosine nucleotides degradation III
BioCyc:HUMAN_PWY66-409 superpathway of purine nucleotide salvage
BioCyc:META_PWY0-1296 purine ribonucleosides degradation
BioCyc:ECO_PWY-6579 superpathway of guanine and guanosine salvage
BioCyc:ECO_PWY0-1298 superpathway of pyrimidine deoxyribonucleosides degradation
BioCyc:VCHO_PWY0-1296 purine ribonucleosides degradation
BioCyc:VCHO_PWY-6611 adenine and adenosine salvage V
BioCyc:VCHO_PWY-6609 adenine and adenosine salvage III
BioCyc:MTBH37RV_PWY-6620 guanine and guanosine salvage
BioCyc:MTBH37RV_PWY0-1296 purine ribonucleosides degradation
BioCyc:MTBH37RV_PWY-7179 purine deoxyribonucleosides degradation I
BioCyc:MTBH37RV_PWY-6609 adenine and adenosine salvage III
BioCyc:MTBH37RV_P121-PWY adenine and adenosine salvage I
BioCyc:MTBH37RV_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:MTBCDC1551_PWY-6609 adenine and adenosine salvage III
BioCyc:ECOO157_PWY-6611 adenine and adenosine salvage V
BioCyc:ANTHRA_PWY0-1296 purine ribonucleosides degradation
BioCyc:MOUSE_P1-PWY purine and pyrimidine metabolism
BioCyc:MOUSE_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:MOUSE_PWY-6609 adenine and adenosine salvage III
BioCyc:BSUB_P1-PWY purine and pyrimidine metabolism
BioCyc:ECOL316407_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:HUMAN_PWY-6608 guanosine nucleotides degradation
BioCyc:HUMAN_SALVADEHYPOX-PWY adenosine nucleotides degradation
BioCyc:HUMAN_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate
BioCyc:HUMAN_PWY-6620 guanine and guanosine salvage
BioCyc:META_PWY-5532 nucleoside and nucleotide degradation (archaea)
BioCyc:META_PWY-6579 superpathway of guanine and guanosine salvage
BioCyc:META_PWY-6611 adenine and adenosine salvage V
BioCyc:META_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:META_PWY-6608 guanosine nucleotides degradation III
BioCyc:ECO_PWY-6609 adenine and adenosine salvage III
BioCyc:ECO_PWY0-1295 pyrimidine ribonucleosides degradation
BioCyc:ECO_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:YEAST_PWY3O-2220 salvage pathways of adenine, hypoxanthine and their nucleosides
BioCyc:YEAST_PWY3O-1 superpathway of purine nucleosides salvage
BioCyc:YEAST_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate
BioCyc:VCHO_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:VCHO_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:VCHO_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:VCHO_PWY-6579 superpathway of guanine and guanosine salvage
BioCyc:MTBCDC1551_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:MTBCDC1551_PWY-6627 salinosporamide A biosynthesis
BioCyc:MTBCDC1551_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:HPY_PWY0-1296 purine ribonucleosides degradation
BioCyc:HPY_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:ECOO157_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:ECOO157_PWY-6620 guanine and guanosine salvage I
BioCyc:MOUSE_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:ECOL316407_PWY-6609 adenine and adenosine salvage III
BioCyc:ECOL316407_PWY-6579 superpathway of guanine and guanosine salvage
BioCyc:ECOL316407_PWY0-1296 purine ribonucleosides degradation
BioCyc:HUMAN_PWY-6353 purine nucleotides degradation
BioCyc:HUMAN_PWY-6609 adenine and adenosine salvage III
BioCyc:META_PWY0-1295 pyrimidine ribonucleosides degradation
BioCyc:META_PWY0-1298 superpathway of pyrimidine deoxyribonucleosides degradation
BioCyc:META_PWY-7179-1 purine deoxyribonucleosides degradation II
BioCyc:META_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:META_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:ECO_PWY-6620 guanine and guanosine salvage
BioCyc:ECO_PWY-6611 adenine and adenosine salvage V
BioCyc:ECO_PWY0-1296 purine ribonucleosides degradation
BioCyc:ECO_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:ECO_PWY-6608 guanosine nucleotides degradation III
BioCyc:ECO_PWY0-163 salvage pathways of pyrimidine ribonucleotides
BioCyc:YEAST_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:VCHO_P121-PWY adenine and adenosine salvage I
BioCyc:PLASMO_PWY0-163 salvage pathways of pyrimidine ribonucleotides
BioCyc:PLASMO_DRIBOPMET-PWY (deoxy)ribose phosphate degradation
BioCyc:MTBH37RV_PWY0-1297 superpathway of purine deoxyribonucleosides degradation
BioCyc:MTBCDC1551_P121-PWY adenine and adenosine salvage I
BioCyc:MTBCDC1551_PWY0-1296 purine ribonucleosides degradation
BioCyc:MTBCDC1551_PWY-7179 purine deoxyribonucleosides degradation
BioCyc:HPY_PWY-6609 adenine and adenosine salvage III
BioCyc:ECOO157_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:ECOO157_PWY-6608 guanosine nucleotides degradation III
BioCyc:ECOO157_P121-PWY adenine and adenosine salvage I
BioCyc:ANTHRA_PWY-6609 adenine and adenosine salvage III
BioCyc:BSUB_SALVPURINE2-PWY xanthine and xanthosine salvage
BioCyc:BSUB_PWY-6620 guanine and guanosine salvage
BioCyc:BSUB_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:BSUB_PWY-5695 inosine 5'-phosphate degradation
BioCyc:ECOL316407_PWY-6620 guanine and guanosine salvage
BioCyc:ECOL316407_SALVADEHYPOX-PWY adenosine nucleotides degradation II
PathBank:SMP0002081 Adenine and Adenosine Salvage I
PathBank:SMP0002083 Adenine and Adenosine Salvage II
PathBank:SMP0002086 Guanine and Guanosine Salvage
PathBank:SMP0002088 Purine Ribonucleosides Degradation
PathBank:SMP0002089 Purine Deoxyribonucleosides Degradation
PathBank:SMP0002103 Adenosine Nucleotides Degradation
Reactome:R-RNO-9748784 Drug ADME
Reactome:R-SCE-9748784 Drug ADME
Reactome:R-HSA-9735763 Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine
Reactome:R-SPO-9755088 Ribavirin ADME
Reactome:R-SPO-9748784 Drug ADME
Reactome:R-HSA-9735786 Nucleotide catabolism defects
Reactome:R-RNO-9755088 Ribavirin ADME
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-HSA-9735804 Diseases of nucleotide metabolism
Reactome:R-HSA-9755088 Ribavirin ADME
Reactome:R-SCE-9755088 Ribavirin ADME
Reactome:R-HSA-74217 Purine salvage
Reactome:R-HSA-1643685 Disease
Reactome:R-RNO-74217 Purine salvage
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-15869 Nucleotide metabolism
Reactome:R-SPO-8956319 Nucleotide catabolism
Reactome:R-HSA-8956321 Nucleotide salvage
Reactome:R-HSA-74259 Purine catabolism
Reactome:R-RNO-8956321 Nucleotide salvage
Reactome:R-RNO-74259 Purine catabolism
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-74217 Purine salvage
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-SCE-15869 Nucleotide metabolism
Reactome:R-SCE-8956319 Nucleotide catabolism
Reactome:R-SPO-8956321 Nucleotide salvage
Reactome:R-SPO-74259 Purine catabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-HSA-8956319 Nucleotide catabolism
Reactome:R-RNO-15869 Nucleotide metabolism
Reactome:R-RNO-8956319 Nucleotide catabolism
Reactome:R-SCE-8956321 Nucleotide salvage
Reactome:R-SCE-74259 Purine catabolism
Reactome:R-SPO-74217 Purine salvage
WikiPathways:WP4792 Purine metabolism
WikiPathways:WP4224 Purine metabolism and related disorders
PathBank:SMP0000167 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0000512 Xanthinuria Type I
PathBank:SMP0000536 Mitochondrial DNA Depletion Syndrome-3
PathBank:SMP0000050 Purine Metabolism
PathBank:SMP0000144 Adenosine Deaminase Deficiency
PathBank:SMP0000203 Molybdenum Cofactor Deficiency
PathBank:SMP0000428 Mercaptopurine Action Pathway
PathBank:SMP0000535 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0000365 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0000210 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0000430 Thioguanine Action Pathway
PathBank:SMP0000513 Xanthinuria Type II
PathBank:SMP0000537 Myoadenylate Deaminase Deficiency
PathBank:SMP0121123 Arsenate Detoxification
PathBank:SMP0000048 Nicotinate and Nicotinamide Metabolism
PathBank:SMP0000364 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0000168 AICA-Ribosiduria
PathBank:SMP0000427 Azathioprine Action Pathway