Purine catabolism

Watts RW. Molecular variation in relation to purine metabolism. J Clin Pathol Suppl (R Coll Pathol). 1974;8():48–63. PMID: 4620886; PMCID: PMC1347204.

Metabolites

Adenosine

Formula: C10H13N5O4 (267.09674980000005)

CAS ID: 58-61-7

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Molybdopterin

Formula: C10H14N5O6PS2 (395.01231140000004)

CAS ID: 220399-50-8

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Urate

Formula: C5H4N4O3 (168.0283394)

CAS ID: 69-93-2

Xanthine

Formula: C5H4N4O2 (152.0334244)

CAS ID: 69-89-6

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

IDP(3-)

Formula: C10H11N4O11P2 (424.98995759999997)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

8-oxo-dGTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID:

2-hydroxy-dATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

2'-deoxyguanosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID: 7720-24-3



Enzyme

EC Number name full name note
3.1.3.-
1.17.1.4 xanthine dehydrogenase xanthine:NAD+ oxidoreductase
1.17.3.2 xanthine oxidase xanthine:oxygen oxidoreductase
2.4.2.1 purine-nucleoside phosphorylase purine-nucleoside:phosphate ribosyltransferase
2.7.1.77 nucleoside phosphotransferase nucleotide:nucleoside 5'-phosphotransferase
2.7.7.96 ADP-D-ribose pyrophosphorylase ATP:D-ribose 5-phosphate adenylyltransferase
3.1.3.35 thymidylate 5'-phosphatase thymidylate 5'-phosphohydrolase
3.1.3.5 5'-nucleotidase 5'-ribonucleotide phosphohydrolase
3.1.3.89 5'-deoxynucleotidase 2'-deoxyribonucleoside 5'-monophosphate phosphohydrolase
3.1.3.91 7-methylguanosine nucleotidase N7-methyl-GMP phosphohydrolase
3.1.3.99 IMP-specific 5'-nucleotidase inosine 5'-phosphate phosphohydrolase
3.5.4.3 guanine deaminase guanine aminohydrolase
3.6.1.13 ADP-ribose diphosphatase ADP-D-ribose ribophosphohydrolase
3.6.1.16 CDP-glycerol diphosphatase CDP-glycerol phosphoglycerohydrolase
3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase CDP-choline phosphohydrolase
3.6.1.58 8-oxo-dGDP phosphatase 8-oxo-dGDP phosphohydrolase
3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] N7-methylguanosine-5'-diphosphate phosphohydrolase
3.6.1.64 inosine diphosphate phosphatase inosine diphosphate phosphatase
3.6.1.66 XTP/dITP diphosphatase XTP/dITP diphosphohydrolase (diphosphate-forming)
3.6.1.68 geranyl diphosphate phosphohydrolase geranyl-diphosphate phosphohydrolase
3.6.1.76 prenyl-diphosphate phosphatase prenyl diphosphate/3-methylbut-3-en-1-yl diphosphate phosphohydrolase
3.6.1.9 nucleotide diphosphatase dinucleotide nucleotidohydrolase


Proteins

Protein ID name full name