adenine and adenosine salvage III
Bzowska A, Kulikowska E, Shugar D. Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacol Ther. 2000 Dec;88(3):349–425. doi: 10.1016/s0163-7258(00)00097-8. PMID: 11337031.; Elshafei AM, Abu-Shady MR, el-Beih FM, Mohamed LA. Mode and extent of degradation of adenosine and guanosine by extracts of Aspergillus terricola. Microbiol Res. 1995 Sep;150(3):291–5. doi: 10.1016/s0944-5013(11)80008-x. PMID: 7551735.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.4.2.- | |||
| 2.4.2.1 | purine-nucleoside phosphorylase | purine-nucleoside:phosphate ribosyltransferase | |
| 2.4.2.2 | pyrimidine-nucleoside phosphorylase | pyrimidine-nucleoside:phosphate (2'-deoxy)-alpha-D-ribosyltransferase | |
| 2.4.2.22 | xanthine phosphoribosyltransferase | XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase | |
| 2.4.2.8 | hypoxanthine phosphoribosyltransferase | IMP:diphosphate phospho-D-ribosyltransferase | |
| 3.5.4.4 | adenosine deaminase | adenosine aminohydrolase |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P0A9M2 | hpt | Hypoxanthine phosphoribosyltransferase |
| P0A9M5 | gpt | Xanthine-guanine phosphoribosyltransferase |
| P0ABP8 | deoD | Purine nucleoside phosphorylase DeoD-type |
| P0C037 | ppnP | Pyrimidine/purine nucleoside phosphorylase |
| P22333 | add | Adenosine deaminase |
| P45563 | xapA | Purine nucleoside phosphorylase 2 |