Nucleotide catabolism
Tamaki N, Sakata SF, Matsuda K. Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver. Methods Enzymol. 2000;324():376–89. doi: 10.1016/s0076-6879(00)24247-x. PMID: 10989446.; Griffith OW. Beta-amino acids: mammalian metabolism and utility as alpha-amino acid analogues. Annu Rev Biochem. 1986;55():855–78. doi: 10.1146/annurev.bi.55.070186.004231. PMID: 3090932.; Watts RW. Molecular variation in relation to purine metabolism. J Clin Pathol Suppl (R Coll Pathol). 1974;8():48–63. PMID: 4620886; PMCID: PMC1347204.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.4.2.1 | purine-nucleoside phosphorylase | purine-nucleoside:phosphate ribosyltransferase | |
| 3.5.4.3 | guanine deaminase | guanine aminohydrolase | |
| 3.6.1.13 | ADP-ribose diphosphatase | ADP-D-ribose ribophosphohydrolase | |
| 3.6.1.42 | guanosine-diphosphatase | GDP phosphohydrolase | |
| 3.6.1.5 | apyrase | nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming) | |
| 3.6.1.66 | XTP/dITP diphosphatase | XTP/dITP diphosphohydrolase (diphosphate-forming) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P32621 | GDA1 | Guanosine-diphosphatase |
| P40009 | YND1 | Golgi apyrase |
| P47119 | HAM1 | Inosine triphosphate pyrophosphatase |
| Q01976 | YSA1 | ADP-ribose pyrophosphatase |
| Q05788 | PNP1 | Purine nucleoside phosphorylase |
| Q07729 | GUD1 | Probable guanine deaminase |