EC: 3.1.3.64

phosphatidylinositol-3-phosphatase (1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase)

enzyme lambda metabolic reaction experiment
- [phosphatidylinositol-3-phosphatase(Enzyme) wildtype isoenzyme 2]

H2O + D_myo_Inositol_1,3_bisphosphate -> Phosphate + 1D_myo_Inositol_1_phosphate
(( (Vmax * S) ) / (Km + S)) buffer: 20 mM MES, 2.5 mM EDTA, 1 mM MgCl2, 0.3% Octyl glucoside, 0.2 mg/ml Cytochrome c
PH: 6.5
Temperature: 37
- [phosphatidylinositol-3-phosphatase(Enzyme) wildtype isoenzyme 1]

H2O + D_myo_Inositol_1,3_bisphosphate -> Phosphate + 1D_myo_Inositol_1_phosphate
(( (Vmax * S) ) / (Km + S)) buffer: 20 mM MES, 2.5 mM EDTA, 1 mM MgCl2, 0.3% Octyl glucoside, 0.2 mg/ml Cytochrome c
PH: 6.5
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:ARA_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:MTBH37RV_NAD-BIOSYNTHESIS-II NAD salvage pathway III (to nicotinamide riboside)
BioCyc:MTBH37RV_NADPHOS-DEPHOS-PWY NAD phosphorylation and dephosphorylation
BioCyc:MOUSE_PWY3DJ-219 PIP metabolism
BioCyc:BTHE_PWY-5668 cardiolipin biosynthesis I
BioCyc:META_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:META_PWY-6368 3-phosphoinositide degradation
BioCyc:MTBH37RV_PWY-6348 phosphate acquisition
BioCyc:BTHE_PWY-5269 cardiolipin biosynthesis II
BioCyc:HUMAN_PWY-6368 3-phosphoinositide degradation
BioCyc:YEAST_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:BTHE_PWY0-1545 cardiolipin biosynthesis III
BioCyc:HUMAN_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:YEAST_PWY3O-242 phosphatidylinositol phosphate biosynthesis
BioCyc:MTBH37RV_PWY-6580 phosphatidylinositol biosynthesis I (bacteria)
BioCyc:BTHE_PWY4FS-8 phosphatidylglycerol biosynthesis II (non-plastidic)
PlantCyc:ARA_PWY-6352 3-phosphoinositide biosynthesis
Reactome:R-SPO-9612973 Autophagy
Reactome:R-HSA-9635486 Infection with Mycobacterium tuberculosis
Reactome:R-HSA-9637687 Suppression of phagosomal maturation
Reactome:R-HSA-9637690 Response of Mtb to phagocytosis
Reactome:R-HSA-9636569 Suppression of autophagy
Reactome:R-SCE-9612973 Autophagy
Reactome:R-HSA-9636383 Prevention of phagosomal-lysosomal fusion
Reactome:R-HSA-9824439 Bacterial Infection Pathways
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-556833 Metabolism of lipids
Reactome:R-BTA-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-1483255 PI Metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-BTA-1483255 PI Metabolism
Reactome:R-DRE-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-DDI-1483257 Phospholipid metabolism
Reactome:R-DDI-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-1483257 Phospholipid metabolism
Reactome:R-DME-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-RNO-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-SCE-1430728 Metabolism
Reactome:R-SCE-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-SPO-1483257 Phospholipid metabolism
Reactome:R-SPO-1483255 PI Metabolism
Reactome:R-SPO-1660516 Synthesis of PIPs at the early endosome membrane
Reactome:R-BTA-1483257 Phospholipid metabolism
Reactome:R-BTA-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DRE-556833 Metabolism of lipids
Reactome:R-DRE-1483255 PI Metabolism
Reactome:R-DDI-1483255 PI Metabolism
Reactome:R-DME-1483255 PI Metabolism
Reactome:R-HSA-1483257 Phospholipid metabolism
Reactome:R-HSA-1483255 PI Metabolism
Reactome:R-MMU-1483257 Phospholipid metabolism
Reactome:R-MMU-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-1483255 PI Metabolism
Reactome:R-SCE-1632852 Macroautophagy
Reactome:R-SCE-556833 Metabolism of lipids
Reactome:R-SCE-1483255 PI Metabolism
Reactome:R-SCE-1660516 Synthesis of PIPs at the early endosome membrane
Reactome:R-DRE-1483257 Phospholipid metabolism
Reactome:R-DRE-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-556833 Metabolism of lipids
Reactome:R-DDI-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-DME-556833 Metabolism of lipids
Reactome:R-DME-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-1483249 Inositol phosphate metabolism
Reactome:R-HSA-1855183 Synthesis of IP2, IP, and Ins in the cytosol
Reactome:R-HSA-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-HSA-1660517 Synthesis of PIPs at the late endosome membrane
Reactome:R-HSA-5663205 Infectious disease
Reactome:R-MMU-1660514 Synthesis of PIPs at the Golgi membrane
Reactome:R-RNO-1483257 Phospholipid metabolism
Reactome:R-RNO-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-SCE-1483257 Phospholipid metabolism
Reactome:R-SCE-1483248 Synthesis of PIPs at the ER membrane
Reactome:R-SCE-1660517 Synthesis of PIPs at the late endosome membrane
Reactome:R-SPO-556833 Metabolism of lipids
Reactome:R-SPO-1632852 Macroautophagy
WikiPathways:WP4971 Phosphoinositides metabolism
PathBank:SMP0087242 Inositol Metabolism
PathBank:SMP0087258 Phosphatidylinositol Phosphate Metabolism
PathBank:SMP0087410 Phosphatidylinositol Phosphate Metabolism
PathBank:SMP0120865 Joubert Syndrome
PathBank:SMP0087396 Inositol Metabolism
PathBank:SMP0087335 Inositol Metabolism
PathBank:SMP0087351 Phosphatidylinositol Phosphate Metabolism