EC: 1.1.1.37
malate dehydrogenase ((S)-malate:NAD+ oxidoreductase)
Pathways
| pathway id | name |
|---|---|
| BioCyc:HUMAN_MALATE-ASPARTATE-SHUTTLE-PWY | malate-aspartate shuttle |
| BioCyc:HUMAN_SERSYN-PWY | serine biosynthesis (phosphorylated route) |
| BioCyc:META_PWY-5690 | TCA cycle II (plants and fungi) |
| BioCyc:META_SER-GLYSYN-PWY | superpathway of L-serine and glycine biosynthesis I |
| BioCyc:META_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:ECO_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:ECO_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:ARA_PWYQT-4481 | TCA cycle variation V (plant) |
| BioCyc:ARA_PWY-7048 | malate-oxaloacetate shuttle II |
| BioCyc:ARA_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:MTBCDC1551_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:MTBCDC1551_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:ECOO157_TCA | TCA cycle I (prokaryotic) |
| BioCyc:ECOO157_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:CAULO_ANAEROFRUCAT-PWY | homolactic fermentation |
| BioCyc:CAULO_TCA | TCA cycle I (prokaryotic) |
| BioCyc:CAULO_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:CAULO_PWY-5481 | pyruvate fermentation to lactate |
| BioCyc:CAULO_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:CAULO_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:AGRO_PWY-7686 | L-malate degradation II |
| BioCyc:MOUSE_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:MOUSE_TCA-1 | TCA cycle |
| BioCyc:ECOL316407_TCA | TCA cycle I (prokaryotic) |
| BioCyc:CAULONA1000_P108-PWY | pyruvate fermentation to propionate I |
| BioCyc:HUMAN_PWY66-399 | gluconeogenesis |
| BioCyc:META_PWY-5464 | superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle |
| BioCyc:META_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:META_TCA | TCA cycle I (prokaryotic) |
| BioCyc:META_SERSYN-PWY | L-serine biosynthesis I |
| BioCyc:META_PWY-1622 | formaldehyde assimilation I (serine pathway) |
| BioCyc:ECO_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:YEAST_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:ARA_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:MTBH37RV_PWY-6969 | TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) |
| BioCyc:MTBH37RV_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:MTBH37RV_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:MTBCDC1551_P105-PWY | TCA cycle IV (2-oxoglutarate decarboxylase) |
| BioCyc:MTBCDC1551_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:MTBCDC1551_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:ECOO157_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:ECOO157_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:ECOO157_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:CAULO_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:ANTHRA_PWY-7686 | L-malate degradation II |
| BioCyc:AGRO_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:AGRO_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:AGRO_P108-PWY | pyruvate fermentation to propanoate I |
| BioCyc:MOUSE_PWY-5690-1 | TCA cycle variation III (eukaryotic) |
| BioCyc:BSUB_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:BSUB_ANARESP1-PWY | respiration (anaerobic) |
| BioCyc:BSUB_TCA | TCA cycle I (prokaryotic) |
| BioCyc:ECOL316407_ANARESP1-PWY | respiration (anaerobic) |
| BioCyc:ECOL316407_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:CAULONA1000_PWY-5913 | TCA cycle variation IV |
| BioCyc:CAULONA1000_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:CAULONA1000_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:BTHE_TCA | TCA cycle I (prokaryotic) |
| BioCyc:CORYNE_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:CORYNE_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:HUMAN_PWY66-407 | superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle |
| BioCyc:HUMAN_PWY66-398 | TCA cycle |
| BioCyc:META_PWY66-398 | TCA cycle III (animals) |
| BioCyc:META_PWY-6969 | TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) |
| BioCyc:META_MALATE-ASPARTATE-SHUTTLE-PWY | L-aspartate degradation II |
| BioCyc:META_PWY66-399 | gluconeogenesis III |
| BioCyc:META_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:ECO_TCA | TCA cycle I (prokaryotic) |
| BioCyc:ECO_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:YEAST_MALATE-ASPARTATE-SHUTTLE-PWY | aspartate degradation II |
| BioCyc:YEAST_GLUCONEO-YEAST-PWY | gluconeogenesis |
| BioCyc:ARA_PWY-7047 | malate-oxaloacetate shuttle I |
| BioCyc:ARA_PWY66-399 | gluconeogenesis III |
| BioCyc:MTBH37RV_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:MTBCDC1551_TCA | TCA cycle I (prokaryotic) |
| BioCyc:ECOO157_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:ANTHRA_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:AGRO_TCA | TCA cycle I (prokaryotic) |
| BioCyc:AGRO_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:MOUSE_MALATE-ASPARTATE-SHUTTLE-PWY | aspartate degradation II |
| BioCyc:BSUB_GLUCONEO-PWY-1 | gluconeogenesis I |
| BioCyc:ECOL316407_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:ECOL316407_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:CAULONA1000_PWY-561 | superpathway of glyoxylate cycle |
| BioCyc:CAULONA1000_PWY-1622 | formaldehyde assimilation I (serine pathway) |
| BioCyc:CAULONA1000_MALATE-ASPARTATE-SHUTTLE-PWY | aspartate degradation II |
| BioCyc:CAULONA1000_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:BTHE_P108-PWY | pyruvate fermentation to propionate I |
| BioCyc:BTHE_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:CORYNE_TCA | TCA cycle I (prokaryotic) |
| BioCyc:CORYNE_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:HUMAN_SER-GLYSYN-PWY | serine and glycine biosynthesis |
| BioCyc:META_PWY-561 | superpathway of glyoxylate cycle and fatty acid degradation |
| BioCyc:META_GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass |
| BioCyc:META_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:ECO_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:YEAST_PWY-5690 | TCA cycle II (plants and fungi) |
| BioCyc:ARA_PWY-5690 | TCA cycle II (plants and fungi) |
| BioCyc:ARA_MALATE-ASPARTATE-SHUTTLE-PWY | L-aspartate degradation II |
| BioCyc:ARA_PWY-561 | superpathway of glyoxylate cycle and fatty acid degradation |
| BioCyc:MTBCDC1551_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:MTBCDC1551_PWY-6969 | TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) |
| BioCyc:ECOO157_ANARESP1-PWY | respiration (anaerobic) |
| BioCyc:ECOO157_MALATE-ASPARTATE-SHUTTLE-PWY | aspartate degradation II |
| BioCyc:CAULO_ANARESP1-PWY | respiration (anaerobic) |
| BioCyc:AGRO_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:AGRO_FERMENTATION-PWY | mixed acid fermentation |
| BioCyc:ECOL316407_GLYOXYLATE-BYPASS | glyoxylate cycle |
| BioCyc:ECOL316407_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| BioCyc:CAULONA1000_ANARESP1-PWY | respiration (anaerobic) |
| BioCyc:BTHE_GLUCONEO-PWY | gluconeogenesis I |
| BioCyc:BTHE_MALATE-ASPARTATE-SHUTTLE-PWY | aspartate degradation II |
| BioCyc:CORYNE_TCA-GLYOX-BYPASS | superpathway of glyoxylate bypass and TCA |
| PathBank:SMP0000802 | TCA Cycle |
| PathBank:SMP0000983 | Secondary Metabolites: Glyoxylate Cycle |
| PathBank:SMP0001018 | TCA cycle (ubiquinol-2) |
| PathBank:SMP0001019 | TCA cycle (ubiquinol-3) |
| PathBank:SMP0001020 | TCA cycle (ubiquinol-4) |
| PathBank:SMP0001021 | TCA cycle (ubiquinol-5) |
| PathBank:SMP0001022 | TCA cycle (ubiquinol-6) |
| PathBank:SMP0001023 | TCA cycle (ubiquinol-7) |
| PathBank:SMP0001024 | TCA cycle (ubiquinol-8) |
| PathBank:SMP0001025 | TCA cycle (ubiquinol-9) |
| PathBank:SMP0001026 | TCA cycle (ubiquinol-10) |
| PathBank:SMP0002037 | TCA cycle (ubiquinol-0) |
| PlantCyc:ARA_PWY-5464 | superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle |
| PlantCyc:ARA_PWY66-399 | gluconeogenesis III |
| PlantCyc:ARA_GLUCONEO-PWY | gluconeogenesis I |
| PlantCyc:ARA_PWY-561 | superpathway of glyoxylate cycle and fatty acid degradation |
| PlantCyc:PLANT_PWYQT-4481 | TCA cycle variation V (plant) |
| PlantCyc:PLANT_PWY-7047 | malate-oxaloacetate shuttle I |
| PlantCyc:ARA_PWYQT-4481 | TCA cycle variation V (plant) |
| PlantCyc:ARA_GLYOXYLATE-BYPASS | glyoxylate cycle |
| PlantCyc:ARA_PWY-5690 | TCA cycle II (plants and fungi) |
| PlantCyc:PLANT_PWY-5690 | TCA cycle II (plants and fungi) |
| PlantCyc:PLANT_GLYOXYLATE-BYPASS | glyoxylate cycle |
| PlantCyc:ARA_MALATE-ASPARTATE-SHUTTLE-PWY | L-aspartate degradation II |
| PlantCyc:ARA_PWY-7048 | malate-oxaloacetate shuttle II |
| PlantCyc:ARA_PWY-7047 | malate-oxaloacetate shuttle I |
| PlantCyc:PLANT_PWY-7048 | malate-oxaloacetate shuttle II |
| PlantCyc:PLANT_PWY-5464 | superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle |
| PlantCyc:PLANT_PWY-561 | superpathway of glyoxylate cycle and fatty acid degradation |
| Reactome:R-SSC-9856872 | Malate-aspartate shuttle |
| Reactome:R-HSA-9856872 | Malate-aspartate shuttle |
| Reactome:R-SCE-9856872 | Malate-aspartate shuttle |
| Reactome:R-SPO-9856872 | Malate-aspartate shuttle |
| Reactome:R-XTR-9856872 | Malate-aspartate shuttle |
| Reactome:R-DDI-9856872 | Malate-aspartate shuttle |
| Reactome:R-MMU-9856872 | Malate-aspartate shuttle |
| Reactome:R-RNO-9856872 | Malate-aspartate shuttle |
| Reactome:R-BTA-9856872 | Malate-aspartate shuttle |
| Reactome:R-CEL-9856872 | Malate-aspartate shuttle |
| Reactome:R-BTA-1430728 | Metabolism |
| Reactome:R-BTA-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-BTA-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-CEL-611105 | Respiratory electron transport |
| Reactome:R-GGA-1660598 | Metabolism |
| Reactome:R-GGA-352875 | Gluconeogenesis |
| Reactome:R-HSA-611105 | Respiratory electron transport |
| Reactome:R-MMU-1430728 | Metabolism |
| Reactome:R-MMU-611105 | Respiratory electron transport |
| Reactome:R-RNO-611105 | Respiratory electron transport |
| Reactome:R-SCE-611105 | Respiratory electron transport |
| Reactome:R-SPO-1430728 | Metabolism |
| Reactome:R-SPO-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-SPO-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-BTA-611105 | Respiratory electron transport |
| Reactome:R-HSA-977347 | Serine metabolism |
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SPO-611105 | Respiratory electron transport |
| Reactome:R-SSC-1430728 | Metabolism |
| Reactome:R-SSC-977347 | Serine metabolism |
| Reactome:R-XTR-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-CEL-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-CEL-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-DDI-611105 | Respiratory electron transport |
| Reactome:R-GGA-353098 | Carbohydrate metabolism |
| Reactome:R-HSA-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-HSA-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-HSA-71291 | Amino acid and derivative metabolism |
| Reactome:R-MMU-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-MMU-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-RNO-1430728 | Metabolism |
| Reactome:R-RNO-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-RNO-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-SCE-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-SCE-71403 | Citric acid cycle (TCA cycle) |
| Reactome:R-SSC-611105 | Respiratory electron transport |
| Reactome:R-SSC-71291 | Amino acid and derivative metabolism |
| Reactome:R-XTR-1430728 | Metabolism |
| Reactome:R-CEL-1430728 | Metabolism |
| Reactome:R-DDI-1430728 | Metabolism |
| Reactome:R-DDI-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-HSA-1430728 | Metabolism |
| Reactome:R-SSC-1428517 | Aerobic respiration and respiratory electron transport |
| Reactome:R-XTR-611105 | Respiratory electron transport |
| WikiPathways:WP4595 | Urea cycle and associated pathways |
| WikiPathways:WP2624 | TCA cycle (Krebs cycle) |
| WikiPathways:WP4688 | Serine metabolism |
| WikiPathways:WP5355 | Metabolic Epileptic Disorders |
| WikiPathways:WP5220 | Metabolic reprogramming in pancreatic cancer |
| WikiPathways:WP2621 | Glycolysis |
| WikiPathways:WP5312 | Metabolic pathways of fibroblasts |
| PathBank:SMP0120488 | Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease |
| PathBank:SMP0120637 | Glycogenosis, Type IB |
| PathBank:SMP0120645 | Glycogenosis, Type IA. Von Gierke Disease |
| PathBank:SMP0121182 | Citrate Cycle |
| PathBank:SMP0000129 | Malate-Aspartate Shuttle |
| PathBank:SMP0000334 | Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) |
| PathBank:SMP0000242 | Dimethylglycine Dehydrogenase Deficiency |
| PathBank:SMP0000374 | Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease |
| PathBank:SMP0000223 | Non-Ketotic Hyperglycinemia |
| PathBank:SMP0000484 | Dimethylglycine Dehydrogenase Deficiency |
| PathBank:SMP0000548 | Mitochondrial Complex II Deficiency |
| PathBank:SMP0000560 | Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) |
| PathBank:SMP0002302 | Aspartate Metabolism |
| PathBank:SMP0002413 | Gluconeogenesis from L-Malic Acid |
| PathBank:SMP0087254 | Transfer of Acetyl Groups into Mitochondria |
| PathBank:SMP0087270 | Warburg Effect |
| PathBank:SMP0087438 | Malate-Aspartate Shuttle |
| PathBank:SMP0063661 | Pyruvate Metabolism |
| PathBank:SMP0120531 | Pyruvate Dehydrogenase Complex Deficiency |
| PathBank:SMP0120624 | Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) |
| PathBank:SMP0120922 | LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0120946 | LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0000004 | Glycine and Serine Metabolism |
| PathBank:SMP0000196 | Leigh Syndrome |
| PathBank:SMP0000547 | Fumarase Deficiency |
| PathBank:SMP0000551 | Pyruvate Dehydrogenase Deficiency (E2) |
| PathBank:SMP0000559 | Pyruvate Kinase Deficiency |
| PathBank:SMP0000563 | Triosephosphate Isomerase Deficiency |
| PathBank:SMP0000721 | 3-Phosphoglycerate Dehydrogenase Deficiency |
| PathBank:SMP0002336 | Glyoxylate Cycle |
| PathBank:SMP0087204 | Malate-Aspartate Shuttle |
| PathBank:SMP0087449 | Pyruvate Metabolism |
| PathBank:SMP0063617 | Gluconeogenesis |
| PathBank:SMP0120533 | Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) |
| PathBank:SMP0120622 | Primary Hyperoxaluria II, PH2 |
| PathBank:SMP0120626 | Fructose-1,6-diphosphatase Deficiency |
| PathBank:SMP0120638 | Glycogenosis, Type IC |
| PathBank:SMP0000057 | Citric Acid Cycle |
| PathBank:SMP0000128 | Gluconeogenesis |
| PathBank:SMP0000212 | Pyruvate Dehydrogenase Complex Deficiency |
| PathBank:SMP0000179 | Dihydropyrimidine Dehydrogenase Deficiency (DHPD) |
| PathBank:SMP0000485 | Hyperglycinemia, Non-Ketotic |
| PathBank:SMP0000549 | 2-Ketoglutarate Dehydrogenase Complex Deficiency |
| PathBank:SMP0000573 | Glycogenosis, Type IB |
| PathBank:SMP0000581 | Glycogenosis, Type IA. Von Gierke Disease |
| PathBank:SMP0000654 | Warburg Effect |
| PathBank:SMP0087223 | Gluconeogenesis |
| PathBank:SMP0087231 | Pyruvate Metabolism |
| PathBank:SMP0087492 | Transfer of Acetyl Groups into Mitochondria |
| PathBank:SMP0063636 | Malate-Aspartate Shuttle |
| PathBank:SMP0100046 | LPS and Citrate Signaling and Inflammation |
| PathBank:SMP0120506 | Leigh Syndrome |
| PathBank:SMP0120623 | Pyruvate Kinase Deficiency |
| PathBank:SMP0120627 | Triosephosphate Isomerase Deficiency |
| PathBank:SMP0000060 | Pyruvate Metabolism |
| PathBank:SMP0000466 | Transfer of Acetyl Groups into Mitochondria |
| PathBank:SMP0000244 | Sarcosinemia |
| PathBank:SMP0000546 | Congenital Lactic Acidosis |
| PathBank:SMP0000550 | Pyruvate Dehydrogenase Deficiency (E3) |
| PathBank:SMP0000558 | Primary Hyperoxaluria II, PH2 |
| PathBank:SMP0000562 | Fructose-1,6-diphosphatase Deficiency |
| PathBank:SMP0000574 | Glycogenosis, Type IC |
| PathBank:SMP0002304 | TCA Cycle |
| PathBank:SMP0002422 | Aspartate Metabolism |
| PathBank:SMP0086930 | Warburg Effect |
| PathBank:SMP0087527 | Warburg Effect |
| PathBank:SMP0063681 | Transfer of Acetyl Groups into Mitochondria |