Pathways Knowlegdes
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| Pathway | DOIs | Note |
|---|---|---|
| superpathway of phenylalanine, tyrosine and tryptophan biosynthesis Accession ID: BioCyc:CALBI_COMPLETE-ARO-PWY |
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| tetrahydrofolate biosynthesis Accession ID: BioCyc:CALBI_PWY-3742 |
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Cossins EA, Chen L. Folates and one-carbon metabolism in plants and fungi. Phytochemistry. 1997 Jun;45(3):437–52. doi: 10.1016/s0031-9422(96)00833-3. PMID: 9190084.; Daly S, Mastromei G, Yacoub A, Lorenzetti R. Sequence of a dihydrofolate reductase-encoding gene from Candida albicans. Gene. 1994 Sep 15;147(1):115–8. doi: 10.1016/0378-1119(94)90049-3. PMID: 7916311. |
| tryptophan biosynthesis Accession ID: BioCyc:CALBI_TRPSYN-PWY |
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Kingsbury JM, Goldstein AL, McCusker JH. Role of Nitrogen and Carbon Transport, Regulation, and Metabolism Genes for Saccharomyces cerevisiae Survival In Vivo. Eukaryot Cell. 2006 May;5(5):816–24. doi: 10.1128/ec.5.5.816-824.2006.; Toyn JH, Gunyuzlu PL, White WH, Thompson LA, Hollis GF. A counterselection for the tryptophan pathway in yeast: 5-fluoroanthranilic acid resistance. Yeast. 2000 Apr;16(6):553–60. doi: 10.1002/(sici)1097-0061(200004)16:6<553::aid-yea554>3.0.co;2-7. PMID: 10790693.; Graf R, Mehmann B, Braus GH. Analysis of feedback-resistant anthranilate synthases from Saccharomyces cerevisiae. J Bacteriol. 1993 Feb;175(4):1061–8. doi: 10.1128/jb.175.4.1061-1068.1993.; Braus GH. Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway. Microbiol Rev. 1991 Sep;55(3):349–70. doi: 10.1128/mr.55.3.349-370.1991.; Zalkin H, Paluh JL, van Cleemput M, Moye WS, Yanofsky C. Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase. Journal of Biological Chemistry. 1984 Mar;259(6):3985–92. doi: 10.1016/s0021-9258(17)43193-0. |
| chorismate biosynthesis Accession ID: BioCyc:CALBI_ARO-PWY |
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Sousa S, McLaughlin MM, Pereira SA, VanHorn S, Knowlton R, Brown JR, Nicholas RO, Livi GP. The ARO4 gene of Candida albicans encodes a tyrosine-sensitive DAHP synthase: evolution, functional conservation and phenotype of Aro3p-, Aro4p-deficient mutants The GenBank accession number for the sequence reported in this paper is U53216. 2002 May 01;148(5):1291–303. doi: 10.1099/00221287-148-5-1291.; Henstrand JM, Schaller A, Braun M, Amrhein N, Schmid J. Saccharomyces cerevisiae chorismate synthase has a flavin reductase activity. Molecular Microbiology. 1996 Dec;22(5):859–66. doi: 10.1046/j.1365-2958.1996.01534.x.; Pereira SA, Livi GP. Aromatic amino-acid biosynthesis in Candida albicans: identification of the ARO4 gene encoding a second DAHP synthase. Curr Genet. 1996 Apr;29(5):441–5. doi: 10.1007/bf02221512. PMID: 8625423.; Derrick S, Large PJ. Activities of the enzymes of the Ehrlich pathway and formation of branched-chain alcohols in Saccharomyces cerevisiae and Candida utilis grown in continuous culture on valine or ammonium as sole nitrogen source. Journal of General Microbiology. 1993 Nov 01;139(11):2783–92. doi: 10.1099/00221287-139-11-2783.; Pereira SA, Livi GP. Cloning and expression of the ARO3 gene encoding DAHP synthase from Candida albicans. Gene. 1993 Oct 15;132(2):159–65. doi: 10.1016/0378-1119(93)90191-5. PMID: 7901125.; Jones DGL, Reusser U, Braus GH. Molecular cloning, characterization and analysis of the regulation of the AR02 gene, encoding chorismate synthase, of Saccharomyces cerevisiae. Molecular Microbiology. 1991 Sep;5(9):2143–53. doi: 10.1111/j.1365-2958.1991.tb02144.x. |
| tyrosine biosynthesis Accession ID: BioCyc:CALBI_PWY3O-4120 |
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Kingsbury JM, Goldstein AL, McCusker JH. Role of Nitrogen and Carbon Transport, Regulation, and Metabolism Genes for Saccharomyces cerevisiae Survival In Vivo. Eukaryot Cell. 2006 May;5(5):816–24. doi: 10.1128/ec.5.5.816-824.2006.; Urrestarazu A, Vissers S, Iraqui I, Grenson M. Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination. Molecular Genetics and Genomics. 1998 Jan;257(2):230–7. doi: 10.1007/s004380050643.; Braus GH. Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway. Microbiol Rev. 1991 Sep;55(3):349–70. doi: 10.1128/mr.55.3.349-370.1991.; BODE R, MELO C, BIRNBAUM D. Absolute Dependence of Phenylalanine and Tyrosine Biosynthetic Enzyme on Tryptophan inCandida maltosa. Hoppe-Seyler´s Zeitschrift für physiologische Chemie. 1984 Jan;365(2):799–804. doi: 10.1515/bchm2.1984.365.2.799.; Kradolfer P, Niederberger P, Hütter R. Tryptophan degradation in Saccharomyces cerevisiae: characterization of two aromatic aminotransferases. Arch Microbiol. 1982 Dec 11;133(3):242–8. doi: 10.1007/bf00415010. PMID: 6763508. |
| ubiquinone (coenzyme Q) biosynthesis Accession ID: BioCyc:CALBI_PWY3B3-10 |
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| phenylalanine biosynthesis Accession ID: BioCyc:CALBI_PHESYN |
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Kingsbury JM, Goldstein AL, McCusker JH. Role of Nitrogen and Carbon Transport, Regulation, and Metabolism Genes for Saccharomyces cerevisiae Survival In Vivo. Eukaryot Cell. 2006 May;5(5):816–24. doi: 10.1128/ec.5.5.816-824.2006.; Braus GH. Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway. Microbiol Rev. 1991 Sep;55(3):349–70. doi: 10.1128/mr.55.3.349-370.1991.; Bode R, Birnbaum D. Regulation of chorismate mutase activity of various yeast species by aromatic amino acids. Antonie Van Leeuwenhoek. 1991 Jan;59(1):9–13. doi: 10.1007/bf00582113. PMID: 2059012.; BODE R, MELO C, BIRNBAUM D. Absolute Dependence of Phenylalanine and Tyrosine Biosynthetic Enzyme on Tryptophan inCandida maltosa. Hoppe-Seyler´s Zeitschrift für physiologische Chemie. 1984 Jan;365(2):799–804. doi: 10.1515/bchm2.1984.365.2.799. |
| Acetaminophen synthesis Accession ID: WikiPathways:WP2886 |
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Mizutani Y, Narikawa T, Satoh T, Sakurai N, Kaji H, Yamada S, Samejima T. A new UV method for serum gamma-glutamyltransferase assay using recombinant 4-aminobenzoate hydroxylase as a coupling enzyme. J Biochem. 1999 Aug;126(2):347–53. doi: 10.1093/oxfordjournals.jbchem.a022456. PMID: 10423528. |
| 2,3-Dihydroxybenzoate Biosynthesis Accession ID: PathBank:SMP0000774 |
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| Biosynthesis of Siderophore Group Nonribosomal Peptides Accession ID: PathBank:SMP0000783 |
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| Tyrosine Biosynthesis Accession ID: PathBank:SMP0000826 |
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| Phenylalanine Biosynthesis Accession ID: PathBank:SMP0000827 |
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| Tryptophan Metabolism Accession ID: PathBank:SMP0000835 |
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| Chorismate Biosynthesis Accession ID: PathBank:SMP0000836 |
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| Folate Biosynthesis Accession ID: PathBank:SMP0000925 |
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| Phenylalanine Metabolism Accession ID: PathBank:SMP0000938 |
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| Secondary Metabolites: Ubiquinol Biosynthesis Accession ID: PathBank:SMP0000997 |
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| Menaquinol Biosythesis Accession ID: PathBank:SMP0001911 |
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| Tryptophan Metabolism II Accession ID: PathBank:SMP0001930 |
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| Secondary Metabolites: Ubiquinol Biosynthesis 2 Accession ID: PathBank:SMP0002050 |
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