chorismate biosynthesis

Sousa S, McLaughlin MM, Pereira SA, VanHorn S, Knowlton R, Brown JR, Nicholas RO, Livi GP. The ARO4 gene of Candida albicans encodes a tyrosine-sensitive DAHP synthase: evolution, functional conservation and phenotype of Aro3p-, Aro4p-deficient mutants The GenBank accession number for the sequence reported in this paper is U53216. 2002 May 01;148(5):1291–303. doi: 10.1099/00221287-148-5-1291.; Henstrand JM, Schaller A, Braun M, Amrhein N, Schmid J. Saccharomyces cerevisiae chorismate synthase has a flavin reductase activity. Molecular Microbiology. 1996 Dec;22(5):859–66. doi: 10.1046/j.1365-2958.1996.01534.x.; Pereira SA, Livi GP. Aromatic amino-acid biosynthesis in Candida albicans: identification of the ARO4 gene encoding a second DAHP synthase. Curr Genet. 1996 Apr;29(5):441–5. doi: 10.1007/bf02221512. PMID: 8625423.; Derrick S, Large PJ. Activities of the enzymes of the Ehrlich pathway and formation of branched-chain alcohols in Saccharomyces cerevisiae and Candida utilis grown in continuous culture on valine or ammonium as sole nitrogen source. Journal of General Microbiology. 1993 Nov 01;139(11):2783–92. doi: 10.1099/00221287-139-11-2783.; Pereira SA, Livi GP. Cloning and expression of the ARO3 gene encoding DAHP synthase from Candida albicans. Gene. 1993 Oct 15;132(2):159–65. doi: 10.1016/0378-1119(93)90191-5. PMID: 7901125.; Jones DGL, Reusser U, Braus GH. Molecular cloning, characterization and analysis of the regulation of the AR02 gene, encoding chorismate synthase, of Saccharomyces cerevisiae. Molecular Microbiology. 1991 Sep;5(9):2143–53. doi: 10.1111/j.1365-2958.1991.tb02144.x.

Metabolites

ADP

Formula: C10H15N5O10P2 (427.02941500000003)

CAS ID: 58-64-0

ATP

Formula: C10H16N5O13P3 (506.9957476)

CAS ID: 56-65-5

Chorismate

Formula: C10H10O6 (226.04773600000001)

CAS ID: 617-12-9

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

NADPH

Formula: C21H30N7O17P3 (745.0911)

CAS ID: 2646-71-1

Orthophosphate

Formula: H3PO4 (97.9768968)

CAS ID: 7664-38-2

Phosphoenolpyruvate

Formula: C3H5O6P (167.98237600000002)

CAS ID: 138-08-9



Enzyme

EC Number name full name note


Proteins

Protein ID name full name