Metabolite List
all metabolites that has the same formula 'C20H27O2'
retinoate (BioCAD00000472693)
Formula: C20H27O2 (Exact Mass: 299.2011)
All-trans-retinoate is a retinoate that is the conjugate base of all-trans-retinoic acid. It has a role as a human metabolite. It is a conjugate base of an all-trans-retinoic acid. An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
all-trans-retinoate (BioCAD00000472694)
Formula: C20H27O2 (Exact Mass: 299.2011)
A retinoate that is the conjugate base of all-trans-retinoic acid." []
9-cis-retinoate (BioCAD00000472696)
Formula: C20H27O2 (Exact Mass: 299.2011)
A retinoate that is the conjugate base of 9-cis-retinoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3." []
11-cis-retinoate (BioCAD00000472697)
Formula: C20H27O2 (Exact Mass: 299.2011)
A retinoate that is the conjugate base of 11-cis-retinoic acid, obtaained by deprotonation of the carboxy group; major species at pH 7.3." []
dehydroabietate (BioCAD00000472765)
Formula: C20H27O2 (Exact Mass: 299.2011)
A monocarboxylic acid anion that is the conjugate base of dehydroabietic acid, obtained by deprotonation of the carboxy group." []
2,6-Di-Tert-Butyl-4-(4-Methoxy-Phenyl)-Pyranylium (BioCAD00000564377)
Formula: C20H27O2 (Exact Mass: 299.2011)
a retinoate (BioCAD00000762749)
Formula: C20H27O2 (Exact Mass: 299.2011)
Retinoic acids comprise a biologically active form of retinoids (vitamin A and its derivatives). The spatiotemporal gradient of RA is essential for the regulation of cell proliferation and the differentiation and organ development.There are three stereoisomeric forms of retinoic acid: |FRAME: RETINOATE|, |FRAME: CPD-13549|, and |FRAME: CPD-13548|, which show different binding affinities to the retinoic acid receptors.|FRAME: RETINOATE| is known to bind exclusively to the nuclear retinoic acid receptors (RARs), whereas |FRAME: CPD-13549| binds to both RARs and retinoid x-receptors (RXRs). |FRAME: CPD-13548| is naturally generated in the body, yet it has a 100-fold lower affinity to RARs than |FRAME: RETINOATE| or |FRAME: CPD-13549|, and it does not bind to RXRs.
13-cis-retinoate (BioCAD00000774605)
Formula: C20H27O2 (Exact Mass: 299.2011)
There are three stereoisomeric forms of retinoic acid: |FRAME: RETINOATE|, |FRAME: CPD-13549|, and |FRAME: CPD-13548|, which show different binding affinities to the retinoic acid receptors. |FRAME: CPD-13548| is naturally generated in the body, yet it has a 100-fold lower affinity to the nuclear retinoic acid receptors than |FRAME: RETINOATE| or |FRAME: CPD-13549|, and it does not bind to retinoid x-receptors. Thus, the mechanism of action of |FRAME: CPD-13548| is still unclear.It has been suggested that |FRAME: CPD-13548| modulates brain neurochemical systems because increased levels are correlated with depression and increased suicidal tendencies |CITS: [17707566]|.