Disorders of transmembrane transporters

Dean M. The genetics of ATP-binding cassette transporters. Methods Enzymol. 2005;400():409–29. doi: 10.1016/s0076-6879(05)00024-8. PMID: 16399363.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

Choline

Formula: C5H14NO (104.10753340000001)

CAS ID: 62-49-7

Cl-

Formula: Cl (34.968853)

CAS ID: 16887-00-6

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

D-Glucose

Formula: C6H12O6 (180.0633852)

CAS ID: 50-99-7

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

Fe3+

Formula: Fe (55.934939)

CAS ID: 7439-89-6

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

HCO3-

Formula: HCO3 (60.9925696)

CAS ID: 71-52-3

Iodide

Formula: I (126.904477)

CAS ID: 20461-54-5

L-Carnitine

Formula: C7H15NO3 (161.105188)

CAS ID: 541-15-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Porphyrin

Formula: C20H14N4 (310.1218404)

CAS ID: 101-60-0

Potassium cation

Formula: K (38.963708)

CAS ID: 24203-36-9

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

Sulfate

Formula: H2SO4 (97.9673812)

CAS ID: 7664-93-9

Urate

Formula: C5H4N4O3 (168.0283394)

CAS ID: 69-93-2

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

Ivacaftor

Formula: C24H28N2O3 (392.20998180000004)

CAS ID: 873054-44-5

L-argininium(1+)

Formula: C6H15N4O2 (175.119495)

CAS ID: 17806-42-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.2.-
1.11.1.27 glutathione-dependent peroxiredoxin glutathione:hydroperoxide oxidoreductase
1.11.1.9 glutathione peroxidase glutathione:hydrogen-peroxide oxidoreductase
1.16.3.1 ferroxidase Fe(II):oxygen oxidoreductase
1.16.3.4 cuproxidase copper(I):oxygen oxidoreductase
2.7.1.1 hexokinase ATP:D-hexose 6-phosphotransferase
3.6.4.6 vesicle-fusing ATPase ATP phosphohydrolase (vesicle-fusing)
5.6.1.6 channel-conductance-controlling ATPase ATP phosphohydrolase (channel-conductance-controlling)
7.6.2.3 ABC-type glutathione-S-conjugate transporter ATP + H2O + glutathione-S-conjugate[side 1] = ADP + phosphate + glutathione-S-conjugate[side 2]
7.6.2.8 ABC-type vitamin B12 transporter ATP phosphohydrolase (ABC-type, vitamin B12-importing)


Proteins

Protein ID name full name