Chorismate (BioCAD00000008448)

plant natural products microbial natural products

Metabolite Card

Formula: C10H10O6 (226.0477)
SMILES: O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O

Synonyms [en]

Chorismic acid; chorismate; (3R-trans)-3-((1-Carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid; (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid; (3R,4R)-3-[(1-carboxyvinyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid; (3R,4R)-3-[(1-Carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Chorismate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000008448). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and microorganisms. It is a precursor for the aromatic amino acids phenylalanine and tyrosine,indole, indole derivatives and tryptophan,2,3-dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis,the plant hormone salicylic acid and many alkaloids and other aromatic metabolites. -- Wikipedia.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 55508-12-8
  • CAS Registry Number: 617-12-9
  • PubChem: 12039
  • ChEBI: ChEBI:17333
  • HMDB: HMDB0012199
  • HMDB: HMDB12199
  • KEGG: C00251
  • NCBI MeSH: Chorismic Acid
  • Wikipedia: Chorismic_acid
  • RefMet: RM0153397
  • MoNA: RP011401
  • MoNA: RP011402
  • MoNA: RP011403
  • Metlin: METLIN_368
  • Metlin: METLIN_62850
  • Coconut NaturalProduct: CNP0259922.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00985 4.1.3.27 chorismate pyruvate-lyase (amino-accepting; anthranilate-forming)
KEGG:R00986 4.1.3.27 chorismate pyruvate-lyase (amino-accepting)
KEGG:R01302 4.1.3.40 chorismate pyruvate-lyase (4-hydroxybenzoate-forming)
KEGG:R01714 4.2.3.5 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)
KEGG:R01715 5.4.99.5 chorismate pyruvatemutase
KEGG:R01716 2.6.1.85 chorismate:L-glutamine aminotransferase
KEGG:R01717 5.4.4.2 chorismate hydroxymutase
KEGG:R05552 2.6.1.85 C00251 + C00014<=>C11355 + C00001
KEGG:R06603 C00251<=>C00805 + C00022
KEGG:R08956 2.6.1.86 (2S)-2-amino-4-deoxychorismate:L-glutamate aminotransferase
KEGG:R10583 3.3.2.13 chorismate pyruvate-hydrolase
KEGG:R10597 4.1.3.45 chorismate pyruvate-lyase (3-hydroxybenzoate-forming)
KEGG:R10666 4.2.1.151 chorismate hydro-lyase (3-[(1-carboxyvinyl)oxy]benzoate-forming)
KEGG:R12937 2.6.1.123 C00251 + C00014<=>C18054 + C00001
KEGG:R12939 2.6.1.123 chorismate:L-glutamine aminotransferase (2-amino-4-deoxychorismate-forming)
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]
  2. Bacillus subtilis [ncbi taxid: 1423]
  3. Catharanthus roseus [ncbi taxid: 4058]
  4. Escherichia coli [ncbi taxid: 562]
  5. Galium mollugo [ncbi taxid: 254777]
  6. Klebsiella pneumonia [ncbi taxid: ]
  7. Pseudomonas sp. [ncbi taxid: 306]
  8. Saccharomyces cerevisiae [ncbi taxid: 4932]
  9. Streptomyces [ncbi taxid: 1883]
  10. Streptomyces 3022a [ncbi taxid: ]
  11. Streptomyces aminophilus [ncbi taxid: ]
  12. Streptomyces antibioticus [ncbi taxid: 1890]
  13. Streptomyces coelicolor [ncbi taxid: 1902]
  14. Streptomyces coelicolor A3(2) [ncbi taxid: 100226]
  15. Streptomyces griseus [ncbi taxid: 1911]
  16. Streptomyces hygroscopicus [ncbi taxid: 1912]

Pathway Synthetic

pathway id name
BioCyc:CALBI_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
BioCyc:CALBI_PWY-3742 tetrahydrofolate biosynthesis
BioCyc:CALBI_TRPSYN-PWY tryptophan biosynthesis
BioCyc:CALBI_ARO-PWY chorismate biosynthesis
BioCyc:CALBI_PWY3O-4120 tyrosine biosynthesis
BioCyc:CALBI_PWY3B3-10 ubiquinone (coenzyme Q) biosynthesis
BioCyc:CALBI_PHESYN phenylalanine biosynthesis
WikiPathways:WP2886 Acetaminophen synthesis
PathBank:SMP0000774 2,3-Dihydroxybenzoate Biosynthesis
PathBank:SMP0000783 Biosynthesis of Siderophore Group Nonribosomal Peptides
PathBank:SMP0000826 Tyrosine Biosynthesis
PathBank:SMP0000827 Phenylalanine Biosynthesis
PathBank:SMP0000835 Tryptophan Metabolism
PathBank:SMP0000836 Chorismate Biosynthesis
PathBank:SMP0000925 Folate Biosynthesis
PathBank:SMP0000938 Phenylalanine Metabolism
PathBank:SMP0000997 Secondary Metabolites: Ubiquinol Biosynthesis
PathBank:SMP0001911 Menaquinol Biosythesis
PathBank:SMP0001930 Tryptophan Metabolism II
PathBank:SMP0002050 Secondary Metabolites: Ubiquinol Biosynthesis 2
View All Pathways