Dihydroceramide (BioCAD00000020829)

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Metabolite Card

Formula: C19H39NO3 (329.293)
SMILES: CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC=O

Synonyms [en]

Dihydroceramide; N-Acylsphinganine; N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]formamide; 3R)-1; Q63153308; 3-dihydroxyoctadecan-2-ylformamide

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Dihydroceramide. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000020829). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Dihydroceramide is an intermediate in sphingolipid metabolism. Dihydroceramide is the third to last step in the synthesis of beta-D-Galactosyl-1,4-beta-D glucosylceramide and is converted from sphinganine via the enzyme acyl-CoA-dependent ceramide synthase (EC 2.3.1.24). It is then converted to N-acylsphingosine via the enzyme fatty acid desaturase (EC 1.14.-.-).

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • PubChem: 16755624
  • ChEBI: ChEBI:31488
  • HMDB: HMDB0006752
  • HMDB: HMDB06752
  • KEGG: C12126
  • NCBI MeSH: dihydroceramide
  • Metlin: METLIN_58540
  • Coconut NaturalProduct: CNP0154914.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:YEAST_PWY-7119 sphingolipid recycling and degradation (yeast)
BioCyc:FLY_PWY3DJ-12 ceramide de novo biosynthesis
BioCyc:THAPS_PWY3DJ-12 ceramide biosynthesis
BioCyc:ARA_PWY-5129 sphingolipid biosynthesis (plants)
BioCyc:HUMAN_PWY3DJ-12 ceramide de novo biosynthesis
BioCyc:META_PWY-7119 sphingolipid recycling and degradation (yeast)
BioCyc:META_PWY-5129 sphingolipid biosynthesis (plants)
BioCyc:MOUSE_PWY3DJ-12 ceramide biosynthesis
BioCyc:META_PWY-7277 sphingolipid biosynthesis (mammals)
BioCyc:META_PWY3DJ-12 ceramide de novo biosynthesis
WikiPathways:WP1422 Sphingolipid pathway
WikiPathways:WP3232 Sphingolipid metabolism
WikiPathways:WP5194 Synthesis of ceramides and 1-deoxyceramides
WikiPathways:WP4142 Metabolism of sphingolipids in ER and Golgi apparatus
PathBank:SMP0120702 Globoid Cell Leukodystrophy
PathBank:SMP0120738 Metachromatic Leukodystrophy (MLD)
PathBank:SMP0120810 Krabbe Disease
PathBank:SMP0000349 Gaucher Disease
PathBank:SMP0002378 Sphingolipid Metabolism
PathBank:SMP0087398 Sphingolipid Metabolism
View All Pathways