Synthesis of ceramides and 1-deoxyceramides

Sen P, Hyötyläinen T, Orešic M. 1-Deoxyceramides - Key players in lipotoxicity and progression to type 2 diabetes? Acta Physiol (Oxf). 2021 May;232(1):e13635. doi: 10.1111/apha.13635. PMID: 33630410.

Metabolites

3-Dehydrosphinganine

Formula: C18H37NO2 (299.2824142)

CAS ID: 16105-69-4

Alanine

Formula: C3H7NO2 (89.0476762)

CAS ID: 302-72-7

Ethanolamine phosphate

Formula: C2H8NO4P (141.0190938)

CAS ID: 1071-23-4

Hexadecenal

Formula: C16H30O (238.22965299999998)

CAS ID: 3163-37-9

Palmitoyl-CoA

Formula: C37H66N7O17P3S (1005.3448576)

CAS ID: 1763-10-6

Serine

Formula: C3H7NO3 (105.0425912)

CAS ID: 302-84-1

Sphinganine

Formula: C18H39NO2 (301.2980634)

CAS ID: 764-22-7

Sphingosine

Formula: C18H37NO2 (299.2824142)

CAS ID: 123-78-4

Sphingosine 1-phosphate

Formula: C18H38NO5P (379.24874680000005)

CAS ID: 26993-30-6

Dihydroceramide

Formula: C19H39NO3 (329.29297840000004)

CAS ID:



Enzyme

EC Number name full name note
2.3.1.50 serine C-palmitoyltransferase palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)


Proteins

Protein ID name full name