(2R,3S)-3-(6-Amino-9H-purin-9-yl)nonan-2-ol (BioCAD00000173659)

blood

Metabolite Card

Formula: C14H23N5O (277.1903)
SMILES: CCCCCCC(C(C)O)N1C=NC2=C1N=CN=C2N

Synonyms [en]

EHNA; 9-(2-Hydroxy-3-nonyl)adenine, (S-(r*,r*))-isomer; 9-(2-hydroxy-3-nonyl)adenine, (S-(R*,S*))-isomer; 9-(2-hydroxy-3-nonyl)adenine monohycrochloride; 3-(6-aminopurin-9-yl)nonan-2-ol; 9-(2-hydroxy-3-nonyl)adenine, (R-(R*,R*))-isomer

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(2R,3S)-3-(6-Amino-9H-purin-9-yl)nonan-2-ol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000173659). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

(2R,3S)-EHNA is eHNA of absolute configuration 2R,3S. Selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 mM). Also a potent inhibitor of adenosine deaminase. It has a role as an EC 3.5.4.4 (adenosine deaminase) inhibitor and an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor. It is a conjugate base of a (2R,3S)-EHNA(1+). It is an enantiomer of a (2S,3R)-EHNA.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 51350-19-7
  • CAS Registry Number: 58337-38-5
  • CAS Registry Number: 59262-86-1
  • CAS Registry Number: 79813-68-6
  • PubChem: 149784
  • PubChem: 3206
  • ChEBI: ChEBI:63058
  • HMDB: HMDB0242539
  • BioCyc: EHNA
  • NCBI MeSH: 9-(2-hydroxy-3-nonyl)adenine
  • Wikipedia: EHNA
  • Metlin: METLIN_85107

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:META_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:META_PWY66-409 superpathway of purine nucleotide salvage
BioCyc:META_PWY-6609 adenine and adenosine salvage III
BioCyc:HUMAN_PWY66-409 superpathway of purine nucleotide salvage
BioCyc:META_PWY0-1296 purine ribonucleosides degradation
BioCyc:META_PWY-7528 L-methionine salvage cycle I (bacteria and plants)
BioCyc:META_PWY-7270 L-methionine salvage cycle II (plants)
BioCyc:HUMAN_SALVADEHYPOX-PWY adenosine nucleotides degradation
BioCyc:HUMAN_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate
BioCyc:META_PWY-6754 S-methyl-5'-thioadenosine degradation I
BioCyc:HUMAN_PWY-6353 purine nucleotides degradation
BioCyc:HUMAN_PWY-6609 adenine and adenosine salvage III
BioCyc:META_PWY-6353 purine nucleotides degradation II (aerobic)
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