EC: 5.4.2.8

phosphomannomutase (alpha-D-mannose 1,6-phosphomutase)

enzyme lambda metabolic reaction experiment
uniprot:P26276 [Mg2+]

D_Mannose_1_phosphate -> D_Mannose_6_phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM MOPS, 10 µM Glucose 1,6-diphosphate, 1 mM NADP, 1 U/ml Glucose 6-phosphate dehydrogenase, 1 U/ml Phosphoglucose isomerase
PH: 7.3
Temperature: 36
uniprot:P26276 [Ca2+]

D_Mannose_1_phosphate -> D_Mannose_6_phosphate		 (( (( (E * kcat) ) * M) ) / (( (Km * (1 + (I / Ki))) ) + M)) buffer: 50 mM MOPS, 10 µM Glucose 1,6-diphosphate, 1 mM NADP, 1 U/ml Glucose 6-phosphate dehydrogenase, 1 U/ml Phosphoglucose isomerase
PH: 7.3
Temperature: 36
uniprot:P26276 [Mg2+]

D_Mannose_1_phosphate -> D_Mannose_6_phosphate		 (( (( (E * kcat) ) * M) ) / (Km + M)) buffer: 50 mM MOPS, 10 µM Glucose 1,6-diphosphate, 1 mM NADP, 1 U/ml Glucose 6-phosphate dehydrogenase, 1 U/ml Phosphoglucose isomerase
PH: 7.3
Temperature: 36
uniprot:O15305 [alpha-D-Mannose 1,6-bisphosphate]

alpha_D_Mannose_1_phosphate -> alpha_D_Mannose_6_phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM K+ Hepes, 5 U/ml Glucose-6-phosphate dehydrogenase, 5 U/ml Phosphomannose isomerase, 5 U/ml Phosphoglucose isomerase
PH: 6.5
Temperature: 25
uniprot:Q92871 [alpha-D-Glucose 1,6-bisphosphate]

alpha_D_Glucose_1_phosphate -> alpha_D_Glucose_6_phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM K+ Hepes, 0.2 mM NADP, 5 U/ml Glucose-6-phosphate dehydrogenase
PH: 6.5
Temperature: 25
uniprot:O15305 [alpha-D-Glucose 1,6-bisphosphate]

alpha_D_Glucose_1_phosphate -> alpha_D_Glucose_6_phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM K+ Hepes, 0.2 mM NADP, 5 U/ml Glucose-6-phosphate dehydrogenase
PH: 6.5
Temperature: 25
uniprot:Q92871 [alpha-D-Mannose 1,6-bisphosphate]

alpha_D_Mannose_1_phosphate -> alpha_D_Mannose_6_phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM K+ Hepes, 5 U/ml Glucose-6-phosphate dehydrogenase, 5 U/ml Phosphomannose isomerase, 5 U/ml Phosphoglucose isomerase
PH: 6.5
Temperature: 25

Pathways

pathway id name
BioCyc:META_PWY-5659 GDP-mannose biosynthesis
BioCyc:YEAST_PWY3O-123 dolichyl phosphate D-mannose biosynthesis
BioCyc:VCHO_PWY-5659 GDP-mannose biosynthesis
BioCyc:ECOL316407_COLANSYN-PWY colanic acid building blocks biosynthesis
BioCyc:HUMAN_PWY-5659 GDP-mannose biosynthesis
BioCyc:META_PWY-7323 superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis
BioCyc:META_PWY-882 L-ascorbate biosynthesis I (L-galactose pathway)
BioCyc:ECO_PWY-5659 GDP-mannose biosynthesis
BioCyc:MOUSE_COLANSYN-PWY colanic acid building blocks biosynthesis
BioCyc:META_COLANSYN-PWY colanic acid building blocks biosynthesis
BioCyc:ECO_COLANSYN-PWY colanic acid building blocks biosynthesis
BioCyc:YEAST_PWY-5659 GDP-mannose biosynthesis
BioCyc:ECOO157_COLANSYN-PWY colanic acid building blocks biosynthesis
BioCyc:MOUSE_PWY-5659 GDP-mannose biosynthesis
BioCyc:ARA_PWY-882 L-ascorbate biosynthesis I (L-galactose pathway)
BioCyc:ARA_PWY-5659 GDP-mannose biosynthesis
BioCyc:ECOO157_PWY-5659 GDP-mannose biosynthesis
BioCyc:MOUSE_MANGDPMET-PWY GDP-mannose metabolism
BioCyc:MOUSE_PWY-5657 GDP-mannose biosynthesis I
BioCyc:ECOL316407_PWY-5659 GDP-mannose biosynthesis
PathBank:SMP0000842 Mannose Metabolism
PathBank:SMP0000906 Amino Sugar and Nucleotide Sugar Metabolism II
PathBank:SMP0000967 Colanic Acid Building Blocks Biosynthesis
Plant Reactome:R-OSA-2883407 Carbohydrate metabolism
Plant Reactome:R-OSA-1119628 GDP-mannose metabolism
Plant Reactome:R-OSA-1119410 Ascorbate biosynthesis
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2867929 Cofactor biosyntheses
PlantCyc:ARA_PWY-5659 GDP-mannose biosynthesis
PlantCyc:ARA_PWY-882 L-ascorbate biosynthesis I (L-galactose pathway)
PlantCyc:PLANT_PWY-882 L-ascorbate biosynthesis I (L-galactose pathway)
PlantCyc:PLANT_PWY-5659 GDP-mannose biosynthesis
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-DME-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-SCE-597592 Post-translational protein modification
Reactome:R-SCE-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-SPO-446203 Asparagine N-linked glycosylation
Reactome:R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-DME-446205 Synthesis of GDP-mannose
Reactome:R-SCE-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-SCE-446205 Synthesis of GDP-mannose
Reactome:R-DME-392499 Metabolism of proteins
Reactome:R-SPO-392499 Metabolism of proteins
Reactome:R-SPO-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-SPO-446205 Synthesis of GDP-mannose
Reactome:R-DME-446203 Asparagine N-linked glycosylation
Reactome:R-SCE-392499 Metabolism of proteins
Reactome:R-SCE-446203 Asparagine N-linked glycosylation
Reactome:R-SPO-597592 Post-translational protein modification
Reactome:R-SPO-446219 Synthesis of substrates in N-glycan biosythesis
WikiPathways:WP4521 Glycosylation and related congenital defects
PathBank:SMP0000064 Fructose and Mannose Degradation
PathBank:SMP0002331 Amino Sugar and Nucleotide Sugar Metabolism
PathBank:SMP0087197 Fructose and Mannose Degradation
PathBank:SMP0000725 Fructose Intolerance, Hereditary
PathBank:SMP0012444 Mannose Metabolism
PathBank:SMP0000561 Fructosuria
PathBank:SMP0002315 Mannose Metabolism