EC: 4.2.1.10

3-dehydroquinate dehydratase (3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming))

enzyme lambda metabolic reaction experiment
uniprot:P24670 [3-dehydroquinate dehydratase(Enzyme) wildtype]

3_Dehydroquinate -> 3_Dehydroshikimate + H2O
(( (( (kcat * E) ) * A) ) / (Km + A)) buffer: 50 mM Potassium phosphate
PH: 7
Temperature: 25
uniprot:P15474 [3-dehydroquinate dehydratase(Enzyme) wildtype]

3_Dehydroquinate -> H2O + 3_Dehydroshikimate
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris-HCl
PH: 8
Temperature: 30
uniprot:P15474 [3-dehydroquinate dehydratase(Enzyme) mutant R23K]

3_Dehydroquinate -> 3_Dehydroshikimate + H2O
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris acetate
PH: 8
Temperature: 25
uniprot:P15474 [3-dehydroquinate dehydratase(Enzyme) mutant R23Q]

3_Dehydroquinate -> 3_Dehydroshikimate + H2O
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris acetate
PH: 8
Temperature: 25
uniprot:P15474 [3-dehydroquinate dehydratase(Enzyme) wildtype]

3_Dehydroquinate -> H2O + 3_Dehydroshikimate
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris acetate
PH: 8
Temperature: 25
uniprot:P15474 [3-dehydroquinate dehydratase(Enzyme) mutant R23A]

3_Dehydroquinate -> 3_Dehydroshikimate + H2O
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 50 mM Tris acetate
PH: 8
Temperature: 25

Pathways

pathway id name
BioCyc:META_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:META_PWY-6954 superpathway of aromatic compound degradation via 2-hydroxypentadienoate
BioCyc:META_PWY-6165 chorismate biosynthesis II (archaea)
BioCyc:META_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ECO_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:YEAST_PWY-6164 3-dehydroquinate biosynthesis
BioCyc:YEAST_ARO-YEAST-PWY chorismate biosynthesis
BioCyc:VCHO_ARO-PWY chorismate biosynthesis I
BioCyc:MTBH37RV_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:MTBH37RV_ARO-PWY chorismate biosynthesis I
BioCyc:ECOO157_PWY-6630 superpathway of tyrosine biosynthesis
BioCyc:ECOL199310_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOL199310_ARO-PWY chorismate biosynthesis I
BioCyc:ECOL199310_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:ECOL199310_PWY-6628 superpathway of phenylalanine biosynthesis
BioCyc:ANTHRA_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ANTHRA_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:BSUB_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOL316407_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:CORYNE_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:META_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:META_QUINATEDEG-PWY quinate degradation I
BioCyc:ECO_ARO-PWY chorismate biosynthesis I
BioCyc:ARA_PWY-6707 gallate biosynthesis
BioCyc:VCHO_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:VCHO_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:VCHO_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:HPY_ARO-PWY chorismate biosynthesis I
BioCyc:ECOO157_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:ECOO157_PWY-6629 superpathway of tryptophan biosynthesis
BioCyc:ANTHRA_ARO-PWY chorismate biosynthesis I
BioCyc:ANTHRA_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:AGRO_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:BSUB_ARO-PWY chorismate biosynthesis I
BioCyc:PCHR_PWY-6416 quinate degradation II
BioCyc:ECOL316407_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:ECOL316407_ARO-PWY chorismate biosynthesis I
BioCyc:PDIF272563_ARO-PWY chorismate biosynthesis I
BioCyc:PDIF272563_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:CORYNE_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:GCF_000013425_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:META_PWY-2504 superpathway of aromatic compound degradation via 3-oxoadipate
BioCyc:META_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:META_ARO-PWY chorismate biosynthesis I
BioCyc:META_PWY-6416 quinate degradation II
BioCyc:META_PWY-6164 3-dehydroquinate biosynthesis I
BioCyc:META_PWY-6707 gallate biosynthesis
BioCyc:ECO_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:YEAST_COMPLETE-ARO-YEAST-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
BioCyc:VCHO_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:MTBCDC1551_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOO157_ARO-PWY chorismate biosynthesis I
BioCyc:ECOO157_PWY-6628 superpathway of phenylalanine biosynthesis
BioCyc:ECOL199310_PWY-6629 superpathway of tryptophan biosynthesis
BioCyc:CAULO_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:AGRO_QUINATEDEG-PWY quinate degradation I
BioCyc:BSUB_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:PCHR_ARO-PWY chorismate biosynthesis I
BioCyc:PDIF272563_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:CORYNE_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:CORYNE_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:CORYNE_PWY-6416 quinate degradation II
BioCyc:GCF_000013425_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:META_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:META_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:ECO_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ARA_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:VCHO_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:VCHO_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:MTBH37RV_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:MTBH37RV_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:MTBCDC1551_ARO-PWY chorismate biosynthesis I
BioCyc:HPY_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOO157_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOL199310_PWY-6630 superpathway of tyrosine biosynthesis
BioCyc:ECOL199310_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:CAULO_ARO-PWY chorismate biosynthesis I
BioCyc:ANTHRA_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:AGRO_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:AGRO_ARO-PWY chorismate biosynthesis I
BioCyc:BSUB_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:PCHR_PWY-6164 3-dehydroquinate biosynthesis I
BioCyc:PCHR_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:ECOL316407_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
BioCyc:CAULONA1000_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:CAULONA1000_ARO-PWY chorismate biosynthesis
BioCyc:CORYNE_ARO-PWY chorismate biosynthesis I
BioCyc:CORYNE_PWY18HP-1 superpathway of aromatic compound degradation
BioCyc:CORYNE_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:GCF_000013425_PWY-6629 superpathway of L-tryptophan biosynthesis
BioCyc:GCF_000013425_ARO-PWY chorismate biosynthesis I
PathBank:SMP0000836 Chorismate Biosynthesis
PathBank:SMP0001001 Secondary Metabolites: Shikimate Pathway
PlantCyc:ARA_ARO-PWY chorismate biosynthesis I
PlantCyc:PLANT_PWY-6707 gallate biosynthesis
PlantCyc:PLANT_ARO-PWY chorismate biosynthesis I
PlantCyc:ARA_PWY-6707 gallate biosynthesis
PlantCyc:ARA_PWY-6163 chorismate biosynthesis from 3-dehydroquinate
Reactome:R-MTU-870392 Mycobacterium tuberculosis biological processes
Reactome:R-MTU-964903 Chorismate via Shikimate Pathway
PathBank:SMP0012009 Shikimate Pathway (Chorismate Biosynthesis)