superpathway of L-tryptophan biosynthesis
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.1.1.25 | shikimate dehydrogenase (NADP+) | shikimate:NADP+ 3-oxidoreductase | |
| 2.4.2.18 | anthranilate phosphoribosyltransferase | N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase | |
| 2.5.1.19 | 3-phosphoshikimate 1-carboxyvinyltransferase | phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase | |
| 2.7.1.71 | shikimate kinase | ATP:shikimate 3-phosphotransferase | |
| 4.1.1.48 | indole-3-glycerol-phosphate synthase | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(indol-3-yl)glycerol-3-phosphate-forming] | |
| 4.2.1.10 | 3-dehydroquinate dehydratase | 3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming) | |
| 4.2.1.20 | tryptophan synthase | L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming] | |
| 4.2.3.4 | 3-dehydroquinate synthase | 3-deoxy-D-arabino-hept-2-ulosonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming) | |
| 4.2.3.5 | chorismate synthase | 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming) | |
| 5.3.1.24 | phosphoribosylanthranilate isomerase | N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase |
Proteins
| Protein ID | name | full name |
|---|---|---|
| Q05615 | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase |
| Q2FXY1 | aroE | Shikimate dehydrogenase (NADP(+)) |
| Q2FY32 | aroK | Shikimate kinase |
| Q2FYG9 | aroC | Chorismate synthase |
| Q2FYH0 | aroB | 3-dehydroquinate synthase |
| Q2FYR3 | trpA | Tryptophan synthase alpha chain |
| Q2FYR4 | trpB | Tryptophan synthase beta chain |
| Q2FYR5 | trpF | N-(5'-phosphoribosyl)anthranilate isomerase |
| Q2FYR6 | trpC | Indole-3-glycerol phosphate synthase |
| Q2FYR7 | trpD | Anthranilate phosphoribosyltransferase |
| Q2G002 | aroD | 3-dehydroquinate dehydratase |