superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis

Metabolites

2-Oxoglutarate

Formula: C5H6O5 (146.0215226)

CAS ID: 328-50-7

3-(4-Hydroxyphenyl)pyruvate

Formula: C9H8O4 (180.0422568)

CAS ID: 156-39-8

Anthranilate

Formula: C7H7NO2 (137.0476762)

CAS ID: 118-92-3

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

NADH

Formula: C21H29N7O14P2 (665.1247674)

CAS ID: 58-68-4

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

NADPH

Formula: C21H30N7O17P3 (745.0911)

CAS ID: 2646-71-1

Phenylpyruvate

Formula: C9H8O3 (164.0473418)

CAS ID: 156-06-9



Enzyme

EC Number name full name note
1.1.1.25 shikimate dehydrogenase (NADP+) shikimate:NADP+ 3-oxidoreductase
2.4.2.18 anthranilate phosphoribosyltransferase N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase
2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase
2.7.1.71 shikimate kinase ATP:shikimate 3-phosphotransferase
4.1.1.48 indole-3-glycerol-phosphate synthase 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(indol-3-yl)glycerol-3-phosphate-forming]
4.2.1.10 3-dehydroquinate dehydratase 3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)
4.2.1.20 tryptophan synthase L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]
4.2.3.4 3-dehydroquinate synthase 3-deoxy-D-arabino-hept-2-ulosonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming)
4.2.3.5 chorismate synthase 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)


Proteins

Protein ID name full name
B8GWN2 aroQ 3-dehydroquinate dehydratase
B8GWP8 trpD Anthranilate phosphoribosyltransferase
B8GWP9 trpC Indole-3-glycerol phosphate synthase
B8GWW0 aroE Shikimate dehydrogenase (NADP(+))
B8H331 aroK Shikimate kinase
B8H332 aroB 3-dehydroquinate synthase
B8H3W7 aroC Chorismate synthase
B8H661 trpA Tryptophan synthase alpha chain
B8H6A8 aroA 3-phosphoshikimate 1-carboxyvinyltransferase