EC: 2.3.1.85

fatty-acid synthase system (acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing))

enzyme lambda metabolic reaction experiment
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 14 H+ + Acetyl_CoA -> 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Palmitate + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM phosphate, 5 mM beta-mercaptoethanol, 3 mM EDTA
PH: 6.8
Temperature: 38
- [fatty-acid synthase(Enzyme) wildtype]

14 H+ + Acetyl_CoA + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> Palmitate + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (V * A) ) / (( (Ka * (1 + (I / Kis))) ) + A)) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

14 H+ + Acetyl_CoA + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Palmitate + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (V * A) ) * B) ) / (( (( (Ka * B) ) + (Kb * A)) ) + (A * B))) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

14 H+ + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA -> 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Palmitate + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (( (V * A) ) * B) ) / (( (( (Ka * B) ) + (Kb * A)) ) + (A * B))) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 14 H+ + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA -> 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Palmitate + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (V * A) ) / (( (Ka * (1 + (I / Kis))) ) + A)) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 14 H+ -> 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Palmitate + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (V * A) ) / (( (Ka * (1 + (I / Kis))) ) + A)) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

Acetyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 14 H+ + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Palmitate + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (V * A) ) / (Ka + (A * (1 + (I / Kii))))) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 14 H+ -> 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Palmitate		 (( (V * A) ) / (Ka + (A * (1 + (I / Kii))))) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
- [fatty-acid synthase(Enzyme) wildtype]

Acetyl_CoA + 14 H+ + 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> 14 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + 7 n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Palmitate + 8 n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (V * A) ) / (Ka + (A * (1 + (I / Kii))))) buffer: 0.2 M Phosphate, 1 mM Dithiothreitol, 3 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699A HFAS]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699Q HFAS]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype HFAS]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA -> Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype HFAS]

Acetyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699A HFAS]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699A HFAS]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA -> Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699Q HFAS]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA -> n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) mutant K1699Q HFAS]

Acetyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Long_chain_fatty_acid		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype HFAS]

Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Long_chain_fatty_acid		 (( (( (E * kcat) ) * C) ) / (Km + C)) buffer: 0.1 M KH2PO4, 1 mM EDTA
PH: 7
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + H+ -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S3) ) / (Km + S3)) buffer: 0.075 M Potassium phosphate, 5 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype]

Acetyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid		 (( (Vmax * S1) ) / (Km + S1)) buffer: 0.075 M Potassium phosphate, 5 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype]

Acetyl_CoA + H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Long_chain_fatty_acid		 (( (Vmax * S2) ) / (Km + S2)) buffer: 0.075 M Potassium phosphate, 5 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P49327 [fatty-acid synthase(Enzyme) wildtype]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Butanoyl_CoA + H+ -> n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S1) ) / (Km + S1)) buffer: 0.075 M Potassium phosphate, 5 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + H+ -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S3) ) / (Km + S3)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + H+ -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid		 (( (Vmax * S3) ) / (Km + S3)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Acetyl_CoA + H+ -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (Vmax * S2) ) / (Km + S2)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Acetyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ -> Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ + Propanoyl_CoA -> Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Butanoyl_CoA + H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Long_chain_fatty_acid		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Octanoyl_CoA -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + Hexanoyl_CoA -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12276 [fatty-acid synthase(Enzyme) wildtype]

Acetyl_CoA + H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2		 (( (Vmax * S2) ) / (Km + S2)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

Propanoyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

Butanoyl_CoA + H+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

H+ + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + Octanoyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A + Long_chain_fatty_acid		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25
uniprot:P12785 [fatty-acid synthase(Enzyme) wildtype]

2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADPH + H+ + Hexanoyl_CoA + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_Malonyl_CoA -> 2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_2n_NADP+ + n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_n_CO2 + Long_chain_fatty_acid + n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_n+1_Coenzyme_A		 (( (Vmax * S1) ) / (Km + S1)) buffer: 60 mM Potassium phosphate, 4 mM Dithiothreitol
PH: 6.5
Temperature: 25

Pathways

pathway id name
Reactome:R-HSA-9029558 LXRs regulate gene expression linked to lipogenesis
Reactome:R-HSA-9024446 LXR-mediated signaling
Reactome:R-HSA-9824446 Viral Infection Pathways
Reactome:R-HSA-9918487 Dengue Virus Genome Translation and Replication
Reactome:R-HSA-9839923 Dengue Virus Infection
Reactome:R-HSA-9918481 Dengue Virus-Host Interactions
Reactome:R-HSA-75105 Fatty acyl-CoA biosynthesis
Reactome:R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-HSA-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-MMU-75105 Fatty acyl-CoA biosynthesis
Reactome:R-MMU-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-MMU-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-RNO-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-RNO-199220 Vitamin B5 (pantothenate) metabolism
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-2426168 Activation of gene expression by SREBF (SREBP)
Reactome:R-HSA-163765 ChREBP activates metabolic gene expression
Reactome:R-HSA-196854 Metabolism of vitamins and cofactors
Reactome:R-HSA-9006931 Signaling by Nuclear Receptors
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-196854 Metabolism of vitamins and cofactors
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-RNO-75105 Fatty acyl-CoA biosynthesis
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-8957322 Metabolism of steroids
Reactome:R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF)
Reactome:R-HSA-163685 Integration of energy metabolism
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-HSA-5663205 Infectious disease
WikiPathways:WP5220 Metabolic reprogramming in pancreatic cancer
PathBank:SMP0087257 Fatty Acid Biosynthesis
PathBank:SMP0000456 Fatty Acid Biosynthesis