EC: 1.17.1.4

xanthine dehydrogenase (xanthine:NAD+ oxidoreductase)

enzyme lambda metabolic reaction experiment
uniprot:P80457 [xanthine dehydrogenase(Enzyme) wildtype dithioerythritol treated]

NAD+ + H2O + Xanthine -> NADH + Urate + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 0.1 M Tris-HCl, 0.033 mM Methylene blue
PH: 8.1
Temperature: 25
uniprot:P80457 [xanthine dehydrogenase(Enzyme) wildtype dithioerythritol treated]

H2O + Xanthine + NAD+ -> Urate + NADH + H+		 (( (Vmax * S) ) / (Km + S)) buffer: 0.1 M Tris-HCl, 0.033 mM Methylene blue
PH: 8.1
Temperature: 25

Pathways

pathway id name
BioCyc:HUMAN_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:META_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:META_PWY-5044 purine nucleotides degradation I (plants)
BioCyc:META_PWY-5695 inosine 5'-phosphate degradation
BioCyc:META_PWY-6607 guanosine nucleotides degradation I
BioCyc:MOUSE_URSIN-PWY ureide biosynthesis
BioCyc:BSUB_PWY-6608 guanosine nucleotides degradation III
BioCyc:BSUB_URSIN-PWY ureide biosynthesis
BioCyc:ECOL316407_PWY-6608 guanosine nucleotides degradation III
BioCyc:HUMAN_PWY-6875 retinoate biosynthesis II
BioCyc:META_PWY-6596 adenosine nucleotides degradation I
BioCyc:META_P165-PWY superpathway of purines degradation in plants
BioCyc:ARA_PWY-6596 adenosine nucleotides degradation I
BioCyc:MOUSE_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:BSUB_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:HUMAN_PWY-6608 guanosine nucleotides degradation
BioCyc:HUMAN_SALVADEHYPOX-PWY adenosine nucleotides degradation
BioCyc:META_PWY-6608 guanosine nucleotides degradation III
BioCyc:ECO_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:ARA_PWY-6606 guanosine nucleotides degradation II
BioCyc:ARA_PWY-6607 guanosine nucleotides degradation I
BioCyc:MOUSE_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation
BioCyc:MOUSE_SALVADEHYPOX-PWY adenosine nucleotides degradation II
BioCyc:HUMAN_PWY-6353 purine nucleotides degradation
BioCyc:META_PWY-6875 retinoate biosynthesis II
BioCyc:META_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:META_PWY-6595 superpathway of guanosine nucleotides degradation (plants)
BioCyc:META_PWY-6606 guanosine nucleotides degradation II
BioCyc:ECO_PWY-6608 guanosine nucleotides degradation III
BioCyc:MOUSE_PWY-6608 guanosine nucleotides degradation III
BioCyc:BSUB_PWY-6353 purine nucleotides degradation II (aerobic)
BioCyc:BSUB_PWY-5695 inosine 5'-phosphate degradation
BioCyc:ECOL316407_SALVADEHYPOX-PWY adenosine nucleotides degradation II
PathBank:SMP0002103 Adenosine Nucleotides Degradation
Plant Reactome:R-OSA-5655149 Nucleotide metabolism
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-1119407 ureide biogenesis
PlantCyc:ARA_P165-PWY superpathway of purines degradation in plants
PlantCyc:PLANT_P165-PWY superpathway of purines degradation in plants
PlantCyc:ARA_PWY-6596 adenosine nucleotides degradation I
PlantCyc:PLANT_PWY-6596 adenosine nucleotides degradation I
PlantCyc:PLANT_PWY-6607 guanosine nucleotides degradation I
PlantCyc:ARA_PWY-6606 guanosine nucleotides degradation II
PlantCyc:PLANT_PWY-6595 superpathway of guanosine nucleotides degradation (plants)
PlantCyc:PLANT_PWY-5044 purine nucleotides degradation I (plants)
PlantCyc:ARA_PWY-6607 guanosine nucleotides degradation I
PlantCyc:ARA_PWY-5044 purine nucleotides degradation I (plants)
PlantCyc:ARA_PWY-6595 superpathway of guanosine nucleotides degradation (plants)
PlantCyc:PLANT_PWY-6606 guanosine nucleotides degradation II
Reactome:R-RNO-9748784 Drug ADME
Reactome:R-DDI-9748787 Azathioprine ADME
Reactome:R-DME-9748787 Azathioprine ADME
Reactome:R-HSA-9748787 Azathioprine ADME
Reactome:R-MMU-9748784 Drug ADME
Reactome:R-RNO-9748787 Azathioprine ADME
Reactome:R-DDI-9748784 Drug ADME
Reactome:R-DME-9748784 Drug ADME
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-MMU-9748787 Azathioprine ADME
Reactome:R-DDI-74259 Purine catabolism
Reactome:R-DDI-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-GGA-1660598 Metabolism
Reactome:R-HSA-8851680 Butyrophilin (BTN) family interactions
Reactome:R-MMU-168256 Immune System
Reactome:R-MMU-1430728 Metabolism
Reactome:R-RNO-1280218 Adaptive Immune System
Reactome:R-DDI-15869 Nucleotide metabolism
Reactome:R-DDI-8956319 Nucleotide catabolism
Reactome:R-DDI-196854 Metabolism of vitamins and cofactors
Reactome:R-DME-1430728 Metabolism
Reactome:R-DME-196849 Metabolism of water-soluble vitamins and cofactors
Reactome:R-GGA-419470 Nucleotide metabolism
Reactome:R-HSA-74259 Purine catabolism
Reactome:R-MMU-8851680 Butyrophilin (BTN) family interactions
Reactome:R-MMU-74259 Purine catabolism
Reactome:R-RNO-74259 Purine catabolism
Reactome:R-RNO-168256 Immune System
Reactome:R-DME-15869 Nucleotide metabolism
Reactome:R-DME-8956319 Nucleotide catabolism
Reactome:R-DME-964975 Vitamin B6 activation to pyridoxal phosphate
Reactome:R-HSA-168256 Immune System
Reactome:R-MMU-1280218 Adaptive Immune System
Reactome:R-RNO-1430728 Metabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-964975 Vitamin B6 activation to pyridoxal phosphate
Reactome:R-DME-74259 Purine catabolism
Reactome:R-DME-196854 Metabolism of vitamins and cofactors
Reactome:R-GGA-419474 Purine metabolism
Reactome:R-GGA-421178 Urate synthesis
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-HSA-8956319 Nucleotide catabolism
Reactome:R-HSA-1280218 Adaptive Immune System
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-MMU-8956319 Nucleotide catabolism
Reactome:R-RNO-15869 Nucleotide metabolism
Reactome:R-RNO-8956319 Nucleotide catabolism
Reactome:R-RNO-8851680 Butyrophilin (BTN) family interactions
WikiPathways:WP4792 Purine metabolism
WikiPathways:WP5355 Metabolic Epileptic Disorders
WikiPathways:WP4224 Purine metabolism and related disorders
WikiPathways:WP4507 Molybdenum cofactor (Moco) biosynthesis
PathBank:SMP0120448 Adenosine Deaminase Deficiency
PathBank:SMP0120452 AICA-Ribosiduria
PathBank:SMP0120508 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0120532 Molybdenum Cofactor Deficiency
PathBank:SMP0120536 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0120577 Xanthinuria Type I
PathBank:SMP0120601 Mitochondrial DNA Depletion Syndrome
PathBank:SMP0000028 Caffeine Metabolism
PathBank:SMP0000167 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0000512 Xanthinuria Type I
PathBank:SMP0000536 Mitochondrial DNA Depletion Syndrome-3
PathBank:SMP0000609 Mercaptopurine Metabolism Pathway
PathBank:SMP0063475 Caffeine Metabolism
PathBank:SMP0063604 Caffeine Metabolism
PathBank:SMP0063668 Purine Metabolism
PathBank:SMP0120600 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0000050 Purine Metabolism
PathBank:SMP0000144 Adenosine Deaminase Deficiency
PathBank:SMP0000203 Molybdenum Cofactor Deficiency
PathBank:SMP0000428 Mercaptopurine Action Pathway
PathBank:SMP0000535 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0120449 Adenylosuccinate Lyase Deficiency
PathBank:SMP0120489 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0120497 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0120578 Xanthinuria Type II
PathBank:SMP0120602 Myoadenylate Deaminase Deficiency
PathBank:SMP0000365 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0000210 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0000430 Thioguanine Action Pathway
PathBank:SMP0000513 Xanthinuria Type II
PathBank:SMP0000537 Myoadenylate Deaminase Deficiency
PathBank:SMP0000650 Doxorubicin Metabolism Pathway
PathBank:SMP0012052 AMP Degradation (Hypoxanthine Route)
PathBank:SMP0000364 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0000168 AICA-Ribosiduria
PathBank:SMP0000427 Azathioprine Action Pathway
PathBank:SMP0063777 Nitric Oxide Signaling Pathway