Pathways Knowlegdes

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Pathway DOIs Note
Metabolism

Accession ID: Reactome:R-BTA-1430728		 -
Metabolism

Accession ID: Reactome:R-CFA-1430728		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-CFA-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Aflatoxin activation and detoxification

Accession ID: Reactome:R-GGA-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Biological oxidations

Accession ID: Reactome:R-HSA-211859		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-HSA-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Metabolism

Accession ID: Reactome:R-MMU-1430728		 -
Biological oxidations

Accession ID: Reactome:R-MMU-211859		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-MMU-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Aflatoxin activation and detoxification

Accession ID: Reactome:R-XTR-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Biological oxidations

Accession ID: Reactome:R-BTA-211859		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-BTA-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Biological oxidations

Accession ID: Reactome:R-RNO-211859		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-RNO-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Metabolism

Accession ID: Reactome:R-SSC-1430728		 -
Biological oxidations

Accession ID: Reactome:R-SSC-211859		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-SSC-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.
Biological oxidations

Accession ID: Reactome:R-CFA-211859		 -
Metabolism

Accession ID: Reactome:R-DRE-1430728		 -
Aflatoxin activation and detoxification

Accession ID: Reactome:R-DRE-5423646
  • 10.1016/s0027-5107(97)00289-3
  • 10.1080/03602530802563850
  • 10.1093/mutage/17.6.471
  • 10.3892/ol.2013.1169
 Hamid AS, Tesfamariam IG, Zhang Y, Zhang ZG. Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention. Oncol Lett. 2013 Apr;5(4):1087–92. PMID: 23599745; PMCID: PMC3629261.; Wu Q, Jezkova A, Yuan Z, Pavlikova L, Dohnal V, Kuca K. Biological degradation of aflatoxins. Drug Metab Rev. 2009;41(1):1–7. doi: 10.1080/03602530802563850. PMID: 19514968.; Wild CP, Turner PC. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis. 2002 Nov;17(6):471–81. doi: 10.1093/mutage/17.6.471. PMID: 12435844.; Guengerich FP, Johnson WW, Shimada T, Ueng Y, Yamazaki H, Langouët S. Activation and detoxication of aflatoxin B1. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998 Jun;402(1-2):121–8. doi: 10.1016/s0027-5107(97)00289-3.