cholesterol biosynthesis II (via 24,25-dihydrolanosterol)

Metabolites

(S)-2,3-Epoxysqualene

Formula: C30H50O (426.386145)

CAS ID: 54910-48-4

24,25-Dihydrolanosterol

Formula: C30H52O (428.4017942)

CAS ID: 79-62-9

4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol

Formula: C29H50O (414.386145)

CAS ID: 7240-15-5

4alpha-Methylcholesta-8-en-3beta-ol

Formula: C28H48O (400.37049579999996)

CAS ID: 5241-22-5

5alpha-Cholest-8-en-3beta-ol

Formula: C27H46O (386.3548466)

CAS ID: 566-97-2

7-Dehydrocholesterol

Formula: C27H44O (384.3391974)

CAS ID: 434-16-2

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Lanosterol

Formula: C30H50O (426.386145)

CAS ID: 79-63-0

Lathosterol

Formula: C27H46O (386.3548466)

CAS ID: 80-99-9

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Selenite

Formula: SeO3 (127.901266)

CAS ID: 14124-67-5

Squalene

Formula: C30H50 (410.39123)

CAS ID: 111-02-4

4,4-dimethyl-14alpha-formyl-5alpha-cholest-8-en-3beta-ol

Formula: C30H50O2 (442.38106)

CAS ID: 59200-40-7

4,4-dimethyl-14alpha-hydroxymethyl-5alpha-cholest-8-en-3beta-ol

Formula: C30H52O2 (444.3967092)

CAS ID: 59200-39-4

4,4-dimethyl-5alpha-cholesta-8,14-dien-3beta-ol

Formula: C29H48O (412.37049579999996)

CAS ID: 19456-83-8

4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol

Formula: C29H48O2 (428.36541079999995)

CAS ID:

4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol

Formula: C29H50O2 (430.38106)

CAS ID:

4α-methyl-5α-cholesta-8-en-3-one

Formula: C28H46O (398.3548466)

CAS ID:

5alpha-cholest-8-en-3-one

Formula: C27H44O (384.3391974)

CAS ID:

formate

Formula: CHO2 (44.997654600000004)

CAS ID: 71-47-6

tellurite

Formula: O3Te (177.890974)

CAS ID: 15852-22-9

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) 3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase 3beta-hydroxysteroid:NADP+ 3-oxidoreductase
1.1.1.62 17beta-estradiol 17-dehydrogenase 17beta-estradiol:NAD(P)+ 17-oxidoreductase
1.14.14.154 sterol 14alpha-demethylase sterol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
1.14.14.17 squalene monooxygenase squalene,NADPH-hemoprotein:oxygen oxidoreductase (2,3-epoxidizing
1.14.18.9 4alpha-methylsterol monooxygenase 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,ferrocytochrome-b5:oxygen oxidoreductase (C4alpha-methyl-hydroxylating)
1.14.19.20 DELTA7-sterol 5(6)-desaturase DELTA7-sterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating
1.3.1.21 7-dehydrocholesterol reductase cholesterol:NADP+ DELTA7-oxidoreductase
1.3.1.70 DELTA14-sterol reductase 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ DELTA14-oxidoreductase
1.3.1.72 DELTA24-sterol reductase sterol:NADP+ DELTA24-oxidoreductase
2.5.1.21 squalene synthase (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase
3.3.2.11 cholesterol-5,6-oxide hydrolase 5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase
5.3.3.5 cholestenol DELTA-isomerase DELTA7-Cholestenol DELTA7-DELTA8-isomerase
5.4.99.7 Lanosterol synthase (S)-2,3-Epoxysqualene mutase (cyclizing, lanosterol-forming)


Proteins

Protein ID name full name