Cell surface interactions at the vascular wall

Weber C, Fraemohs L, Dejana E. The role of junctional adhesion molecules in vascular inflammation. Nat Rev Immunol. 2007 Jun;7(6):467–77. doi: 10.1038/nri2096. PMID: 17525755.; Schober A, Weber C. Mechanisms of monocyte recruitment in vascular repair after injury. Antioxid Redox Signal. 2005 Sep;7(9-10):1249–57. doi: 10.1089/ars.2005.7.1249. PMID: 16115029.; da Costa Martins P, van den Berk N, Ulfman LH, Koenderman L, Hordijk PL, Zwaginga JJ. Platelet-monocyte complexes support monocyte adhesion to endothelium by enhancing secondary tethering and cluster formation. Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):193–9. doi: 10.1161/01.atv.0000106320.40933.e5. PMID: 14615387.; Jackson SP, Mistry N, Yuan Y. Platelets and the injured vessel wall-- 'rolling into action': focus on glycoprotein Ib/V/IX and the platelet cytoskeleton. Trends Cardiovasc Med. 2000 Jul;10(5):192–7. doi: 10.1016/s1050-1738(00)00062-1. PMID: 11282294.; Becker BF, Heindl B, Kupatt C, Zahler S. Endothelial function and hemostasis. Clinical Research in Cardiology. 2000 Mar;89(3):160–7. doi: 10.1007/pl00007320.; Furie B, Furie BC. The Molecular Basis of Platelet and Endothelial Cell Interaction with Neutrophils and Monocytes: Role of P-Selectin and the P-Selectin Ligand, PSGL-1. Thromb Haemost. 1995;74(01):224–7. doi: 10.1055/s-0038-1642681.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
3.1.3.36 phosphoinositide 5-phosphatase phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase
3.1.3.48 protein-tyrosine-phosphatase protein-tyrosine-phosphate phosphohydrolase
3.1.3.56 inositol-polyphosphate 5-phosphatase 1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase
3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase
3.1.4.11 phosphoinositide phospholipase C 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
3.4.21.5 thrombin
3.4.21.69 Protein C (activated)
3.4.24.7 interstitial collagenase
5.2.1.8 peptidylprolyl isomerase Peptidylproline cis-trans-isomerase
5.3.2.1 phenylpyruvate tautomerase phenylpyruvate keto---enol-isomerase
5.3.3.12 L-dopachrome isomerase L-dopachrome keto-enol isomerase


Proteins

Protein ID name full name