Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.

Metabolites

(25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA

Formula: C48H80N7O20P3S (1199.439147)

CAS ID:

3alpha,7alpha-Dihydroxy-5beta-cholestane

Formula: C27H48O2 (404.36541079999995)

CAS ID: 3862-26-8

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al

Formula: C27H46O4 (434.3395916)

CAS ID: 3836-01-9

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane

Formula: C27H48O3 (420.36032579999994)

CAS ID: 547-96-6

3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate

Formula: C27H46O5 (450.3345066)

CAS ID: 547-98-8

3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane

Formula: C27H48O4 (436.3552408)

CAS ID: 862-53-3

4-Cholesten-7alpha,12alpha-diol-3-one

Formula: C27H44O3 (416.3290274)

CAS ID: 1254-03-1

7alpha-Hydroxycholest-4-en-3-one

Formula: C27H44O2 (400.3341124)

CAS ID: 3862-25-7

7alpha-Hydroxycholesterol

Formula: C27H46O2 (402.34976159999997)

CAS ID: 566-26-7

7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one

Formula: C27H46O3 (418.34467659999996)

CAS ID: 547-97-7

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

3alpha,7alpha-Dihydroxycoprostanic acid

Formula: C27H46O4 (434.3395916)

CAS ID: 17974-66-2

3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA

Formula: C48H78N7O20P3S (1197.4234978)

CAS ID:

cholate

Formula: C24H39O5 (407.2797344)

CAS ID: 298-43-1

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note


Proteins

Protein ID name full name