KEGG:R00311

multi-step reaction

protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)

Heme[C34H32FeN4O4] + 3 [Reduced NADPH---hemoprotein reductase][] + 3 Oxygen[O2] = Biliverdin[C33H34N4O6] + CO[CO] + Fe2+[Fe] + 3 [Oxidized NADPH---hemoprotein reductase][] + 3 H2O[H2O]

DB Links

Alias

Metabolites

Substrates
metabolite compartment Structure
Heme

Formula: C34H32FeN4O4 		Cytoplasm
[Reduced NADPH---hemoprotein reductase]

Formula: 		Cytoplasm
Oxygen

Formula: O2 		Cytoplasm
Products
metabolite compartment Structure
Biliverdin

Formula: C33H34N4O6		 Cytoplasm
CO

Formula: CO		 Cytoplasm
Fe2+

Formula: Fe		 Cytoplasm
[Oxidized NADPH---hemoprotein reductase]

Formula: 		Cytoplasm
H2O

Formula: H2O		 Cytoplasm