Pathways Knowlegdes
Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit
| Pathway | DOIs | Note |
|---|---|---|
| sesamin biosynthesis Accession ID: BioCyc:META_PWY-5469 |
|
Ono E, Nakai M, Fukui Y, Tomimori N, Fukuchi-Mizutani M, Saito M, Satake H, Tanaka T, Katsuta M, Umezawa T, Tanaka Y. Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin. Proc. Natl. Acad. Sci. U.S.A. 2006 Jun 27;103(26):10116–21. doi: 10.1073/pnas.0603865103.; Nakano D, Itoh C, Ishii F, Kawanishi H, Takaoka M, Kiso Y, Tsuruoka N, Tanaka T, Matsumura Y. Effects of Sesamin on Aortic Oxidative Stress and Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertensive Rats. Biological & Pharmaceutical Bulletin. 2003;26(12):1701–5. doi: 10.1248/bpb.26.1701.; IKEDA S, KAGAYA M, KOBAYASHI K, TOHYAMA T, KISO Y, HIGUCHI N, YAMASHITA K. Dietary Sesame Lignans Decrease Lipid Peroxidation in Rats Fed Docosahexaenoic Acid. Journal of Nutritional Science and Vitaminology, J Nutr Sci Vitaminol. 2003;49(4):270–6. doi: 10.3177/jnsv.49.270.; Nakai M, Harada M, Nakahara K, Akimoto K, Shibata H, Miki W, Kiso Y. Novel antioxidative metabolites in rat liver with ingested sesamin. J Agric Food Chem. 2003 Mar 12;51(6):1666–70. doi: 10.1021/jf0258961. PMID: 12617602.; Ikeda S, Tohyama T, Yamashita K. Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2'-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gamma-tocopherol. J Nutr. 2002 May;132(5):961–6. doi: 10.1093/jn/132.5.961. PMID: 11983822.; Utsunomiya T, Chavali SR, Zhong WW, Forse RA. Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor a in rats. The American Journal of Clinical Nutrition. 2000 Sep;72(3):804–8. doi: 10.1093/ajcn/72.3.804. |
| taxol biosynthesis Accession ID: BioCyc:META_PWY-5660 |
|
Long RM, Croteau R. Preliminary assessment of the C13-side chain 2'-hydroxylase involved in Taxol biosynthesis. Biochemical and Biophysical Research Communications. 2005 Dec;338(1):410–7. doi: 10.1016/j.bbrc.2005.08.119.; Chau M, Croteau R. Molecular cloning and characterization of a cytochrome P450 taxoid 2alpha-hydroxylase involved in Taxol biosynthesis. Arch Biochem Biophys. 2004 Jul 01;427(1):48–57. doi: 10.1016/j.abb.2004.04.016. PMID: 15178487.; Chau M, Jennewein S, Walker K, Croteau R. Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase. Chem Biol. 2004 May;11(5):663–72. doi: 10.1016/j.chembiol.2004.02.025. PMID: 15157877.; Jennewein S, Rithner CD, Williams RM, Croteau R. Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase. Arch Biochem Biophys. 2003 May 15;413(2):262–70. doi: 10.1016/s0003-9861(03)00090-0. PMID: 12729625.; Walker K, Fujisaki S, Long R, Croteau R. Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis. Proc Natl Acad Sci U S A. 2002 Oct 01;99(20):12715–20. PMID: 12232048; PMCID: PMC130526.; Walker K, Long R, Croteau R. The final acylation step in Taxol biosynthesis: Cloning of the taxoid C13-side-chain N -benzoyltransferase from Taxus. Proc. Natl. Acad. Sci. U.S.A. 2002 Jun 27;99(14):9166–71. doi: 10.1073/pnas.082115799.; Jennewein S, Rithner CD, Williams RM, Croteau RB. Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13595–600. PMID: 11707604; PMCID: PMC61086.; Walker K, Croteau R. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2a-O-benzoyltransferase cDNA fromTaxusand functional expression inEscherichia coli. Proc. Natl. Acad. Sci. U.S.A. 2000 Nov 28;97(25):13591–6. doi: 10.1073/pnas.250491997.; Wildung MR, Croteau R. A cDNA Clone for Taxadiene Synthase, the Diterpene Cyclase That Catalyzes the Committed Step of Taxol Biosynthesis. Journal of Biological Chemistry. 1996 Apr;271(16):9201–4. doi: 10.1074/jbc.271.16.9201. |
| zymosterol biosynthesis Accession ID: BioCyc:META_PWY-6074 |
|
Mo C, Valachovic M, Randall SK, Nickels JT, Bard M. Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9739–44. PMID: 12119386; PMCID: PMC124998.; Parks LW, Casey WM. Physiological implications of sterol biosynthesis in yeast. Annu Rev Microbiol. 1995;49():95–116. doi: 10.1146/annurev.mi.49.100195.000523. PMID: 8561481. |
| superpathway of cholesterol biosynthesis Accession ID: BioCyc:HUMAN_PWY66-5 |
- | |
| cholesterol biosynthesis I Accession ID: BioCyc:HUMAN_PWY66-341 |
- | |
| rosmarinic acid biosynthesis I Accession ID: BioCyc:META_PWY-5048 |
|
Vogelsang K, Schneider B, Petersen M. Production of rosmarinic acid and a new rosmarinic acid 3'-O-beta-D-glucoside in suspension cultures of the hornwort Anthoceros agrestis Paton. Planta. 2006 Jan;223(2):369–73. doi: 10.1007/s00425-005-0089-8. PMID: 16133208.; Kim KH, Janiak V, Petersen M. Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Mol Biol. 2004 Feb;54(3):311–23. doi: 10.1023/b:plan.0000036367.03056.b2. PMID: 15284489.; Petersen M. Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis. Planta. 2003 May;217(1):96–101. doi: 10.1007/s00425-002-0960-9. PMID: 12721853.; Petersen M, Simmonds MS. Rosmarinic acid. Phytochemistry. 2003 Jan;62(2):121–5. doi: 10.1016/s0031-9422(02)00513-7. PMID: 12482446.; Matsuno M, Nagatsu A, Ogihara Y, Ellis BE, Mizukami H. CYP98A6 from Lithospermum erythrorhizon encodes 4-coumaroyl-4'-hydroxyphenyllactic acid 3-hydroxylase involved in rosmarinic acid biosynthesis1. FEBS Letters. 2002 Mar 13;514(2-3):219–24. doi: 10.1016/s0014-5793(02)02368-2.; Ellis BE, Towers GH. Biogenesis of rosmarinic acid in Mentha. Biochem J. 1970 Jun;118(2):291–7. PMID: 5484678; PMCID: PMC1179116. |
| superpathway of rosmarinic acid biosynthesis Accession ID: BioCyc:META_PWY-5071 |
|
Kim KH, Janiak V, Petersen M. Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Mol Biol. 2004 Feb;54(3):311–23. doi: 10.1023/b:plan.0000036367.03056.b2. PMID: 15284489.; Petersen M. Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis. Planta. 2003 May;217(1):96–101. doi: 10.1007/s00425-002-0960-9. PMID: 12721853.; Petersen M, Simmonds MS. Rosmarinic acid. Phytochemistry. 2003 Jan;62(2):121–5. doi: 10.1016/s0031-9422(02)00513-7. PMID: 12482446.; Matsuno M, Nagatsu A, Ogihara Y, Ellis BE, Mizukami H. CYP98A6 from Lithospermum erythrorhizon encodes 4-coumaroyl-4'-hydroxyphenyllactic acid 3-hydroxylase involved in rosmarinic acid biosynthesis1. FEBS Letters. 2002 Mar 13;514(2-3):219–24. doi: 10.1016/s0014-5793(02)02368-2.; Ellis BE, Towers GH. Biogenesis of rosmarinic acid in Mentha. Biochem J. 1970 Jun;118(2):291–7. PMID: 5484678; PMCID: PMC1179116. |
| cholesterol biosynthesis III (via desmosterol) Accession ID: BioCyc:HUMAN_PWY66-4 |
- | |
| sesamin biosynthesis Accession ID: PlantCyc:PLANT_PWY-5469 |
|
Ono E, Nakai M, Fukui Y, Tomimori N, Fukuchi-Mizutani M, Saito M, Satake H, Tanaka T, Katsuta M, Umezawa T, Tanaka Y. Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin. Proc. Natl. Acad. Sci. U.S.A. 2006 Jun 27;103(26):10116–21. doi: 10.1073/pnas.0603865103.; Nakano D, Itoh C, Ishii F, Kawanishi H, Takaoka M, Kiso Y, Tsuruoka N, Tanaka T, Matsumura Y. Effects of Sesamin on Aortic Oxidative Stress and Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertensive Rats. Biological & Pharmaceutical Bulletin. 2003;26(12):1701–5. doi: 10.1248/bpb.26.1701.; IKEDA S, KAGAYA M, KOBAYASHI K, TOHYAMA T, KISO Y, HIGUCHI N, YAMASHITA K. Dietary Sesame Lignans Decrease Lipid Peroxidation in Rats Fed Docosahexaenoic Acid. Journal of Nutritional Science and Vitaminology, J Nutr Sci Vitaminol. 2003;49(4):270–6. doi: 10.3177/jnsv.49.270.; Nakai M, Harada M, Nakahara K, Akimoto K, Shibata H, Miki W, Kiso Y. Novel antioxidative metabolites in rat liver with ingested sesamin. J Agric Food Chem. 2003 Mar 12;51(6):1666–70. doi: 10.1021/jf0258961. PMID: 12617602.; Ikeda S, Tohyama T, Yamashita K. Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2'-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gamma-tocopherol. J Nutr. 2002 May;132(5):961–6. doi: 10.1093/jn/132.5.961. PMID: 11983822.; Utsunomiya T, Chavali SR, Zhong WW, Forse RA. Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor a in rats. The American Journal of Clinical Nutrition. 2000 Sep;72(3):804–8. doi: 10.1093/ajcn/72.3.804. |
| rosmarinic acid biosynthesis I Accession ID: PlantCyc:PLANT_PWY-5048 |
|
Vogelsang K, Schneider B, Petersen M. Production of rosmarinic acid and a new rosmarinic acid 3'-O-beta-D-glucoside in suspension cultures of the hornwort Anthoceros agrestis Paton. Planta. 2006 Jan;223(2):369–73. doi: 10.1007/s00425-005-0089-8. PMID: 16133208.; Kim KH, Janiak V, Petersen M. Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Mol Biol. 2004 Feb;54(3):311–23. doi: 10.1023/b:plan.0000036367.03056.b2. PMID: 15284489.; Petersen M. Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis. Planta. 2003 May;217(1):96–101. doi: 10.1007/s00425-002-0960-9. PMID: 12721853.; Petersen M, Simmonds MS. Rosmarinic acid. Phytochemistry. 2003 Jan;62(2):121–5. doi: 10.1016/s0031-9422(02)00513-7. PMID: 12482446.; Matsuno M, Nagatsu A, Ogihara Y, Ellis BE, Mizukami H. CYP98A6 from Lithospermum erythrorhizon encodes 4-coumaroyl-4'-hydroxyphenyllactic acid 3-hydroxylase involved in rosmarinic acid biosynthesis1. FEBS Letters. 2002 Mar 13;514(2-3):219–24. doi: 10.1016/s0014-5793(02)02368-2.; Ellis BE, Towers GH. Biogenesis of rosmarinic acid in Mentha. Biochem J. 1970 Jun;118(2):291–7. PMID: 5484678; PMCID: PMC1179116. |
| superpathway of rosmarinic acid biosynthesis Accession ID: PlantCyc:PLANT_PWY-5071 |
|
Kim KH, Janiak V, Petersen M. Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Plant Mol Biol. 2004 Feb;54(3):311–23. doi: 10.1023/b:plan.0000036367.03056.b2. PMID: 15284489.; Petersen M. Cinnamic acid 4-hydroxylase from cell cultures of the hornwort Anthoceros agrestis. Planta. 2003 May;217(1):96–101. doi: 10.1007/s00425-002-0960-9. PMID: 12721853.; Petersen M, Simmonds MS. Rosmarinic acid. Phytochemistry. 2003 Jan;62(2):121–5. doi: 10.1016/s0031-9422(02)00513-7. PMID: 12482446.; Matsuno M, Nagatsu A, Ogihara Y, Ellis BE, Mizukami H. CYP98A6 from Lithospermum erythrorhizon encodes 4-coumaroyl-4'-hydroxyphenyllactic acid 3-hydroxylase involved in rosmarinic acid biosynthesis1. FEBS Letters. 2002 Mar 13;514(2-3):219–24. doi: 10.1016/s0014-5793(02)02368-2.; Ellis BE, Towers GH. Biogenesis of rosmarinic acid in Mentha. Biochem J. 1970 Jun;118(2):291–7. PMID: 5484678; PMCID: PMC1179116. |