L-citrulline biosynthesis

Curis E, Nicolis I, Moinard C, Osowska S, Zerrouk N, Bénazeth S, Cynober L. Almost all about citrulline in mammals. Amino Acids. 2005 Nov;29(3):177–205. doi: 10.1007/s00726-005-0235-4. PMID: 16082501.

Metabolites

Boric acid

Formula: H3BO3 (62.017523800000006)

CAS ID: 10043-35-3

Dithiothreitol

Formula: C4H10O2S2 (154.01222)

CAS ID: 3483-12-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Mercaptoethanol

Formula: C2H6OS (78.0139346)

CAS ID: 60-24-2

Urea

Formula: CH4N2O (60.0323614)

CAS ID: 57-13-6

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

L-argininium(1+)

Formula: C6H15N4O2 (175.119495)

CAS ID: 17806-42-7

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

1-pyrroline-5-carboxylate

Formula: C5H6NO2 (112.03985159999999)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:

L-lysinium(1+)

Formula: C6H15N2O2 (147.113347)

CAS ID: 56-87-1

L-homoarginine(1+)

Formula: C7H17N4O2 (189.1351442)

CAS ID:



Enzyme

EC Number name full name note
1.2.1.41 glutamate-5-semialdehyde dehydrogenase L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)
1.5.5.2 proline dehydrogenase L-proline:quinone oxidoreductase
2.1.3.3 ornithine carbamoyltransferase carbamoyl-phosphate:L-ornithine carbamoyltransferase
2.6.1.13 ornithine aminotransferase L-ornithine:2-oxo-acid aminotransferase
2.7.2.11 glutamate 5-kinase ATP:L-glutamate 5-phosphotransferase
3.5.1.2 glutaminase L-glutamine amidohydrolase
3.5.3.1 arginase L-arginine amidinohydrolase


Proteins

Protein ID name full name