1-pyrroline-5-carboxylate (BioCAD00000472607)

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Metabolite Card

Formula: C5H6NO2 (112.0399)
SMILES: N1=CCCC1C([O-])=O

Synonyms [en]

1-pyrroline-5-carboxylate; pyrroline 5-carboxylate; 3,4-dihydro-2H-pyrrole-2-carboxylate; L-Δ1-pyrroline-5-carboxylate; (2S)-3,4-dihydro-2H-pyrrole-2-carboxylate; delta-1-pyrroline-5-carboxylate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

1-pyrroline-5-carboxylate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000472607). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A 1-pyrrolinecarboxylate resulting from the removal of the proton from the carboxy group of 1-pyrroline-5-carboxylic acid." []

Entity Information

DBLinks

Other DBLinks
  • PubChem: 11966181
  • ChEBI: ChEBI:15893
  • ChEBI: ChEBI:17388
  • KEGG: C04322
  • BioCyc: CPD-478
  • BioCyc: L-DELTA1-PYRROLINE_5-CARBOXYLATE
  • NCBI MeSH: delta-1-pyrroline-5-carboxylate

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:PYRROLINECARBREDUCT-RXN 1.5.1.2 L-DELTA1-PYRROLINE_5-CARBOXYLATE + NADH-P-OR-NOP + 2 PROTON --> PRO + NAD-P-OR-NOP
BioCyc:SPONTPRO-RXN PROTON + WATER + L-DELTA1-PYRROLINE_5-CARBOXYLATE<=>L-GLUTAMATE_GAMMA-SEMIALDEHYDE
BioCyc:PYRROLINECARBDEHYDROG-RXN 1-pyrroline-5-carboxylate dehydrogenase
BioCyc:RXN0-7008 1.5.5.2 Ubiquinones + PRO --> Ubiquinols + PROTON + L-DELTA1-PYRROLINE_5-CARBOXYLATE
BioCyc:RXN0-7005 L-DELTA1-PYRROLINE_5-CARBOXYLATE + 2 E- + 3 PROTON --> PRO
BioCyc:RXN-21556 1.5.8.- PRO + FAD --> L-DELTA1-PYRROLINE_5-CARBOXYLATE + FADH2
BioCyc:RXN-16089 6.3.2.- S-ADENOSYLMETHIONINE + L-DELTA1-PYRROLINE_5-CARBOXYLATE + ARG + 2 ATP --> CPD-17338 + ADENOSYL-HOMO-CYS + 2 AMP + 2 PPI + WATER + 2 PROTON
BioCyc:RXN-13396 1.14.20.7 ARG + 2-KETOGLUTARATE + OXYGEN-MOLECULE --> L-DELTA1-PYRROLINE_5-CARBOXYLATE + CPD0-1470 + SUC + CARBON-DIOXIDE + WATER + PROTON
BioCyc:RXN-14903 1.5.5.2 ETR-Quinones + PRO --> ETR-Quinols + PROTON + L-DELTA1-PYRROLINE_5-CARBOXYLATE
BioCyc:RXN-12535 1.14.11.- ethylene forming enzyme
BioCyc:RXN-8947 2.3.1.226 PROTON + L-DELTA1-PYRROLINE_5-CARBOXYLATE + MALONYL-COA + WATER --> CPD-9369 + CO-A + CARBON-DIOXIDE
BioCyc:RXN-18502 4.2.1.172 4-HYDROXY-L-PROLINE --> L-DELTA1-PYRROLINE_5-CARBOXYLATE + WATER + PROTON
BioCyc:RXN-12536 CPD-15413 --> PROTON + CPD0-1470 + L-DELTA1-PYRROLINE_5-CARBOXYLATE + WATER
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PROSYN-PWY proline biosynthesis
BioCyc:META_PWY-5004 superpathway of L-citrulline metabolism
BioCyc:META_ARG-PRO-PWY L-arginine degradation VI (arginase 2 pathway)
BioCyc:YEAST_CITRULBIO-PWY citrulline biosynthesis
BioCyc:ARA_CITRULBIO-PWY L-citrulline biosynthesis
BioCyc:ARA_PROSYN-PWY L-proline biosynthesis I
BioCyc:ARA_PROUT-PWY L-proline degradation
BioCyc:TRYPANO_ARG-PRO-PWY arginine degradation VI (arginase 2 pathway)
BioCyc:TRYPANO_ARGININE-DEG1-PWY arginine degradation VII
BioCyc:PLASMO_PROSYN-PWY proline biosynthesis I
BioCyc:MTBH37RV_PROUT-PWY L-proline degradation
BioCyc:MTBH37RV_PROSYN-PWY L-proline biosynthesis I
BioCyc:ECOO157_PWY-3341 proline biosynthesis III
BioCyc:ANTHRA_ARG-PRO-PWY L-arginine degradation VI (arginase 2 pathway)
BioCyc:ANTHRA_PWY-3341 L-proline biosynthesis III
BioCyc:AGRO_PROSYN-PWY L-proline biosynthesis I
BioCyc:AURANTIMONAS_PWY-3341 L-proline biosynthesis III
BioCyc:AURANTIMONAS_PROSYN-PWY L-proline biosynthesis I
BioCyc:BSUB_PROSYN-PWY L-proline biosynthesis I
BioCyc:BSUB_PWY-6344 L-ornithine degradation II (Stickland reaction)
View All Pathways