superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae)

Metabolites

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen sulfide

Formula: H2S (33.9877212)

CAS ID: 7783-06-4

Hydroxylamine

Formula: NH3O (33.0214628)

CAS ID: 7803-49-8

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Phenylhydrazine

Formula: C6H8N2 (108.06874479999999)

CAS ID: 100-63-0

Semicarbazide

Formula: CH5N3O (75.04326)

CAS ID: 57-56-7

Sulfate

Formula: H2SO4 (97.9673812)

CAS ID: 7664-93-9

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

acetate

Formula: C2H3O2 (59.0133038)

CAS ID: 71-50-1

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

sulfite

Formula: O3S (79.956817)

CAS ID: 14265-45-3

siroheme(8-)

Formula: C42H36FeN4O16 (908.1475605999999)

CAS ID: 52553-42-1

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.8.1.2 assimilatory sulfite reductase (NADPH) hydrogen-sulfide:NADP+ oxidoreductase
1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin) adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)
2.3.1.31 homoserine O-acetyltransferase acetyl-CoA:L-homoserine O-acetyltransferase
2.5.1.47 cysteine synthase O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
2.5.1.48 cystathionine gamma-synthase O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase
2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase
2.7.1.25 adenylyl-sulfate kinase ATP:adenylyl-sulfate 3'-phosphotransferase
2.7.7.4 sulfate adenylyltransferase ATP:sulfate adenylyltransferase
4.2.1.22 cystathionine beta-synthase L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)
4.4.1.1 cystathionine gamma-lyase L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
4.4.1.13 cysteine-S-conjugate beta-lyase L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)


Proteins

Protein ID name full name
P06106 MET17 Homocysteine/cysteine synthase
P08465 MET2 Homoserine O-acetyltransferase
P08536 MET3 Sulfate adenylyltransferase
P18408 MET16 Phosphoadenosine phosphosulfate reductase
P31373 CYS3 Cystathionine gamma-lyase
P32582 CYS4 Cystathionine beta-synthase
P39692 MET10 Sulfite reductase [NADPH] flavoprotein component
P47164 STR2 Cystathionine gamma-synthase
P53101 STR3 Cystathionine beta-lyase
Q02196 MET14 Adenylyl-sulfate kinase