Ergosterol biosynthesis
Acimovic J, Rozman D. Steroidal triterpenes of cholesterol synthesis. Molecules. 2013 Apr 04;18(4):4002–17. PMID: 23558541; PMCID: PMC6269928.
Metabolites
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Formula: C29H46O (410.3548466)
CAS ID: 64284-64-6
4,4-dimethyl-14alpha-formyl-5alpha-cholesta-8,24-dien-3beta-ol
Formula: C30H48O2 (440.36541079999995)
CAS ID: 79294-83-0
4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol
Formula: C29H46O3 (442.34467659999996)
CAS ID: 32468-21-6
4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol
Formula: C29H46O2 (426.34976159999997)
CAS ID: 1028833-06-8
4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol
Formula: C29H48O2 (428.36541079999995)
CAS ID: 616897-75-7
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.14.18.- | |||
| 1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase | 3beta-hydroxysteroid:NADP+ 3-oxidoreductase | |
| 1.14.14.154 | sterol 14alpha-demethylase | sterol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P10614 | ERG11 | Lanosterol 14-alpha demethylase CYP51 |
| P53045 | ERG25 | C-4 methylsterol oxidase ERG25 |
| Q12452 | ERG27 | 3-keto-steroid reductase ERG27 |