(R)-5-Phosphomevalonate (BioCAD00000000850)
Metabolite Card
Formula: C6H13O7P (228.0399)
SMILES: C[C@@](O)(CCOP(O)(O)=O)CC(O)=O
Synonyms [en]
(R)-5-Phosphomevalonate; (R)-Mevalonic acid 5-phosphate; (R)-5-Phosphomevaloonic acid; mevalonate-P; 3R-methyl-3-hydroxypentanoic acid 5-phosphate; (R)-5-phosphomevalonic acid
Last reviewed on 2024-06-28.
Cite this Page
(R)-5-Phosphomevalonate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000000850). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Mevalonic acid-5P (CAS: 1189-94-2), also known as 5-phosphomevalonic acid, belongs to the class of organic compounds known as monoalkyl phosphates. These are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. Within humans, mevalonic acid-5P participates in many enzymatic reactions. In particular, mevalonic acid-5P can be biosynthesized from mevalonate; which is mediated by the enzyme mevalonate kinase. In addition, mevalonic acid-5P can be converted into mevalonic acid-5-pyrophosphate through its interaction with the enzyme phosphomevalonate kinase. In humans, mevalonic acid-5P is involved in the mevalonate pathway. Outside of the human body, mevalonic acid-5P has been detected, but not quantified in, several different foods, such as oriental wheat, devilfish, pepper (spice), redcurrants, and star fruits. This could make mevalonic acid-5P a potential biomarker for the consumption of these foods.
DBLinks
- CAS Registry Number: 73566-35-5
- PubChem CID: 439400
- ChEBI: 17436
- HMDB: HMDB0001343
- LipidMaps: LMFA01050415
- KEGG: C01107
- BioCyc:
- NCBI MeSH: phosphomevalonic acid
- Wikipedia:
Other DBLinks
- CAS Registry Number: 1189-94-2
- CAS Registry Number: 73566-35-5
- PubChem: 439400
- ChEBI: ChEBI:17436
- HMDB: HMDB0001343
- LipidMaps: LMFA01050415
- KEGG: C01107
- NCBI MeSH: phosphomevalonic acid
- RefMet: RM0153346
- Metlin: METLIN_3368
- Metlin: METLIN_74704
- Coconut NaturalProduct: CNP0359204.1
Class / Ontology
- WishartLab ClassyFire: [Phosphate esters] Phosphate esters
- RefMet: [Hydroxy FA] Hydroxy FA
- LipidMaps: [Hydroxy fatty acids [FA0105]] Hydroxy fatty acids [FA0105]
- ChEBI: [CHEBI:17436] (R)-5-phosphomevalonic acid
- Coconut NaturalProduct: [Hydroxy fatty acids] Hydroxy fatty acids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R02245 | 2.7.1.36 | ATP:(R)-mevalonate 5-phosphotransferase |
| KEGG:R03245 | 2.7.4.2 | ATP:(R)-5-phosphomevalonate phosphotransferase |
| KEGG:R10561 | 4.1.1.99 | ATP:phosphomevalonate carboxy-lyase (adding ATP; isopentenyl-phosphate-forming) |
| KEGG:R12894 | 4.2.1.182 | (R)-5-phosphomevalonate hydro-lyase |