Sialic acid metabolism

Li Y, Chen X. Sialic acid metabolism and sialyltransferases: natural functions and applications. Applied Microbiology and Biotechnology. 2012 Apr 13;94(4):887–905. doi: 10.1007/s00253-012-4040-1.; Wickramasinghe S, Medrano JF. Primer on genes encoding enzymes in sialic acid metabolism in mammals. Biochimie. 2011 Oct;93(10):1641–6. doi: 10.1016/j.biochi.2011.06.002. PMID: 21689720.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

N-Acetylneuraminate 9-phosphate

Formula: C11H20NO12P (389.0723090000001)

CAS ID: 37992-17-9

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.2.1.18 exo-alpha-sialidase acetylneuraminyl hydrolase
4.1.3.3 N-acetylneuraminate lyase aceneuramate pyruvate-lyase (N-acetyl-D-mannosamine-forming)


Proteins

Protein ID name full name