N-Acetylneuraminate 9-phosphate (BioCAD00000014582)

urine

Metabolite Card

Formula: C11H20NO12P (389.0723)
SMILES: [H][C@]1(OC(O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)COP(O)(O)=O

Synonyms [en]

N-Acetylneuraminate 9-phosphate; N-acetylneuraminic acid 9-phosphate; N-Acetyl- 9-(dihydrogen phosphate)-neuraminic acid; 5-dideoxy-9-phosphono-D-glycero-D-galacto-2-nonulosonic acid; 4-dihydroxyoxane-2-carboxylic acid; C06241

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

N-Acetylneuraminate 9-phosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000014582). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

N-Acetylneuraminic acid 9-phosphate is an intermediate in the synthesis of Acetylneuraminic acid, a process occurring in the cytosolic fraction by the human enzyme N-Acetylneuraminic acid 9-phosphate (Neu5Ac 9-P) synthase, that catalyzes the synthesis of N-Acetylneuraminic acid 9-phosphate, in a reaction by the mechanism of aldol condensation of phosphoenolpyruvate (PEP) with sugar substrates, ManNAc-6-P (N-acetylmannosamine 6-phosphate) or Man-6-P (mannose 6-phosphate). N-Acetylneuraminic acid 9-phosphate is converted to N-Acetylneuraminic acid by the enzyme N-acetylneuraminate-9-phosphate phosphatase. (PMID: 16503877, 6093772).

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 37992-17-9
  • PubChem: 440962
  • PubChem: 53477814
  • ChEBI: ChEBI:27438
  • HMDB: HMDB0004381
  • HMDB: HMDB0006268
  • HMDB: HMDB04381
  • HMDB: HMDB06268
  • KEGG: C06241
  • Metlin: METLIN_58238
  • Metlin: METLIN_58378
  • Coconut NaturalProduct: CNP0083564.1
  • Coconut NaturalProduct: CNP0083564.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01805 3.1.3.29 N-acetylneuraminate 9-phosphate phosphohydrolase
KEGG:R04435 2.5.1.56 phosphoenolpyruvate:N-acetyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming);
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-BTA-4085001 Sialic acid metabolism
Reactome:R-CFA-597592 Post-translational protein modification
Reactome:R-CFA-4085001 Sialic acid metabolism
Reactome:R-DRE-392499 Metabolism of proteins
Reactome:R-DRE-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-DME-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-GGA-597592 Post-translational protein modification
Reactome:R-GGA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-4085001 Sialic acid metabolism
Reactome:R-MMU-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-4085001 Sialic acid metabolism
Reactome:R-SSC-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-XTR-446203 Asparagine N-linked glycosylation
Reactome:R-BTA-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-CFA-446219 Synthesis of substrates in N-glycan biosythesis
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