Neurotransmitter release cycle

Edwards RH. The neurotransmitter cycle and quantal size. Neuron. 2007 Sep 20;55(6):835–58. doi: 10.1016/j.neuron.2007.09.001. PMID: 17880890.; Schoch S, Gundelfinger ED. Molecular organization of the presynaptic active zone. Cell Tissue Res. 2006 Nov;326(2):379–91. doi: 10.1007/s00441-006-0244-y. PMID: 16865347.; Becherer U, Rettig J. Vesicle pools, docking, priming, and release. Cell Tissue Res. 2006 Nov;326(2):393–407. doi: 10.1007/s00441-006-0243-z. PMID: 16819626.; Sudhof TC. The synaptic vesicle cycle. Annu Rev Neurosci. 2004;27():509–47. doi: 10.1146/annurev.neuro.26.041002.131412. PMID: 15217342.

Metabolites

3,4-Dihydroxymandelaldehyde

Formula: C8H8O4 (168.0422568)

CAS ID: 13023-73-9

Acetylcholine

Formula: C7H16NO2 (146.1180976)

CAS ID: 51-84-3

Ammonia

Formula: NH3 (17.0265478)

CAS ID: 7664-41-7

Choline

Formula: C5H14NO (104.10753340000001)

CAS ID: 62-49-7

Cl-

Formula: Cl (34.968853)

CAS ID: 16887-00-6

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Potassium cation

Formula: K (38.963708)

CAS ID: 24203-36-9

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

4-oxobutanoate

Formula: C4H5O3 (101.02386800000001)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.4.3.21 primary-amine oxidase primary-amine:oxygen oxidoreductase (deaminating)
1.4.3.4 monoamine oxidase amine:oxygen oxidoreductase (deaminating)
2.3.1.6 choline O-acetyltransferase acetyl-CoA:choline O-acetyltransferase


Proteins

Protein ID name full name