4-oxobutanoate (BioCAD00000466273)

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Metabolite Card

Formula: C4H5O3 (101.0239)
SMILES: [O-]C(=O)CCC=O

Synonyms [en]

succinate semialdehyde; succinyl semialdehyde; 4-Oxobutanoate; succ-S-ald; 4-oxobutyrate; Succinic semialdehyde monomer

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

4-oxobutanoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000466273). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

The conjugate base of 4-oxobutanoic acid; major species at pH 7.3." []

Entity Information

DBLinks

Other DBLinks
  • PubChem: 9543238
  • ChEBI: ChEBI:57706
  • KEGG: C00232
  • BioCyc: SUCC-S-ALD

Class / Ontology

Metabolic Network
ID EC Number Name
BioCyc:RXN-18258 1.14.13.239 GAMMA-BUTYROBETAINE + OXYGEN-MOLECULE + NADH-P-OR-NOP + PROTON --> SUCC-S-ALD + TRIMETHYLAMINE + NAD-P-OR-NOP + WATER
BioCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN 1.1.1.61 PROTON + NADH + SUCC-S-ALD --> NAD + 4-HYDROXY-BUTYRATE
BioCyc:SUCCSEMIALDDEHYDROG-RXN 1.2.1.79 SUCC-S-ALD + NADP + WATER --> SUC + NADPH + 2 PROTON
BioCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN 1.2.1.24 WATER + NAD + SUCC-S-ALD --> 2 PROTON + NADH + SUC
BioCyc:GABATRANSAM-RXN 2.6.1.19 2-KETOGLUTARATE + 4-AMINO-BUTYRATE<=>GLT + SUCC-S-ALD
Rhea:RHEA:10433 3.5.1.29 2-(acetamidomethylene)succinate + 2 H2O + H+ => succinate semialdehyde + acetate + NH4+ + CO2
Rhea:RHEA:10434 3.5.1.29 succinate semialdehyde + acetate + NH4+ + CO2 => 2-(acetamidomethylene)succinate + 2 H2O + H+
Rhea:RHEA:10435 3.5.1.29 2-(acetamidomethylene)succinate + 2 H2O + H+ <=> succinate semialdehyde + acetate + NH4+ + CO2
Rhea:RHEA:10525 4.1.1.71 2-oxoglutarate + H+ => succinate semialdehyde + CO2
Rhea:RHEA:10526 4.1.1.71 succinate semialdehyde + CO2 => 2-oxoglutarate + H+
Rhea:RHEA:10527 4.1.1.71 2-oxoglutarate + H+ <=> succinate semialdehyde + CO2
Rhea:RHEA:13214 1.2.1.16 succinate semialdehyde + NADP+ + H2O => succinate + NADPH + 2 H+
Rhea:RHEA:13215 1.2.1.16 succinate + NADPH + 2 H+ => succinate semialdehyde + NADP+ + H2O
Rhea:RHEA:13216 1.2.1.16 succinate semialdehyde + NADP+ + H2O <=> succinate + NADPH + 2 H+
Rhea:RHEA:13218 1.2.1.16 succinate semialdehyde + NAD+ + H2O => succinate + NADH + 2 H+
Rhea:RHEA:13219 1.2.1.16 succinate + NADH + 2 H+ => succinate semialdehyde + NAD+ + H2O
Rhea:RHEA:13220 1.2.1.16 succinate semialdehyde + NAD+ + H2O <=> succinate + NADH + 2 H+
Rhea:RHEA:23353 2.6.1.19 4-aminobutanoate + 2-oxoglutarate => succinate semialdehyde + L-glutamate
Rhea:RHEA:23354 2.6.1.19 succinate semialdehyde + L-glutamate => 4-aminobutanoate + 2-oxoglutarate
Rhea:RHEA:23355 2.6.1.19 4-aminobutanoate + 2-oxoglutarate <=> succinate semialdehyde + L-glutamate
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY-6535 4-aminobutyrate degradation
BioCyc:META_PWY-5677 succinate fermentation to butanoate
BioCyc:META_PWY-5499 vitamin B6 degradation
BioCyc:META_PWY-6993 nicotine degradation II (pyrrolidine pathway)
BioCyc:META_PWY-5022 4-aminobutanoate degradation V
BioCyc:META_PWY-6537 4-aminobutanoate degradation II
BioCyc:META_PWY-6535 4-aminobutanoate degradation I
BioCyc:META_PWY0-781 aspartate superpathway
BioCyc:ECO_PWY-6535 4-aminobutanoate degradation I
BioCyc:ECO_PWY-6537 4-aminobutanoate degradation II
BioCyc:YEAST_PWY-6536 4-aminobutyrate degradation
BioCyc:YEAST_GLUDEG-I-PWY-1 glutamate degradation to succinate
BioCyc:PLASMO_P105-PWY TCA cycle variation I
BioCyc:MTBH37RV_PWY-6537 4-aminobutanoate degradation II
BioCyc:MTBCDC1551_PWY-6535 4-aminobutanoate degradation I
BioCyc:ECOO157_PWY-6537 4-aminobutyrate degradation II
BioCyc:ECOL199310_4AMINOBUTMETAB-PWY superpathway of 4-aminobutyrate degradation
BioCyc:ANTHRA_PWY-6536 4-aminobutanoate degradation III
BioCyc:SCO_PWY-6537 4-aminobutanoate degradation II
BioCyc:FLY_4AMINOBUTMETAB-PWY superpathway of 4-aminobutanoate degradation
View All Pathways