Cell-cell junction organization

Rudini N, Dejana E. Adherens junctions. Curr Biol. 2008 Dec 09;18(23):R1080–2. doi: 10.1016/j.cub.2008.09.018. PMID: 19081036.; Ebnet K. Organization of multiprotein complexes at cell–cell junctions. Histochemistry and Cell Biology. 2008 Mar 26;130(1):1–20. doi: 10.1007/s00418-008-0418-7.; Hartsock A, Nelson WJ. Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2008 Mar;1778(3):660–9. doi: 10.1016/j.bbamem.2007.07.012.; Holthöfer B, Windoffer R, Troyanovsky S, Leube RE. Structure and function of desmosomes. Int Rev Cytol. 2007;264():65–163. doi: 10.1016/s0074-7696(07)64003-0. PMID: 17964922.; Furuse M, Tsukita S. Claudins in occluding junctions of humans and flies. Trends Cell Biol. 2006 Apr;16(4):181–8. doi: 10.1016/j.tcb.2006.02.006. PMID: 16537104.; Aijaz S, Balda MS, Matter K. Tight junctions: molecular architecture and function. Int Rev Cytol. 2006;248():261–98. doi: 10.1016/s0074-7696(06)48005-0. PMID: 16487793.; Schneeberger EE, Lynch RD. Structure, function, and regulation of cellular tight junctions. American Journal of Physiology-Lung Cellular and Molecular Physiology. 1992 Jun 01;262(6):L647–61. doi: 10.1152/ajplung.1992.262.6.l647.

Metabolites

beta-D-Glucose

Formula: C6H12O6 (180.0633852)

CAS ID: 492-61-5

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.-
1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase [histone H3]-N6,N6-dimethyl-L-lysine9,2-oxoglutarate:oxygen oxidoreductase
1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [histone H3]-N6,N6-dimethyl-L-lysine4:acceptor oxidoreductase (demethylating)
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase S-adenosyl-L-methionine:[histone H3]-L-lysine27 N6-methyltransferase
2.1.1.361 [histone H4]-lysine20 N-methyltransferase S-adenosyl-L-methionine:[histone H4]-L-lysine20 N6-methyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase
2.4.99.18 dolichyl-diphosphooligosaccharide-protein glycotransferase dolichyl-diphosphooligosaccharide:protein-L-asparagine N-beta-D-oligopolysaccharidotransferase
2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
3.2.1.106 mannosyl-oligosaccharide glucosidase Glc3Man9GlcNAc2-[protein] glucohydrolase (configuration-inverting)
3.2.1.207 mannosyl-oligosaccharide alpha-1,3-glucosidase Glc2Man9GlcNAc2-[protein] 3-alpha-glucohydrolase (configuration-inverting)
3.4.21.89 Signal peptidase I
3.5.1.98 histone deacetylase histone amidohydrolase
3.6.5.5 dynamin GTPase GTP phosphohydrolase (vesicle-releasing)


Proteins

Protein ID name full name